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The map label for this gene is gltA2 [H]

Identifier: 213691496

GI number: 213691496

Start: 672661

End: 673953

Strand: Direct

Name: gltA2 [H]

Synonym: Blon_0594

Alternate gene names: 213691496

Gene position: 672661-673953 (Clockwise)

Preceding gene: 213691495

Following gene: 213691499

Centisome position: 23.75

GC content: 58.78

Gene sequence:

>1293_bases
ATGGCAACGGCACAACTTGATGTCGATTCGAACAAGTTCAACCTGCCCGTGGTGAAGGCTAGTGCAGGGCCGGATGGCAT
CGTCGTTTCCAAGCTGCGCAATGACGGCTGGGTAACGCTCGACCCCGGATTCCTCACCACCGCACAGTGCGAATCGAAAA
TCACCTACATCGACGGCAAGCATTCGATCCTGCGCTACCGTGGCTACCCCATCGAGCAGTTGTGCGAGAACTCCGATTTT
CTGGAAGTGGCGTGGCTGCTGCGCCACGGCGAGCTGCCGAGCAGGGCTGAGTATGAGCAGTTCTGCGCGGACATCAACCA
CAAGACGATGGTTGGCGAAGACTTCCGTACCTTCATGGGTTCGTTCCCGCGCTCCGCTCATCCGATGAGCGTGCTTGCCT
CCGCCATCAATGCGCTGGCCACGTTCTATCCGGACACCACCGATATCTCCGACACCGACCAGCTCGATGAGGCCGCCAAG
ATCATCATGGCCAAGGCCCGCACGATTGTGTCGTACATCTTCCGCCGTCGTCGCGATGAGCCGATGCTGTACCCCGATTA
CGCGCGTGGCTATGTGGACGACTTCCTGCGCATGTGCTTCGCTGTGCCGTACGAGCCGTTCGAATCTGACCCGTTGTATG
TGCATGCTTTGGGTCGTTTGTTGATTATTCATGCCGATCATGAGCAGAACTGCTCGACCTCGGTGGTGCGTATCGCCGGT
TCCGCCCACGCTAACCTGTATTCGGCGGTGGCCGCTGGTGTCAATGCCCTGTCCGGACCGTTGCACGGTGGCGCGAATGA
GGCCGTACTACGCCAATTGAAGGCGATTCGTGATTCCGGCAAGTCTGTGGCCGAGTTCGTGCGTGATGCCAAGGAGGATG
GCCAGAAGATCTCCGGCCTTGGCCACCGCGTATACAAGTCGTATGATCCGCGTGCGGCGATTGCCAAGAAGTATCTGGAA
AAGATCATGGAGCGCGAAGATACGCAGAAGCTGCCGTCTGACGAGCGCGCGCTGTTCGCTGTGGCCACCGAGCTTGAAGA
TATTGCGTTGAACGACGAGTATTTCGTATCGCGCAACCTGTATCCGAACGTCGACTTCTACACGGGCTTGATTTATCGGG
CGATCGGCTTCGATCCGGCCATGTTCACCACGCTGTTCGCACTGGGCCGCATTCCCGGTTGGATTGCGCAGTACCGTGAG
ATGCTGGCCGACCCGAATACCAAGATCGGCCGCCCACGCCAGGTCTACACCGGTCCGGTCGAGCGCGATTTCGTGCCGAT
GGACGAGCGCTAA

Upstream 100 bases:

>100_bases
GGCGGTAACACAGAAGACATAAAGTACCGAACACTAGCGTTCGCGAACGCGTGAACGTTAATGTTTGGGGTAAGTGGTTC
ATGAAGAGGAAGGTGCGCGA

Downstream 100 bases:

>100_bases
ATGCTCTGCGTGGTCCGGTGATGCCGGTTTGTTCGATATGTGGGAGCTGATTGCTCGCTACATGATAATTTGCGTAAGAA
ATATTGATTCACCCGAGGGT

Product: citrate synthase I

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MATAQLDVDSNKFNLPVVKASAGPDGIVVSKLRNDGWVTLDPGFLTTAQCESKITYIDGKHSILRYRGYPIEQLCENSDF
LEVAWLLRHGELPSRAEYEQFCADINHKTMVGEDFRTFMGSFPRSAHPMSVLASAINALATFYPDTTDISDTDQLDEAAK
IIMAKARTIVSYIFRRRRDEPMLYPDYARGYVDDFLRMCFAVPYEPFESDPLYVHALGRLLIIHADHEQNCSTSVVRIAG
SAHANLYSAVAAGVNALSGPLHGGANEAVLRQLKAIRDSGKSVAEFVRDAKEDGQKISGLGHRVYKSYDPRAAIAKKYLE
KIMEREDTQKLPSDERALFAVATELEDIALNDEYFVSRNLYPNVDFYTGLIYRAIGFDPAMFTTLFALGRIPGWIAQYRE
MLADPNTKIGRPRQVYTGPVERDFVPMDER

Sequences:

>Translated_430_residues
MATAQLDVDSNKFNLPVVKASAGPDGIVVSKLRNDGWVTLDPGFLTTAQCESKITYIDGKHSILRYRGYPIEQLCENSDF
LEVAWLLRHGELPSRAEYEQFCADINHKTMVGEDFRTFMGSFPRSAHPMSVLASAINALATFYPDTTDISDTDQLDEAAK
IIMAKARTIVSYIFRRRRDEPMLYPDYARGYVDDFLRMCFAVPYEPFESDPLYVHALGRLLIIHADHEQNCSTSVVRIAG
SAHANLYSAVAAGVNALSGPLHGGANEAVLRQLKAIRDSGKSVAEFVRDAKEDGQKISGLGHRVYKSYDPRAAIAKKYLE
KIMEREDTQKLPSDERALFAVATELEDIALNDEYFVSRNLYPNVDFYTGLIYRAIGFDPAMFTTLFALGRIPGWIAQYRE
MLADPNTKIGRPRQVYTGPVERDFVPMDER
>Mature_429_residues
ATAQLDVDSNKFNLPVVKASAGPDGIVVSKLRNDGWVTLDPGFLTTAQCESKITYIDGKHSILRYRGYPIEQLCENSDFL
EVAWLLRHGELPSRAEYEQFCADINHKTMVGEDFRTFMGSFPRSAHPMSVLASAINALATFYPDTTDISDTDQLDEAAKI
IMAKARTIVSYIFRRRRDEPMLYPDYARGYVDDFLRMCFAVPYEPFESDPLYVHALGRLLIIHADHEQNCSTSVVRIAGS
AHANLYSAVAAGVNALSGPLHGGANEAVLRQLKAIRDSGKSVAEFVRDAKEDGQKISGLGHRVYKSYDPRAAIAKKYLEK
IMEREDTQKLPSDERALFAVATELEDIALNDEYFVSRNLYPNVDFYTGLIYRAIGFDPAMFTTLFALGRIPGWIAQYREM
LADPNTKIGRPRQVYTGPVERDFVPMDER

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0372

COG function: function code C; Citrate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the citrate synthase family [H]

Homologues:

Organism=Homo sapiens, GI38327625, Length=384, Percent_Identity=25.78125, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1786939, Length=412, Percent_Identity=44.6601941747573, Blast_Score=370, Evalue=1e-104,
Organism=Escherichia coli, GI1786527, Length=371, Percent_Identity=29.3800539083558, Blast_Score=162, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17555174, Length=362, Percent_Identity=26.7955801104972, Blast_Score=109, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319850, Length=336, Percent_Identity=27.3809523809524, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324328, Length=336, Percent_Identity=27.3809523809524, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6325257, Length=413, Percent_Identity=24.2130750605327, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640126, Length=334, Percent_Identity=28.4431137724551, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24640124, Length=334, Percent_Identity=28.4431137724551, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356863, Length=352, Percent_Identity=26.9886363636364, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: 624 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016142
- InterPro:   IPR016143
- InterPro:   IPR002020
- InterPro:   IPR016141
- InterPro:   IPR019810
- InterPro:   IPR010953 [H]

Pfam domain/function: PF00285 Citrate_synt [H]

EC number: =2.3.3.1 [H]

Molecular weight: Translated: 48282; Mature: 48151

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATAQLDVDSNKFNLPVVKASAGPDGIVVSKLRNDGWVTLDPGFLTTAQCESKITYIDGK
CCCEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCEEEECCCCEEHHHHCCCEEEECCC
HSILRYRGYPIEQLCENSDFLEVAWLLRHGELPSRAEYEQFCADINHKTMVGEDFRTFMG
CCEEEECCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
SFPRSAHPMSVLASAINALATFYPDTTDISDTDQLDEAAKIIMAKARTIVSYIFRRRRDE
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PMLYPDYARGYVDDFLRMCFAVPYEPFESDPLYVHALGRLLIIHADHEQNCSTSVVRIAG
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHEEECCEEEEECCCCCCCCCHHHEECC
SAHANLYSAVAAGVNALSGPLHGGANEAVLRQLKAIRDSGKSVAEFVRDAKEDGQKISGL
CHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GHRVYKSYDPRAAIAKKYLEKIMEREDTQKLPSDERALFAVATELEDIALNDEYFVSRNL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEECCC
YPNVDFYTGLIYRAIGFDPAMFTTLFALGRIPGWIAQYREMLADPNTKIGRPRQVYTGPV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEECCC
ERDFVPMDER
CCCCCCCCCC
>Mature Secondary Structure 
ATAQLDVDSNKFNLPVVKASAGPDGIVVSKLRNDGWVTLDPGFLTTAQCESKITYIDGK
CCEEEECCCCCCCCEEEEECCCCCCEEEEEECCCCEEEECCCCEEHHHHCCCEEEECCC
HSILRYRGYPIEQLCENSDFLEVAWLLRHGELPSRAEYEQFCADINHKTMVGEDFRTFMG
CCEEEECCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
SFPRSAHPMSVLASAINALATFYPDTTDISDTDQLDEAAKIIMAKARTIVSYIFRRRRDE
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PMLYPDYARGYVDDFLRMCFAVPYEPFESDPLYVHALGRLLIIHADHEQNCSTSVVRIAG
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHEEECCEEEEECCCCCCCCCHHHEECC
SAHANLYSAVAAGVNALSGPLHGGANEAVLRQLKAIRDSGKSVAEFVRDAKEDGQKISGL
CHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GHRVYKSYDPRAAIAKKYLEKIMEREDTQKLPSDERALFAVATELEDIALNDEYFVSRNL
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCEEECCC
YPNVDFYTGLIYRAIGFDPAMFTTLFALGRIPGWIAQYREMLADPNTKIGRPRQVYTGPV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCEEECCC
ERDFVPMDER
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]