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The map label for this gene is pcp [H]

Identifier: 213691950

GI number: 213691950

Start: 1249071

End: 1249718

Strand: Reverse

Name: pcp [H]

Synonym: Blon_1066

Alternate gene names: 213691950

Gene position: 1249718-1249071 (Counterclockwise)

Preceding gene: 213691951

Following gene: 213691946

Centisome position: 44.12

GC content: 59.41

Gene sequence:

>648_bases
ATGAGCAAGATTCTGGTGACCGGATTCGATCCGTTCGGCGGCGAGCCGGTTAACCCCGCATTCGAGGCAGTCAAGCTGTT
GCCGGATGAAATCGCCGGTGCGACAGTGGTGAAACTGGAGATTCCGACGGTGTTCACGCGCAGTGCGACCGTGGTTGAGG
AAGCCATGGTGCGCGAGCAGCCTGACTATGTGCTGTGCATTGGTCAGGCTGGTGGCCGGTCGGCTCTGACCGTGGAGAAA
GTGGCCATTAATTTGGCCGAGGCGCGTATTCCCGATAATGATGGCGAGCAGCCGTTCGATATGCCGCTACGGGAGGATGG
TGGCACCGCGTATTTCGCCACGTTGCCGGTCAAGGCCATGGTCAGGAACATCAATGACCACGGGATTCCCGCATTCATGT
CGTATACGGCAGGCACGTATGTGTGCAACAGCATCATGTATAACGTGTTGTATCTGATTGACCGCAAATTCCCCGGCGTC
AAGGGCGGTTTCATTCATGTGCCGTATGCGACCGCGCAGGGCGTGGGCAAGCCGAACGGCACGCCGACCATGGAGATCGC
GACCATGGCGCGCGGTATCGAAGCCGCCATCGAAGCCGCTGTGAGCACCGAAACCGACGCCACCGACATCCTGGGCGCAA
CCCACTGA

Upstream 100 bases:

>100_bases
CTGCATTGGTGATGATTGTGGTGCAGATCGTCTATATGCTGATCGCGCAATAACCTCGTTGTCCAGATACCACAACAATC
CGTGAAATAAGGAGCTAATG

Downstream 100 bases:

>100_bases
CATACAGACAGCGATGCCCCCACTGACAACTTCTGTCGGCGGGGGCATCGCTATGCGTTGAACGTTACAGTTCGCGCAGC
TGGGCGGCGATCTGGATGGA

Product: pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSKILVTGFDPFGGEPVNPAFEAVKLLPDEIAGATVVKLEIPTVFTRSATVVEEAMVREQPDYVLCIGQAGGRSALTVEK
VAINLAEARIPDNDGEQPFDMPLREDGGTAYFATLPVKAMVRNINDHGIPAFMSYTAGTYVCNSIMYNVLYLIDRKFPGV
KGGFIHVPYATAQGVGKPNGTPTMEIATMARGIEAAIEAAVSTETDATDILGATH

Sequences:

>Translated_215_residues
MSKILVTGFDPFGGEPVNPAFEAVKLLPDEIAGATVVKLEIPTVFTRSATVVEEAMVREQPDYVLCIGQAGGRSALTVEK
VAINLAEARIPDNDGEQPFDMPLREDGGTAYFATLPVKAMVRNINDHGIPAFMSYTAGTYVCNSIMYNVLYLIDRKFPGV
KGGFIHVPYATAQGVGKPNGTPTMEIATMARGIEAAIEAAVSTETDATDILGATH
>Mature_214_residues
SKILVTGFDPFGGEPVNPAFEAVKLLPDEIAGATVVKLEIPTVFTRSATVVEEAMVREQPDYVLCIGQAGGRSALTVEKV
AINLAEARIPDNDGEQPFDMPLREDGGTAYFATLPVKAMVRNINDHGIPAFMSYTAGTYVCNSIMYNVLYLIDRKFPGVK
GGFIHVPYATAQGVGKPNGTPTMEIATMARGIEAAIEAAVSTETDATDILGATH

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 22881; Mature: 22750

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01333 PYRASE_GLU ; PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKILVTGFDPFGGEPVNPAFEAVKLLPDEIAGATVVKLEIPTVFTRSATVVEEAMVREQ
CCCEEEECCCCCCCCCCCHHHHHHHHCHHHHCCEEEEEEECCEEECCHHHHHHHHHHHCC
PDYVLCIGQAGGRSALTVEKVAINLAEARIPDNDGEQPFDMPLREDGGTAYFATLPVKAM
CCEEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHH
VRNINDHGIPAFMSYTAGTYVCNSIMYNVLYLIDRKFPGVKGGFIHVPYATAQGVGKPNG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHCCCCCCCC
TPTMEIATMARGIEAAIEAAVSTETDATDILGATH
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
>Mature Secondary Structure 
SKILVTGFDPFGGEPVNPAFEAVKLLPDEIAGATVVKLEIPTVFTRSATVVEEAMVREQ
CCEEEECCCCCCCCCCCHHHHHHHHCHHHHCCEEEEEEECCEEECCHHHHHHHHHHHCC
PDYVLCIGQAGGRSALTVEKVAINLAEARIPDNDGEQPFDMPLREDGGTAYFATLPVKAM
CCEEEEEECCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHH
VRNINDHGIPAFMSYTAGTYVCNSIMYNVLYLIDRKFPGVKGGFIHVPYATAQGVGKPNG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCHHHCCCCCCCC
TPTMEIATMARGIEAAIEAAVSTETDATDILGATH
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]