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The map label for this gene is nagB [H]

Identifier: 213691773

GI number: 213691773

Start: 1040906

End: 1041718

Strand: Direct

Name: nagB [H]

Synonym: Blon_0881

Alternate gene names: 213691773

Gene position: 1040906-1041718 (Clockwise)

Preceding gene: 213691771

Following gene: 213691774

Centisome position: 36.75

GC content: 63.96

Gene sequence:

>813_bases
ATGCCGGAAATCATCATTGTCAAGAACGAAGCCGAGGCCGGTGAGATCTACGGCCGTTGCGTGGCGGACCTGATCAAAGC
AAAGCCGGACGCCGTGCTGGGCCTGGCCACTGGTTCCAGCCCGCTGGCCGCCTATCAGGCGCTCGCCAAGATCGTCAAGG
ACGAGGCCATTGACGTTTCGGGCGTGCGTGGTTTCGCGCTTGACGAATACATCGGACTGCCGCTGACCCATCCTGAGTCC
TATCATGCGACCATCCATCGTACCGTGGTCGAACCGCTCGGCCTGGACCCAGCCAAGGTCCATGTGCCCGGCGACGTACT
CAACGGCACTCCGCTCGAAGACGGCGACAAAGTCGCGCTGGCCGGCCCGGCCTATGATCGTGCCATCGAAGCCGCTGGCG
GCATCGACGTGCAGATTCTCGGCATCGGCACCGACGGCCACGTCGGCTTCAACGAGCCCGGTTCCTCGCTGGCCTCCGGC
ACTCGTGTCAAGACCCTGGCCGAGCAGACCCGCGTCGACAACGCCCGCTTCTTCGACAACGACATCAACCAGGTGCCCAC
CCACTGCATCACGCAGGGTATTGGCACGATCATGAAGGCCCGTCACCTCGTGCTGCTGGCGTTCGGTGCCGGCAAGGCTG
AAGCCATCGAGGAGACGGTGGAAGGCGGCTTGTCCGCGTTCTGCCCGGCTTCCGCGCTGCAGATGCACCCGCACGCCACG
ATTATCGTGGATGAGGAGGCCGCCTCTCGTCTGCGCCACAAGGACTACTATCGCTACGCCTACACCCACAAGCCGGCCTG
GCAGGGCATCTGA

Upstream 100 bases:

>100_bases
CACATCACCCGGACGTGACAAGGATGTTGCCATTATCCGCAAGACGGGCGGCAGTACAGCGACTCGCATCGGGCGGGCCG
CACGGAACTGGAGGAAACCG

Downstream 100 bases:

>100_bases
TCCGATCCGTTCGCCCCATTGCTGAGCTTTCGAGCCTGCAAGCGGTCCATCGGGCCGCCTGCAGGCTCGTCTTGAGCGCA
AGACGAGCGGACGGGAAACC

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MPEIIIVKNEAEAGEIYGRCVADLIKAKPDAVLGLATGSSPLAAYQALAKIVKDEAIDVSGVRGFALDEYIGLPLTHPES
YHATIHRTVVEPLGLDPAKVHVPGDVLNGTPLEDGDKVALAGPAYDRAIEAAGGIDVQILGIGTDGHVGFNEPGSSLASG
TRVKTLAEQTRVDNARFFDNDINQVPTHCITQGIGTIMKARHLVLLAFGAGKAEAIEETVEGGLSAFCPASALQMHPHAT
IIVDEEAASRLRHKDYYRYAYTHKPAWQGI

Sequences:

>Translated_270_residues
MPEIIIVKNEAEAGEIYGRCVADLIKAKPDAVLGLATGSSPLAAYQALAKIVKDEAIDVSGVRGFALDEYIGLPLTHPES
YHATIHRTVVEPLGLDPAKVHVPGDVLNGTPLEDGDKVALAGPAYDRAIEAAGGIDVQILGIGTDGHVGFNEPGSSLASG
TRVKTLAEQTRVDNARFFDNDINQVPTHCITQGIGTIMKARHLVLLAFGAGKAEAIEETVEGGLSAFCPASALQMHPHAT
IIVDEEAASRLRHKDYYRYAYTHKPAWQGI
>Mature_269_residues
PEIIIVKNEAEAGEIYGRCVADLIKAKPDAVLGLATGSSPLAAYQALAKIVKDEAIDVSGVRGFALDEYIGLPLTHPESY
HATIHRTVVEPLGLDPAKVHVPGDVLNGTPLEDGDKVALAGPAYDRAIEAAGGIDVQILGIGTDGHVGFNEPGSSLASGT
RVKTLAEQTRVDNARFFDNDINQVPTHCITQGIGTIMKARHLVLLAFGAGKAEAIEETVEGGLSAFCPASALQMHPHATI
IVDEEAASRLRHKDYYRYAYTHKPAWQGI

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=259, Percent_Identity=38.996138996139, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI19923881, Length=259, Percent_Identity=38.996138996139, Blast_Score=186, Evalue=3e-47,
Organism=Escherichia coli, GI1786893, Length=257, Percent_Identity=37.7431906614786, Blast_Score=181, Evalue=4e-47,
Organism=Escherichia coli, GI1789530, Length=243, Percent_Identity=30.0411522633745, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI48994958, Length=243, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17554876, Length=267, Percent_Identity=40.4494382022472, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24581960, Length=256, Percent_Identity=39.453125, Blast_Score=175, Evalue=3e-44,
Organism=Drosophila melanogaster, GI19920764, Length=256, Percent_Identity=39.453125, Blast_Score=175, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 28678; Mature: 28547

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEIIIVKNEAEAGEIYGRCVADLIKAKPDAVLGLATGSSPLAAYQALAKIVKDEAIDVS
CCCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCC
GVRGFALDEYIGLPLTHPESYHATIHRTVVEPLGLDPAKVHVPGDVLNGTPLEDGDKVAL
CCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEE
AGPAYDRAIEAAGGIDVQILGIGTDGHVGFNEPGSSLASGTRVKTLAEQTRVDNARFFDN
ECCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCHHCCC
DINQVPTHCITQGIGTIMKARHLVLLAFGAGKAEAIEETVEGGLSAFCPASALQMHPHAT
CHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHCCHHHCCCHHHHEECCCEE
IIVDEEAASRLRHKDYYRYAYTHKPAWQGI
EEECHHHHHHHHHHHHHEEEEECCCCCCCC
>Mature Secondary Structure 
PEIIIVKNEAEAGEIYGRCVADLIKAKPDAVLGLATGSSPLAAYQALAKIVKDEAIDVS
CCEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCC
GVRGFALDEYIGLPLTHPESYHATIHRTVVEPLGLDPAKVHVPGDVLNGTPLEDGDKVAL
CCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEE
AGPAYDRAIEAAGGIDVQILGIGTDGHVGFNEPGSSLASGTRVKTLAEQTRVDNARFFDN
ECCHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHCCCHHHHHHHHHHCCCCHHCCC
DINQVPTHCITQGIGTIMKARHLVLLAFGAGKAEAIEETVEGGLSAFCPASALQMHPHAT
CHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHCCHHHCCCHHHHEECCCEE
IIVDEEAASRLRHKDYYRYAYTHKPAWQGI
EEECHHHHHHHHHHHHHEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA