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The map label for this gene is frr [H]

Identifier: 213691943

GI number: 213691943

Start: 1242510

End: 1243061

Strand: Direct

Name: frr [H]

Synonym: Blon_1059

Alternate gene names: 213691943

Gene position: 1242510-1243061 (Clockwise)

Preceding gene: 213691942

Following gene: 213691944

Centisome position: 43.86

GC content: 63.22

Gene sequence:

>552_bases
ATGTCCCTCATTGATCAGGCCAGGGAACAGATGGCCAAGACCGTGGAAAACACCAAGGAGAACTTCTCCGGCATCCGAAC
CGGCCGCGCCAACCCGGCCCTGCTCAACGGCATCACCGTGGACTACTACGGCGCCCCGACCCCGATCAAGGCCGTGGCCT
CCATCGGCGTGCCCGAGCCCCGCACCCTGTCCGTCACTCCGTTCGACGCCTCCCAGGCCGGCGCCGTCGAAAAGGCCCTG
CGCAATTCCGACCTCGGCGTCAGCCCGAACCGTGACGGCAACGTCATCCGTCTGACCATGCCGGAACTCACCGAGGAACG
CCGCAAGGAATACGTCAAGCTCGCCAAGGGCAAGGCCGAGGACGGCAAGGTGGCCGTGCGCAATATTCGCCGCAAGACCA
AGGAAGCCCTCGACAAGGCCGTCAAGGACGGCGAGATGGGCGAGGACGAAGGCGATCGTCTGCTGAAGGATCTCGACAAG
GTCACCAAGTCCGTCACCGATGAGATCGACGCCTTGCTGGAAAGCAAGCAGAAGGAGATCATGGAGGTCTGA

Upstream 100 bases:

>100_bases
TCCACCGCCGAATCGCGCGTGGCCGAATAGCATATGGACGTCCCGGATCGGGCGTTCGCTGACGAACAACATCGACAATC
ATCACATATAAGGAGTGAAC

Downstream 100 bases:

>100_bases
TTCGGACCTGGTACGGAGCATTATGGAACGCAACGAACAACTCCACGAGGAGGCCGAGGAGGCGCTCGACCAGATCAACA
AGAAGACCGGCCGCAACATG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSLIDQAREQMAKTVENTKENFSGIRTGRANPALLNGITVDYYGAPTPIKAVASIGVPEPRTLSVTPFDASQAGAVEKAL
RNSDLGVSPNRDGNVIRLTMPELTEERRKEYVKLAKGKAEDGKVAVRNIRRKTKEALDKAVKDGEMGEDEGDRLLKDLDK
VTKSVTDEIDALLESKQKEIMEV

Sequences:

>Translated_183_residues
MSLIDQAREQMAKTVENTKENFSGIRTGRANPALLNGITVDYYGAPTPIKAVASIGVPEPRTLSVTPFDASQAGAVEKAL
RNSDLGVSPNRDGNVIRLTMPELTEERRKEYVKLAKGKAEDGKVAVRNIRRKTKEALDKAVKDGEMGEDEGDRLLKDLDK
VTKSVTDEIDALLESKQKEIMEV
>Mature_182_residues
SLIDQAREQMAKTVENTKENFSGIRTGRANPALLNGITVDYYGAPTPIKAVASIGVPEPRTLSVTPFDASQAGAVEKALR
NSDLGVSPNRDGNVIRLTMPELTEERRKEYVKLAKGKAEDGKVAVRNIRRKTKEALDKAVKDGEMGEDEGDRLLKDLDKV
TKSVTDEIDALLESKQKEIMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=180, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786368, Length=173, Percent_Identity=46.8208092485549, Blast_Score=160, Evalue=3e-41,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20083; Mature: 19952

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIDQAREQMAKTVENTKENFSGIRTGRANPALLNGITVDYYGAPTPIKAVASIGVPEP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEECCCCCCHHHHHHHCCCCCC
RTLSVTPFDASQAGAVEKALRNSDLGVSPNRDGNVIRLTMPELTEERRKEYVKLAKGKAE
CEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCC
DGKVAVRNIRRKTKEALDKAVKDGEMGEDEGDRLLKDLDKVTKSVTDEIDALLESKQKEI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEV
HCC
>Mature Secondary Structure 
SLIDQAREQMAKTVENTKENFSGIRTGRANPALLNGITVDYYGAPTPIKAVASIGVPEP
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCEEEECCCCCCHHHHHHHCCCCCC
RTLSVTPFDASQAGAVEKALRNSDLGVSPNRDGNVIRLTMPELTEERRKEYVKLAKGKAE
CEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCC
DGKVAVRNIRRKTKEALDKAVKDGEMGEDEGDRLLKDLDKVTKSVTDEIDALLESKQKEI
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MEV
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA