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The map label for this gene is iscS [H]

Identifier: 213691805

GI number: 213691805

Start: 1077647

End: 1078894

Strand: Direct

Name: iscS [H]

Synonym: Blon_0913

Alternate gene names: 213691805

Gene position: 1077647-1078894 (Clockwise)

Preceding gene: 213691804

Following gene: 213691806

Centisome position: 38.04

GC content: 66.27

Gene sequence:

>1248_bases
ATGGCCGATACCCCCAACACGTCCAGCGAAGCCGGCGAACTGTACCTGGACGCCGCCGCCACCGAACCAGTGAGCCCGGC
AGTCATCGAGGCCATGACCCCGTTCCTGACTGAGGCCTACGCCAATCCGGCCAGTGTGCACCAGCCTGGCAAAACCGCGG
CCCGCGCGCTGGACGCGGCCCGCGCATCATTTGCCGCGGCATTGGGCGCCCGGCCGGATGACGTGATCTTCACCTCAGGC
GGCACCGAATCGGACAATCTGGCCATCAAAGGCATTGCCATGGCCCGCATGCGCAAGCTGGGCCTGCGGCCGGTCTACGG
ACTCGACGAAACCGATGGCAAACAGCTGGCAAGCAGCCGCCCGCGCATTATCATTTCCGCTATCGAGCACCCGGCCGTGG
CCCAATCGGCGGCATGGCTGCACGAATGGTTCGGTTTCGAAGTCGTGCGCATTCCCGTGGATGCGCAAGCACATCTCGAT
CTCGACGCACTTGAACGCGAGCTCGACGGCGAGGCCAGCGAACGTACCACGATGGTCTCCACCATACTTGCCAACAACGA
GGTCGGCACCGTGGAACCCGTGGAGGAACTGGTCCGCATCGCCCATGCGCACGGCGTGCCCATCCATGTGGACGCCGTAC
AGGCCGCCGGCCAGATTCCGATTCGTTTTCGTGACTGGGATGTGGACGCTCTGTCCGTATCCGGACACAAATTCGGCACG
CCCAAAGGTCTGGGCGCACTGCTGGTACGCGGCCGCACGCCCATCGAACCGGTGCTGTCCGGCGGCGGGCAGGAACGCGG
CCTGCGCTCCGGCACACAGAACGTGGCCGGTGCCGTGGCGCTCGCCATCGGACTCAATGAATCGAATGCGCGCATGCAGG
CGCAGTACCGTGAATTGGTCGCGTCCCGAGACATGCTCATCGATGCGGTTCGCCGGGTCGTGCCCCGCGCCGACCTGACC
GGCGACCCCGTGCGCCGTCTGCCCGGTCATGCCTCCTTCGTCTTTCCCGGCGTCACCGGCGAGGCGCTGCTCGTCGACCT
GGACGCGCGTGGCATCGCTGCCTCATCCGGCTCGGCCTGCGCCATCGGGCGCCACGAGATTCCTGCCACGTTGCTGGCGA
TGGGCCTCGAACCGTCCGTCGCCAAATCGGCATTGCGCATGACGTTCCGCAGGCCATTGGCCCGCGAGCAGATCGAACGG
GTCAGCCTGGCCCTCGAAGAGTCCTATGCCGGCCTGACCCGGCGTTGA

Upstream 100 bases:

>100_bases
GAGTGCCAGCCGTGGCCGCCACCGGCGTGGACGTGATCTCCGTGGGTGCGCTCACCCACTCCGTGCGTAGCATCGACCTC
GGATTGGATTGGAACTAGTC

Downstream 100 bases:

>100_bases
CCCGGCACCGTCGGGTCCGGCCCGGACAATCCGCGGGGGAGCGCTCGCCGTGTGGTCAAGCCGTGCAAGTATCATCGTGA
CGGTTTGTGTGCAGGTATAC

Product: aminotransferase, class V

Products: NA

Alternate protein names: NifS protein homolog [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MADTPNTSSEAGELYLDAAATEPVSPAVIEAMTPFLTEAYANPASVHQPGKTAARALDAARASFAAALGARPDDVIFTSG
GTESDNLAIKGIAMARMRKLGLRPVYGLDETDGKQLASSRPRIIISAIEHPAVAQSAAWLHEWFGFEVVRIPVDAQAHLD
LDALERELDGEASERTTMVSTILANNEVGTVEPVEELVRIAHAHGVPIHVDAVQAAGQIPIRFRDWDVDALSVSGHKFGT
PKGLGALLVRGRTPIEPVLSGGGQERGLRSGTQNVAGAVALAIGLNESNARMQAQYRELVASRDMLIDAVRRVVPRADLT
GDPVRRLPGHASFVFPGVTGEALLVDLDARGIAASSGSACAIGRHEIPATLLAMGLEPSVAKSALRMTFRRPLAREQIER
VSLALEESYAGLTRR

Sequences:

>Translated_415_residues
MADTPNTSSEAGELYLDAAATEPVSPAVIEAMTPFLTEAYANPASVHQPGKTAARALDAARASFAAALGARPDDVIFTSG
GTESDNLAIKGIAMARMRKLGLRPVYGLDETDGKQLASSRPRIIISAIEHPAVAQSAAWLHEWFGFEVVRIPVDAQAHLD
LDALERELDGEASERTTMVSTILANNEVGTVEPVEELVRIAHAHGVPIHVDAVQAAGQIPIRFRDWDVDALSVSGHKFGT
PKGLGALLVRGRTPIEPVLSGGGQERGLRSGTQNVAGAVALAIGLNESNARMQAQYRELVASRDMLIDAVRRVVPRADLT
GDPVRRLPGHASFVFPGVTGEALLVDLDARGIAASSGSACAIGRHEIPATLLAMGLEPSVAKSALRMTFRRPLAREQIER
VSLALEESYAGLTRR
>Mature_414_residues
ADTPNTSSEAGELYLDAAATEPVSPAVIEAMTPFLTEAYANPASVHQPGKTAARALDAARASFAAALGARPDDVIFTSGG
TESDNLAIKGIAMARMRKLGLRPVYGLDETDGKQLASSRPRIIISAIEHPAVAQSAAWLHEWFGFEVVRIPVDAQAHLDL
DALERELDGEASERTTMVSTILANNEVGTVEPVEELVRIAHAHGVPIHVDAVQAAGQIPIRFRDWDVDALSVSGHKFGTP
KGLGALLVRGRTPIEPVLSGGGQERGLRSGTQNVAGAVALAIGLNESNARMQAQYRELVASRDMLIDAVRRVVPRADLTG
DPVRRLPGHASFVFPGVTGEALLVDLDARGIAASSGSACAIGRHEIPATLLAMGLEPSVAKSALRMTFRRPLAREQIERV
SLALEESYAGLTRR

Specific function: Catalyzes the removal of elemental sulfur from cysteine to produce alanine [H]

COG id: COG1104

COG function: function code E; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=389, Percent_Identity=35.2185089974293, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI156713448, Length=426, Percent_Identity=33.0985915492958, Blast_Score=179, Evalue=4e-45,
Organism=Escherichia coli, GI48994898, Length=391, Percent_Identity=36.5728900255754, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787970, Length=437, Percent_Identity=26.0869565217391, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1789175, Length=380, Percent_Identity=28.1578947368421, Blast_Score=85, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI25143064, Length=403, Percent_Identity=36.7245657568238, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17533177, Length=341, Percent_Identity=30.4985337243402, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17543922, Length=231, Percent_Identity=26.4069264069264, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=409, Percent_Identity=36.1858190709046, Blast_Score=215, Evalue=1e-56,
Organism=Drosophila melanogaster, GI20129463, Length=400, Percent_Identity=36.25, Blast_Score=224, Evalue=9e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010240
- InterPro:   IPR017772
- InterPro:   IPR016454
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44007; Mature: 43876

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADTPNTSSEAGELYLDAAATEPVSPAVIEAMTPFLTEAYANPASVHQPGKTAARALDAA
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
RASFAAALGARPDDVIFTSGGTESDNLAIKGIAMARMRKLGLRPVYGLDETDGKQLASSR
HHHHHHHHCCCCCCEEEECCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHCCC
PRIIISAIEHPAVAQSAAWLHEWFGFEVVRIPVDAQAHLDLDALERELDGEASERTTMVS
CEEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHH
TILANNEVGTVEPVEELVRIAHAHGVPIHVDAVQAAGQIPIRFRDWDVDALSVSGHKFGT
HHHHCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCEEEECCCCEEEEECCCCCCC
PKGLGALLVRGRTPIEPVLSGGGQERGLRSGTQNVAGAVALAIGLNESNARMQAQYRELV
CCCCHHEEECCCCCHHHHHCCCCHHHHHHCCHHHHHCEEEEEEECCCCCHHHHHHHHHHH
ASRDMLIDAVRRVVPRADLTGDPVRRLPGHASFVFPGVTGEALLVDLDARGIAASSGSAC
HHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEECCCCCCEEEEEECCCCEECCCCCEE
AIGRHEIPATLLAMGLEPSVAKSALRMTFRRPLAREQIERVSLALEESYAGLTRR
ECCCCCCCHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ADTPNTSSEAGELYLDAAATEPVSPAVIEAMTPFLTEAYANPASVHQPGKTAARALDAA
CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
RASFAAALGARPDDVIFTSGGTESDNLAIKGIAMARMRKLGLRPVYGLDETDGKQLASSR
HHHHHHHHCCCCCCEEEECCCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCCCCHHHHCCC
PRIIISAIEHPAVAQSAAWLHEWFGFEVVRIPVDAQAHLDLDALERELDGEASERTTMVS
CEEEEEECCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHH
TILANNEVGTVEPVEELVRIAHAHGVPIHVDAVQAAGQIPIRFRDWDVDALSVSGHKFGT
HHHHCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCEEEECCCCEEEEECCCCCCC
PKGLGALLVRGRTPIEPVLSGGGQERGLRSGTQNVAGAVALAIGLNESNARMQAQYRELV
CCCCHHEEECCCCCHHHHHCCCCHHHHHHCCHHHHHCEEEEEEECCCCCHHHHHHHHHHH
ASRDMLIDAVRRVVPRADLTGDPVRRLPGHASFVFPGVTGEALLVDLDARGIAASSGSAC
HHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEEECCCCCCEEEEEECCCCEECCCCCEE
AIGRHEIPATLLAMGLEPSVAKSALRMTFRRPLAREQIERVSLALEESYAGLTRR
ECCCCCCCHHHHHHCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10930739 [H]