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The map label for this gene is yqjI [H]

Identifier: 213691564

GI number: 213691564

Start: 768506

End: 770476

Strand: Reverse

Name: yqjI [H]

Synonym: Blon_0666

Alternate gene names: 213691564

Gene position: 770476-768506 (Counterclockwise)

Preceding gene: 213691565

Following gene: 213691563

Centisome position: 27.2

GC content: 58.4

Gene sequence:

>1971_bases
ATGGGTGTGACAGGCACCGGTAAAACGACCATGGCTCAGGAACTCGTAAACGAATTGGGATGGCCATATGCCGAAGCCGA
CGATTTCCATCCCCAAGCCAATATCGACAAAATGGCCTCTGGTCATCCACTGACCGATGAGGACCGTTGGCCCTGGCTTC
GCAGCCTACGCGATTGGATCACCGAGCAGGCAGGCAAGGGAGCCAACACCATCGTCACTTGTTCCGCGTTGAAACGCGCA
TATCGCGACATCCTACGAGAGGCGAACGCACAAGTCGTTTTCGTCGAGCTTGATCTCGATAAAACCGATATCGCCGAACG
TATGACGCAGCGTGAGCATTTCATGCCCGTCGAGCTTCTGCAATCGCAGATTGACACTTTGGAGCCTCTCGAGGCTGATG
AGCACGGCATACGGCTCATTTCCAACTTGCCTCCAGAGGTGCTATGCCACGAGGCATTGAGTCAATTGGGATTGGCTCTC
AGCAATATCATTCATTTGAACGAACGGCAACAGCAAGGGGATACAATCATGACAGCACAAGCTAACATCGGCGTTATCGG
TCTCGCTGCAATGGGCAGCAACCTGGCCCGCAATCTCGCCCACCACGGCAACACCGTGGCACTGTTCAATCGCCATTACT
CGCGTACTGAAAAGCTGCTGGCCGAGCACGGCACCGAAGGCAATTTCATTCCTGCTAAGACCATGGAGGAATTCGCCGCT
TCCCTGCAACGTCCTCGTACCGCCATCATCATGGTCAAGGCCGGAGCTCCGACCGATGCCGTGATCAAGCAGCTCGAAGA
GGCCTTCGAGCCTGGCGACATCATCGTCGACGGTGGAAACTCCTACTTCAAGGACACCATCAAGCGTGAGAAGGAAGTGC
GCGCCGCTGGATTCCACTTCGTCGGTTGCGGCGTGTCCGGTGGCGAGGAAGGCGCTCTGAACGGTCCTTCCCTTATGCCG
GGAGGCACCGCCGAATCGTGGAAGACCCTTGGTCCGATTCTTGAATCCATCGCTGCCAAGGTCGACGGTGAGCCTTGCGT
CACGCATATCGGCACCGATGGCGCCGGACATTTCGTCAAGATGGTGCACAACGGCATCGAATACGCCGACATGCAGGTCA
TCGGCGAAGCCTACGACATTCTGCGTCGCGGTCTGGGACTTTCCCCCGAGGCGATTGGCGATGTGTTCGCCGATTGGAAC
AAGGGCGATCTTGATTCCTATCTGATTGAGATCACCGCCGATATCCTTCATGAGAAGGACGAGCGTACCGGCAAGCCGTT
CGTCGATGTCGTCGTCGATCGCGCAGGTATGAAGGGCACTGGTACGTGGACGGTGCAGACCGCACTGGAGTTCGGTTCCC
CTGTCACCGGCATCGGAGAGGCTGTGTTCGCGCGTGCGCTGTCGAGCCATCCTGAGCTGAGGCAAGCCGCGCAGGACAGC
GCGCCTGCAGGCCCCAACAATGCCATCACCGTGGGGGACCAGGCGACCTTCATCGAAGACGTGCGTCGCGCATTGCTCGC
TTCCAAGATCATCGCCTATTCTCAGGGACTCAACGAGATCGAGGATGGCGCCAAGCAGTATGGCTGGAACATCGACCTGG
GAGCCGTCGCCAAGATCTGGCGTGGAGGCTGCATCATTCGTGCGAAGTTCCTCAACCGCATTACCGACGCCTACACCAAC
GGCCATCCTGCGGCACTGGCGCTCGATCCGTACTTCGCCAAGTTCCTTGCCGACGCGCAGGAGTCTTGGCGTCGAGTCAT
CAAGGCGGCCATCGACGCAGGCATTCCGACGCCTGTCTTCTCCAGCTCCTTGGCGTACTACGACGGACTGCGTTCGAAGC
GTCTGCCTACTGCACTGACCCAGGCACAGCGTGACTTCTTCGGAGCTCACACCTATGGTCGCGTGGATACGCCCGGCGTC
TTCCACAAGCTGTGGGCTGAGCAGAACCGCCCGGAAGAGCAGCAGGCCTGA

Upstream 100 bases:

>100_bases
TCATTATCGGGCGATTGGAACGTATTCGGGTCTGATCGCCCTTTCCATTCAAGGAGAATCCATGCTTGATTCCAATGCCG
AACCCGTCAGTCTGATCGTC

Downstream 100 bases:

>100_bases
TGTAAAAGGGAAATAAAAAGCTGACGCTTTTAACCGTACCCCGATTATCGGACTGAAGAAATTCGGATGATAATCGAGAT
GCGGTTTTCTTTTATGGATA

Product: 6-phosphogluconate dehydrogenase, decarboxylating

Products: NA

Alternate protein names: GNTZII [H]

Number of amino acids: Translated: 656; Mature: 655

Protein sequence:

>656_residues
MGVTGTGKTTMAQELVNELGWPYAEADDFHPQANIDKMASGHPLTDEDRWPWLRSLRDWITEQAGKGANTIVTCSALKRA
YRDILREANAQVVFVELDLDKTDIAERMTQREHFMPVELLQSQIDTLEPLEADEHGIRLISNLPPEVLCHEALSQLGLAL
SNIIHLNERQQQGDTIMTAQANIGVIGLAAMGSNLARNLAHHGNTVALFNRHYSRTEKLLAEHGTEGNFIPAKTMEEFAA
SLQRPRTAIIMVKAGAPTDAVIKQLEEAFEPGDIIVDGGNSYFKDTIKREKEVRAAGFHFVGCGVSGGEEGALNGPSLMP
GGTAESWKTLGPILESIAAKVDGEPCVTHIGTDGAGHFVKMVHNGIEYADMQVIGEAYDILRRGLGLSPEAIGDVFADWN
KGDLDSYLIEITADILHEKDERTGKPFVDVVVDRAGMKGTGTWTVQTALEFGSPVTGIGEAVFARALSSHPELRQAAQDS
APAGPNNAITVGDQATFIEDVRRALLASKIIAYSQGLNEIEDGAKQYGWNIDLGAVAKIWRGGCIIRAKFLNRITDAYTN
GHPAALALDPYFAKFLADAQESWRRVIKAAIDAGIPTPVFSSSLAYYDGLRSKRLPTALTQAQRDFFGAHTYGRVDTPGV
FHKLWAEQNRPEEQQA

Sequences:

>Translated_656_residues
MGVTGTGKTTMAQELVNELGWPYAEADDFHPQANIDKMASGHPLTDEDRWPWLRSLRDWITEQAGKGANTIVTCSALKRA
YRDILREANAQVVFVELDLDKTDIAERMTQREHFMPVELLQSQIDTLEPLEADEHGIRLISNLPPEVLCHEALSQLGLAL
SNIIHLNERQQQGDTIMTAQANIGVIGLAAMGSNLARNLAHHGNTVALFNRHYSRTEKLLAEHGTEGNFIPAKTMEEFAA
SLQRPRTAIIMVKAGAPTDAVIKQLEEAFEPGDIIVDGGNSYFKDTIKREKEVRAAGFHFVGCGVSGGEEGALNGPSLMP
GGTAESWKTLGPILESIAAKVDGEPCVTHIGTDGAGHFVKMVHNGIEYADMQVIGEAYDILRRGLGLSPEAIGDVFADWN
KGDLDSYLIEITADILHEKDERTGKPFVDVVVDRAGMKGTGTWTVQTALEFGSPVTGIGEAVFARALSSHPELRQAAQDS
APAGPNNAITVGDQATFIEDVRRALLASKIIAYSQGLNEIEDGAKQYGWNIDLGAVAKIWRGGCIIRAKFLNRITDAYTN
GHPAALALDPYFAKFLADAQESWRRVIKAAIDAGIPTPVFSSSLAYYDGLRSKRLPTALTQAQRDFFGAHTYGRVDTPGV
FHKLWAEQNRPEEQQA
>Mature_655_residues
GVTGTGKTTMAQELVNELGWPYAEADDFHPQANIDKMASGHPLTDEDRWPWLRSLRDWITEQAGKGANTIVTCSALKRAY
RDILREANAQVVFVELDLDKTDIAERMTQREHFMPVELLQSQIDTLEPLEADEHGIRLISNLPPEVLCHEALSQLGLALS
NIIHLNERQQQGDTIMTAQANIGVIGLAAMGSNLARNLAHHGNTVALFNRHYSRTEKLLAEHGTEGNFIPAKTMEEFAAS
LQRPRTAIIMVKAGAPTDAVIKQLEEAFEPGDIIVDGGNSYFKDTIKREKEVRAAGFHFVGCGVSGGEEGALNGPSLMPG
GTAESWKTLGPILESIAAKVDGEPCVTHIGTDGAGHFVKMVHNGIEYADMQVIGEAYDILRRGLGLSPEAIGDVFADWNK
GDLDSYLIEITADILHEKDERTGKPFVDVVVDRAGMKGTGTWTVQTALEFGSPVTGIGEAVFARALSSHPELRQAAQDSA
PAGPNNAITVGDQATFIEDVRRALLASKIIAYSQGLNEIEDGAKQYGWNIDLGAVAKIWRGGCIIRAKFLNRITDAYTNG
HPAALALDPYFAKFLADAQESWRRVIKAAIDAGIPTPVFSSSLAYYDGLRSKRLPTALTQAQRDFFGAHTYGRVDTPGVF
HKLWAEQNRPEEQQA

Specific function: Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH [H]

COG id: COG0362

COG function: function code G; 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=470, Percent_Identity=48.936170212766, Blast_Score=437, Evalue=1e-122,
Organism=Homo sapiens, GI299758445, Length=158, Percent_Identity=42.4050632911392, Blast_Score=128, Evalue=2e-29,
Organism=Escherichia coli, GI1788341, Length=469, Percent_Identity=52.4520255863539, Blast_Score=503, Evalue=1e-143,
Organism=Escherichia coli, GI1790719, Length=138, Percent_Identity=46.3768115942029, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI87082265, Length=141, Percent_Identity=39.7163120567376, Blast_Score=115, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17542558, Length=472, Percent_Identity=49.364406779661, Blast_Score=464, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI25146487, Length=143, Percent_Identity=40.5594405594406, Blast_Score=111, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321695, Length=457, Percent_Identity=50.7658643326039, Blast_Score=454, Evalue=1e-128,
Organism=Saccharomyces cerevisiae, GI6321977, Length=456, Percent_Identity=51.7543859649123, Blast_Score=439, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6320454, Length=137, Percent_Identity=39.4160583941606, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24639279, Length=469, Percent_Identity=47.1215351812367, Blast_Score=415, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR006114
- InterPro:   IPR006113
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR012284
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: =1.1.1.44 [H]

Molecular weight: Translated: 71499; Mature: 71368

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVTGTGKTTMAQELVNELGWPYAEADDFHPQANIDKMASGHPLTDEDRWPWLRSLRDWI
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHH
TEQAGKGANTIVTCSALKRAYRDILREANAQVVFVELDLDKTDIAERMTQREHFMPVELL
HHHCCCCCCCEEEHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHH
QSQIDTLEPLEADEHGIRLISNLPPEVLCHEALSQLGLALSNIIHLNERQQQGDTIMTAQ
HHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEE
ANIGVIGLAAMGSNLARNLAHHGNTVALFNRHYSRTEKLLAEHGTEGNFIPAKTMEEFAA
CCCCEEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
SLQRPRTAIIMVKAGAPTDAVIKQLEEAFEPGDIIVDGGNSYFKDTIKREKEVRAAGFHF
HHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCEEE
VGCGVSGGEEGALNGPSLMPGGTAESWKTLGPILESIAAKVDGEPCVTHIGTDGAGHFVK
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
MVHNGIEYADMQVIGEAYDILRRGLGLSPEAIGDVFADWNKGDLDSYLIEITADILHEKD
HHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCH
ERTGKPFVDVVVDRAGMKGTGTWTVQTALEFGSPVTGIGEAVFARALSSHPELRQAAQDS
HCCCCCHHHHHHHCCCCCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHCC
APAGPNNAITVGDQATFIEDVRRALLASKIIAYSQGLNEIEDGAKQYGWNIDLGAVAKIW
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHH
RGGCIIRAKFLNRITDAYTNGHPAALALDPYFAKFLADAQESWRRVIKAAIDAGIPTPVF
CCCCEEHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SSSLAYYDGLRSKRLPTALTQAQRDFFGAHTYGRVDTPGVFHKLWAEQNRPEEQQA
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure 
GVTGTGKTTMAQELVNELGWPYAEADDFHPQANIDKMASGHPLTDEDRWPWLRSLRDWI
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHH
TEQAGKGANTIVTCSALKRAYRDILREANAQVVFVELDLDKTDIAERMTQREHFMPVELL
HHHCCCCCCCEEEHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHCCCCHHHH
QSQIDTLEPLEADEHGIRLISNLPPEVLCHEALSQLGLALSNIIHLNERQQQGDTIMTAQ
HHHHHHCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEEE
ANIGVIGLAAMGSNLARNLAHHGNTVALFNRHYSRTEKLLAEHGTEGNFIPAKTMEEFAA
CCCCEEEHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
SLQRPRTAIIMVKAGAPTDAVIKQLEEAFEPGDIIVDGGNSYFKDTIKREKEVRAAGFHF
HHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHCCEEE
VGCGVSGGEEGALNGPSLMPGGTAESWKTLGPILESIAAKVDGEPCVTHIGTDGAGHFVK
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHH
MVHNGIEYADMQVIGEAYDILRRGLGLSPEAIGDVFADWNKGDLDSYLIEITADILHEKD
HHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCH
ERTGKPFVDVVVDRAGMKGTGTWTVQTALEFGSPVTGIGEAVFARALSSHPELRQAAQDS
HCCCCCHHHHHHHCCCCCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHCC
APAGPNNAITVGDQATFIEDVRRALLASKIIAYSQGLNEIEDGAKQYGWNIDLGAVAKIW
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHH
RGGCIIRAKFLNRITDAYTNGHPAALALDPYFAKFLADAQESWRRVIKAAIDAGIPTPVF
CCCCEEHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
SSSLAYYDGLRSKRLPTALTQAQRDFFGAHTYGRVDTPGVFHKLWAEQNRPEEQQA
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10568751; 9298659 [H]