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The map label for this gene is pyrH [H]

Identifier: 213691942

GI number: 213691942

Start: 1241699

End: 1242439

Strand: Direct

Name: pyrH [H]

Synonym: Blon_1058

Alternate gene names: 213691942

Gene position: 1241699-1242439 (Clockwise)

Preceding gene: 213691941

Following gene: 213691943

Centisome position: 43.83

GC content: 65.18

Gene sequence:

>741_bases
ATGACTGATAGCGACAAGCCGCGCAGGGTTCTGCTCAAACTGTCCGGTGAGGCGTTCGGTGGCGGTAAGGTCGGCATCGA
CACCCATGTGATCCGCCGCATCGCCGAGGAGATCGTCCCGGCCGTGCGGCAGGGCGTGCAGGTGGCCATCGTCGTCGGCG
GCGGTAACTTCTTCCGCGGCGCCGAACTCCAGCAGGCCGGCATCGACCGCTCCCGCGGCGATTACATGGGCATGCTCGGC
ACGGTGATGAACTGCCTCGCTCTGCAGGACTTCCTGGAGCAGGAGGGGCAGGCCACCCGCGTGCAGACCGCCATCACAAT
GGGACAGGTCGCCGAGCCGTATATTCCGCTCAAGGCCATCCGCCACCTCGAAAAGGGCCGTGTGGTGATCTTCGGCGCGG
GTGCCGGCATGCCGTATTTCTCCACCGATACGGTCTCCATCCAGCGCTCCCTCGAAATCCATTGCGACGAGGTGCTGATG
GGCAAGAACGGCGTCGACGGCGTCTACACCGCCGATCCGAACAAGGACGCGAACGCCAAGCGTTTCGAAACCCTGAGCTA
CAATCGCGCCCTCGTGGACAATCTGGCGGTCATGGACGCCTCGGCGTTGTCCATGGCCCGCGACAACAAGAAGCGCATCC
GCGTCTTCGGCCTCGAAGGGGCGGGCAACGTGACCCGCGCGCTGGTCGGGGACGAGATCGGCACGCTGGTCTCCACCGCC
GAATCGCGCGTGGCCGAATAG

Upstream 100 bases:

>100_bases
ATGGCGTGTTCCGAGGGTGTCGTTGCCCAAGGGTGTCGTTGTAAACCGATACGCTGGTCTACGGATAATTTCACATGTTC
GGTTCTGAGGAAGGCATGAT

Downstream 100 bases:

>100_bases
CATATGGACGTCCCGGATCGGGCGTTCGCTGACGAACAACATCGACAATCATCACATATAAGGAGTGAACATGTCCCTCA
TTGATCAGGCCAGGGAACAG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MTDSDKPRRVLLKLSGEAFGGGKVGIDTHVIRRIAEEIVPAVRQGVQVAIVVGGGNFFRGAELQQAGIDRSRGDYMGMLG
TVMNCLALQDFLEQEGQATRVQTAITMGQVAEPYIPLKAIRHLEKGRVVIFGAGAGMPYFSTDTVSIQRSLEIHCDEVLM
GKNGVDGVYTADPNKDANAKRFETLSYNRALVDNLAVMDASALSMARDNKKRIRVFGLEGAGNVTRALVGDEIGTLVSTA
ESRVAE

Sequences:

>Translated_246_residues
MTDSDKPRRVLLKLSGEAFGGGKVGIDTHVIRRIAEEIVPAVRQGVQVAIVVGGGNFFRGAELQQAGIDRSRGDYMGMLG
TVMNCLALQDFLEQEGQATRVQTAITMGQVAEPYIPLKAIRHLEKGRVVIFGAGAGMPYFSTDTVSIQRSLEIHCDEVLM
GKNGVDGVYTADPNKDANAKRFETLSYNRALVDNLAVMDASALSMARDNKKRIRVFGLEGAGNVTRALVGDEIGTLVSTA
ESRVAE
>Mature_245_residues
TDSDKPRRVLLKLSGEAFGGGKVGIDTHVIRRIAEEIVPAVRQGVQVAIVVGGGNFFRGAELQQAGIDRSRGDYMGMLGT
VMNCLALQDFLEQEGQATRVQTAITMGQVAEPYIPLKAIRHLEKGRVVIFGAGAGMPYFSTDTVSIQRSLEIHCDEVLMG
KNGVDGVYTADPNKDANAKRFETLSYNRALVDNLAVMDASALSMARDNKKRIRVFGLEGAGNVTRALVGDEIGTLVSTAE
SRVAE

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=241, Percent_Identity=45.643153526971, Blast_Score=201, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26473; Mature: 26342

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSDKPRRVLLKLSGEAFGGGKVGIDTHVIRRIAEEIVPAVRQGVQVAIVVGGGNFFRG
CCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
AELQQAGIDRSRGDYMGMLGTVMNCLALQDFLEQEGQATRVQTAITMGQVAEPYIPLKAI
CHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHH
RHLEKGRVVIFGAGAGMPYFSTDTVSIQRSLEIHCDEVLMGKNGVDGVYTADPNKDANAK
HHHCCCCEEEEECCCCCCCCCCCCEEEEEHEEEEEEEEEECCCCCCCEEECCCCCCCCCH
RFETLSYNRALVDNLAVMDASALSMARDNKKRIRVFGLEGAGNVTRALVGDEIGTLVSTA
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
ESRVAE
HHHCCC
>Mature Secondary Structure 
TDSDKPRRVLLKLSGEAFGGGKVGIDTHVIRRIAEEIVPAVRQGVQVAIVVGGGNFFRG
CCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCC
AELQQAGIDRSRGDYMGMLGTVMNCLALQDFLEQEGQATRVQTAITMGQVAEPYIPLKAI
CHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHH
RHLEKGRVVIFGAGAGMPYFSTDTVSIQRSLEIHCDEVLMGKNGVDGVYTADPNKDANAK
HHHCCCCEEEEECCCCCCCCCCCCEEEEEHEEEEEEEEEECCCCCCCEEECCCCCCCCCH
RFETLSYNRALVDNLAVMDASALSMARDNKKRIRVFGLEGAGNVTRALVGDEIGTLVSTA
HHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
ESRVAE
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA