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The map label for this gene is xseA [H]

Identifier: 213691511

GI number: 213691511

Start: 692462

End: 693820

Strand: Reverse

Name: xseA [H]

Synonym: Blon_0611

Alternate gene names: 213691511

Gene position: 693820-692462 (Counterclockwise)

Preceding gene: 213691523

Following gene: 213691510

Centisome position: 24.49

GC content: 60.85

Gene sequence:

>1359_bases
ATGGGCTACCCATCTACCGGCCGTCCACCGACCGCCGCTTCACTGGCCTCGGCTGGCTTTGAGCCGGGTCAAGGCACTTT
CGCGCCTGATCAGGGCACCATCAATCTGCCGAATGAGCCTCGCCCTATCGATCAGCTGCCTGCACGCGCCGCTGAAACCA
GCGCGCAAAATCCGTGGCCGGTAAGTGTGCTGAGCCAGAAGTTCTACGGTGCCGTGGAACGATGGCCGTCCGCGTGGGTC
ACCGGCCAGATCACGCAGATCAATACCCGTCGCGCCGGCTCGGCCTACATCACGCTGCGCGACGACTTCGAGGATATCGC
CATGGAAGTCAATGGCTTCGGCAGGTTCGCGGCCGCGGCCAGCCAGTTCGTTCAGGGCGACCGCGTGGTGATTCATGGCA
AACCGAACCTGTGGATGAAGCGCACTTCGCTGTCGTTGCGCGGGGACACGATTCTCAAGGTCGGAGCCGGTGGCAGCCTC
AAGGCCATGATCGACGAATTGCGCAAGCAGCTTAAGGGCGAGGGCCTGTTCGATGCCGATCACAAACTGCCTCTCCCGGA
GTTTCCGAAGACTATTGGCCTGATTTGCGCACCTCAGGCACGTGCGGAAGGCGATGTGATCACCAATGTGAACCTTCGTT
GGCCTTCCGTAACCTTCAAGGTGGTCCATGTGCATGTTCAGGGCGAGCAATGCCCGGCCGAAGTGGTTCAGGCCATTGCA
CAACTCGATGCCGACCCGAGCGTGGATGTGATCATCGTGGCCCGTGGCGGCGGCTCGTTTGAGGATCTCATCGGTTTCTC
GGATGAGCGTGTGGTTCGTGCGGCGTATGCCTGCACCACACCATTAATCTCCTCCATCGGGCATGAGGATGACTGGACGT
TGCTGGATCTGGTCGCCGATCTTAGAGCCTCCACCCCCACCGATGCGGCCAAGCGCGTGGTACCGGATGTGCGTGAGCAG
TCGCAGCTCATCGAAGGTGCCATCGACCGTATGCGACTGCGGGTCCGTTCGCGCGTGGAGAACGAGATTCGACTTATCGA
GGGATATGCGAACCGGCCAAGCCTGACCCAACCGCATACCATGCTCGAACCGCATCAGCGGCTAATCGACGATTCCCTGC
AGCGGCTTGACATCGGCCTGCGACGCATCGTGGACGATGCCCAGCTCACCGTCGAGCGAGCTCACGCCTCACTGACCGCA
CTCAGCCCGCAATCCACATTGAACCGAGGCTATGCGGTGGTGCAGTCCTCCGATGGCCACGTACTAGACGATGCTTCGCA
GGTAAGCCCTGGGGATGACATCACCGTCACCTTGAAGAAGGGTGTCATTACCGCAACCACCACATCCGCAACCGCGTGA

Upstream 100 bases:

>100_bases
TCGTACGGTTCTCGCATTCATCATCACACCGTTTTCAGGCGACGGTAAATATTTACCGTCATCAACCAACGCACTTATAG
TGGAGTGCATGACTACTGCA

Downstream 100 bases:

>100_bases
CACTCCATACGCAGCCACGCATATATACCATATATATATAAGGAGAACATCATGACCGAAAACGCCGCATCCACCGACAA
GAACAACCCCGCCTCGTCCC

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MGYPSTGRPPTAASLASAGFEPGQGTFAPDQGTINLPNEPRPIDQLPARAAETSAQNPWPVSVLSQKFYGAVERWPSAWV
TGQITQINTRRAGSAYITLRDDFEDIAMEVNGFGRFAAAASQFVQGDRVVIHGKPNLWMKRTSLSLRGDTILKVGAGGSL
KAMIDELRKQLKGEGLFDADHKLPLPEFPKTIGLICAPQARAEGDVITNVNLRWPSVTFKVVHVHVQGEQCPAEVVQAIA
QLDADPSVDVIIVARGGGSFEDLIGFSDERVVRAAYACTTPLISSIGHEDDWTLLDLVADLRASTPTDAAKRVVPDVREQ
SQLIEGAIDRMRLRVRSRVENEIRLIEGYANRPSLTQPHTMLEPHQRLIDDSLQRLDIGLRRIVDDAQLTVERAHASLTA
LSPQSTLNRGYAVVQSSDGHVLDDASQVSPGDDITVTLKKGVITATTTSATA

Sequences:

>Translated_452_residues
MGYPSTGRPPTAASLASAGFEPGQGTFAPDQGTINLPNEPRPIDQLPARAAETSAQNPWPVSVLSQKFYGAVERWPSAWV
TGQITQINTRRAGSAYITLRDDFEDIAMEVNGFGRFAAAASQFVQGDRVVIHGKPNLWMKRTSLSLRGDTILKVGAGGSL
KAMIDELRKQLKGEGLFDADHKLPLPEFPKTIGLICAPQARAEGDVITNVNLRWPSVTFKVVHVHVQGEQCPAEVVQAIA
QLDADPSVDVIIVARGGGSFEDLIGFSDERVVRAAYACTTPLISSIGHEDDWTLLDLVADLRASTPTDAAKRVVPDVREQ
SQLIEGAIDRMRLRVRSRVENEIRLIEGYANRPSLTQPHTMLEPHQRLIDDSLQRLDIGLRRIVDDAQLTVERAHASLTA
LSPQSTLNRGYAVVQSSDGHVLDDASQVSPGDDITVTLKKGVITATTTSATA
>Mature_451_residues
GYPSTGRPPTAASLASAGFEPGQGTFAPDQGTINLPNEPRPIDQLPARAAETSAQNPWPVSVLSQKFYGAVERWPSAWVT
GQITQINTRRAGSAYITLRDDFEDIAMEVNGFGRFAAAASQFVQGDRVVIHGKPNLWMKRTSLSLRGDTILKVGAGGSLK
AMIDELRKQLKGEGLFDADHKLPLPEFPKTIGLICAPQARAEGDVITNVNLRWPSVTFKVVHVHVQGEQCPAEVVQAIAQ
LDADPSVDVIIVARGGGSFEDLIGFSDERVVRAAYACTTPLISSIGHEDDWTLLDLVADLRASTPTDAAKRVVPDVREQS
QLIEGAIDRMRLRVRSRVENEIRLIEGYANRPSLTQPHTMLEPHQRLIDDSLQRLDIGLRRIVDDAQLTVERAHASLTAL
SPQSTLNRGYAVVQSSDGHVLDDASQVSPGDDITVTLKKGVITATTTSATA

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=414, Percent_Identity=29.2270531400966, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 48971; Mature: 48840

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYPSTGRPPTAASLASAGFEPGQGTFAPDQGTINLPNEPRPIDQLPARAAETSAQNPWP
CCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCHHHHCCCCCCCC
VSVLSQKFYGAVERWPSAWVTGQITQINTRRAGSAYITLRDDFEDIAMEVNGFGRFAAAA
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEECCCHHHHHHHHCCCHHHHHHH
SQFVQGDRVVIHGKPNLWMKRTSLSLRGDTILKVGAGGSLKAMIDELRKQLKGEGLFDAD
HHHHCCCEEEEECCCCCEEEECEEEECCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
HKLPLPEFPKTIGLICAPQARAEGDVITNVNLRWPSVTFKVVHVHVQGEQCPAEVVQAIA
CCCCCCCCCHHHCEEECCCCCCCCCEEEEEEEECCCEEEEEEEEEECCCCCHHHHHHHHH
QLDADPSVDVIIVARGGGSFEDLIGFSDERVVRAAYACTTPLISSIGHEDDWTLLDLVAD
HCCCCCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LRASTPTDAAKRVVPDVREQSQLIEGAIDRMRLRVRSRVENEIRLIEGYANRPSLTQPHT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCH
MLEPHQRLIDDSLQRLDIGLRRIVDDAQLTVERAHASLTALSPQSTLNRGYAVVQSSDGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCCEEEEECCCCC
VLDDASQVSPGDDITVTLKKGVITATTTSATA
EECCCCCCCCCCCEEEEEECCEEEEECCCCCC
>Mature Secondary Structure 
GYPSTGRPPTAASLASAGFEPGQGTFAPDQGTINLPNEPRPIDQLPARAAETSAQNPWP
CCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHCCHHHHCCCCCCCC
VSVLSQKFYGAVERWPSAWVTGQITQINTRRAGSAYITLRDDFEDIAMEVNGFGRFAAAA
HHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEECCCHHHHHHHHCCCHHHHHHH
SQFVQGDRVVIHGKPNLWMKRTSLSLRGDTILKVGAGGSLKAMIDELRKQLKGEGLFDAD
HHHHCCCEEEEECCCCCEEEECEEEECCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCC
HKLPLPEFPKTIGLICAPQARAEGDVITNVNLRWPSVTFKVVHVHVQGEQCPAEVVQAIA
CCCCCCCCCHHHCEEECCCCCCCCCEEEEEEEECCCEEEEEEEEEECCCCCHHHHHHHHH
QLDADPSVDVIIVARGGGSFEDLIGFSDERVVRAAYACTTPLISSIGHEDDWTLLDLVAD
HCCCCCCCCEEEEECCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LRASTPTDAAKRVVPDVREQSQLIEGAIDRMRLRVRSRVENEIRLIEGYANRPSLTQPHT
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCH
MLEPHQRLIDDSLQRLDIGLRRIVDDAQLTVERAHASLTALSPQSTLNRGYAVVQSSDGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHCCCEEEEECCCCC
VLDDASQVSPGDDITVTLKKGVITATTTSATA
EECCCCCCCCCCCEEEEEECCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]