Click here to switch to the map view.

The map label for this gene is tpiA [H]

Identifier: 213691970

GI number: 213691970

Start: 1274780

End: 1275583

Strand: Direct

Name: tpiA [H]

Synonym: Blon_1088

Alternate gene names: 213691970

Gene position: 1274780-1275583 (Clockwise)

Preceding gene: 213691969

Following gene: 213691971

Centisome position: 45.0

GC content: 57.21

Gene sequence:

>804_bases
ATGGCGTCCAAACGCATTCCGTTGGTGGCCGGCAACTGGAAGATGAATTTCGACCATCTTGAAGCCACTTACTTCGTGCA
GAAGCTGGTATGGCTGTTGCGTGACGCTCACTTCGACTTCAAACGCTGCGAAGTCGCGCTTTTCCCCTCGTTCACGTCAT
TGCGCAGCGTACAGGTGCTGGTCGAAGCCGACAAGCTCCATGTCGCCTACGGCGCACAATCCGTTTCCGTGACCACCCAA
GGTGCCTTCACCGGCGATGTGTCCGCGGACATGATCGCCCATCTCGGCTGCTCATACGTCATCGTCGGCCACTCCGAACG
CCGCAAATACCATCCTGAAGATGACGCCAATATCGTCGATCAGGTACGTGCCGTGTTCGCCGCCGGCATGCAGCCGATTT
TGTGCGTCGGCGAAAGCTTCGAGGAACGACGTCAAGGCATTGAACTCGATTTCGCCGTGGGCCAGGTACGAGACGTCACC
CGCGATCTCAACGAAGAACAAGCCGCCGAACTCATCGTGGCCTACGAACCTGTCTGGGCCATTGGCACCGGCATGGTGGC
CACTCCGCAATCCGCCCAGGATGCCGCAAACGCCATCCGCAACGATTTGAAGACCACCTTTGGCACGAAGGTATCCGATA
GCGTACATATCCTGTACGGCGGATCGGTCACCTCGAAAAATGCGGCGGAACTCATTTCCCAGCCCGACGTTGACGGCTTC
CTGATCGGAGGGGCGGCCTTGGACGTTGAGGAACTCGCCAAAATCGCTCGATTGGCACTTAAATCCATGAAATCACGGAA
CTAA

Upstream 100 bases:

>100_bases
CCTCGAAGGCAAGGAGCTCCCTGGCCTGAAGGTGCTTGAGTAATCCATTTTCTAGCTCCCCTCCTTGAGGGGAGCTACGT
ATTTTCTAGAAGGGAAACAT

Downstream 100 bases:

>100_bases
TACCACGGTTTTCCCGTGTGTGCGCTATGCTGGTCAACAGTCCAATCAATCCGGAGGTACCCTGTGACCGCTCTTAAGAT
CACGCTGCAAGTCATCGTCG

Product: triosephosphate isomerase

Products: NA

Alternate protein names: TIM; Triose-phosphate isomerase [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MASKRIPLVAGNWKMNFDHLEATYFVQKLVWLLRDAHFDFKRCEVALFPSFTSLRSVQVLVEADKLHVAYGAQSVSVTTQ
GAFTGDVSADMIAHLGCSYVIVGHSERRKYHPEDDANIVDQVRAVFAAGMQPILCVGESFEERRQGIELDFAVGQVRDVT
RDLNEEQAAELIVAYEPVWAIGTGMVATPQSAQDAANAIRNDLKTTFGTKVSDSVHILYGGSVTSKNAAELISQPDVDGF
LIGGAALDVEELAKIARLALKSMKSRN

Sequences:

>Translated_267_residues
MASKRIPLVAGNWKMNFDHLEATYFVQKLVWLLRDAHFDFKRCEVALFPSFTSLRSVQVLVEADKLHVAYGAQSVSVTTQ
GAFTGDVSADMIAHLGCSYVIVGHSERRKYHPEDDANIVDQVRAVFAAGMQPILCVGESFEERRQGIELDFAVGQVRDVT
RDLNEEQAAELIVAYEPVWAIGTGMVATPQSAQDAANAIRNDLKTTFGTKVSDSVHILYGGSVTSKNAAELISQPDVDGF
LIGGAALDVEELAKIARLALKSMKSRN
>Mature_266_residues
ASKRIPLVAGNWKMNFDHLEATYFVQKLVWLLRDAHFDFKRCEVALFPSFTSLRSVQVLVEADKLHVAYGAQSVSVTTQG
AFTGDVSADMIAHLGCSYVIVGHSERRKYHPEDDANIVDQVRAVFAAGMQPILCVGESFEERRQGIELDFAVGQVRDVTR
DLNEEQAAELIVAYEPVWAIGTGMVATPQSAQDAANAIRNDLKTTFGTKVSDSVHILYGGSVTSKNAAELISQPDVDGFL
IGGAALDVEELAKIARLALKSMKSRN

Specific function: Plays an important role in several metabolic pathways. [C]

COG id: COG0149

COG function: function code G; Triosephosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the triosephosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4507645, Length=261, Percent_Identity=38.3141762452107, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI226529917, Length=250, Percent_Identity=38.4, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1790353, Length=255, Percent_Identity=39.2156862745098, Blast_Score=178, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17536593, Length=241, Percent_Identity=39.4190871369295, Blast_Score=160, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6320255, Length=246, Percent_Identity=40.2439024390244, Blast_Score=170, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28572008, Length=242, Percent_Identity=37.1900826446281, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI28572006, Length=242, Percent_Identity=37.1900826446281, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI28572004, Length=242, Percent_Identity=37.1900826446281, Blast_Score=156, Evalue=1e-38,

Paralogues:

None

Copy number: 1120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR022896
- InterPro:   IPR000652
- InterPro:   IPR020861 [H]

Pfam domain/function: PF00121 TIM [H]

EC number: =5.3.1.1 [H]

Molecular weight: Translated: 29189; Mature: 29058

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00171 TIM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKRIPLVAGNWKMNFDHLEATYFVQKLVWLLRDAHFDFKRCEVALFPSFTSLRSVQVL
CCCCCCCEEECCEEECHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCHHHHHHEEEE
VEADKLHVAYGAQSVSVTTQGAFTGDVSADMIAHLGCSYVIVGHSERRKYHPEDDANIVD
EEECEEEEEECCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHH
QVRAVFAAGMQPILCVGESFEERRQGIELDFAVGQVRDVTRDLNEEQAAELIVAYEPVWA
HHHHHHHCCCCCEEEECCCHHHHHCCCEEEEHHHHHHHHHHCCCHHHHHHEEEEECCHHH
IGTGMVATPQSAQDAANAIRNDLKTTFGTKVSDSVHILYGGSVTSKNAAELISQPDVDGF
HCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCEE
LIGGAALDVEELAKIARLALKSMKSRN
EECCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASKRIPLVAGNWKMNFDHLEATYFVQKLVWLLRDAHFDFKRCEVALFPSFTSLRSVQVL
CCCCCCEEECCEEECHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCHHHHHHEEEE
VEADKLHVAYGAQSVSVTTQGAFTGDVSADMIAHLGCSYVIVGHSERRKYHPEDDANIVD
EEECEEEEEECCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHH
QVRAVFAAGMQPILCVGESFEERRQGIELDFAVGQVRDVTRDLNEEQAAELIVAYEPVWA
HHHHHHHCCCCCEEEECCCHHHHHCCCEEEEHHHHHHHHHHCCCHHHHHHEEEEECCHHH
IGTGMVATPQSAQDAANAIRNDLKTTFGTKVSDSVHILYGGSVTSKNAAELISQPDVDGF
HCCCCEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCEE
LIGGAALDVEELAKIARLALKSMKSRN
EECCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA