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The map label for this gene is map [H]

Identifier: 213691495

GI number: 213691495

Start: 671605

End: 672387

Strand: Direct

Name: map [H]

Synonym: Blon_0593

Alternate gene names: 213691495

Gene position: 671605-672387 (Clockwise)

Preceding gene: 213691494

Following gene: 213691496

Centisome position: 23.71

GC content: 62.84

Gene sequence:

>783_bases
ATGATCGAATTGAAGACCCCTCGTGAAATCGAGGAGATGAAGCCCGCCGGCCGTTTCGTCGGCGGCATTCTGAAGGAACT
GCAGGAGACCACCAAGGTGGGCACCAATCTGCTCGAAATCGACGAGTTCGTCCACAAGAAGATCGTGGACCGCAAGGGCG
CCGAATCCTGCTATGTTGACTACGCTCCTGACTTCGGCACCGGCCCGTTCGCCCACTACATCTGCACCTCCGTCAACGAC
GCCGTGCTGCACGGTGTGCCGTACGATTACAGCCTGAAGGACGGCGACCTCGTCTCCCTCGATCTCGCCATCTCCGTGGA
TGGCTGGGTGGCCGATTCCGCCGTCAGCTTCGTGGTCGGCAAAGACCCGGACCCCGAAGACCTGCGCATCATCAAGTGCA
CTGAGGAAGCGCTCGCCGCCGCCATCGACGTGGCCAAGCCCGGCAACCGTCTCGGCGACATCTCCAACACCATTGGCGAC
ATCGCGCGCGAATACGGCTACCCGATCAACCTCGAGTTCGGCGGTCACGGCGTGGGCCACATCATGCACGGCGACCCGCA
CGTACCGAACGACGGCCGCGCCCACCACGGCTACAAGCTGCGCGAAGGCCTGGTCATCGCCATCGAACCATGGTTCCTCA
AGACCACCGACGAGATCTTCCAGGATCCGAAGGACGGCTGGACCCTGCGTGCCTCCGACGGCTCGCGCGGTGCCCACTCC
GAGCACACCATCGCCATCACCGAGAACGGCCCGATCATCTTCACCGATCGCACCAACCTCTGA

Upstream 100 bases:

>100_bases
CTACTAGCGGACCCTAGGCAGACCACGGGTGATGCTCTGGCGGTTGACCCCGGGCTGGGCTAGAGTTGAGAACAAGTCTC
AACAAGGTAGAAAGAACCTC

Downstream 100 bases:

>100_bases
TTGGCGTTTGGCGTATGGCGGGTGCCTGATTGGCCTGTGATGGGCGATCGGCATCTCATCAACCGTCTATATGTTTGCGG
TTTTCCCGCGAATTCGAGAC

Product: methionine aminopeptidase, type I

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MIELKTPREIEEMKPAGRFVGGILKELQETTKVGTNLLEIDEFVHKKIVDRKGAESCYVDYAPDFGTGPFAHYICTSVND
AVLHGVPYDYSLKDGDLVSLDLAISVDGWVADSAVSFVVGKDPDPEDLRIIKCTEEALAAAIDVAKPGNRLGDISNTIGD
IAREYGYPINLEFGGHGVGHIMHGDPHVPNDGRAHHGYKLREGLVIAIEPWFLKTTDEIFQDPKDGWTLRASDGSRGAHS
EHTIAITENGPIIFTDRTNL

Sequences:

>Translated_260_residues
MIELKTPREIEEMKPAGRFVGGILKELQETTKVGTNLLEIDEFVHKKIVDRKGAESCYVDYAPDFGTGPFAHYICTSVND
AVLHGVPYDYSLKDGDLVSLDLAISVDGWVADSAVSFVVGKDPDPEDLRIIKCTEEALAAAIDVAKPGNRLGDISNTIGD
IAREYGYPINLEFGGHGVGHIMHGDPHVPNDGRAHHGYKLREGLVIAIEPWFLKTTDEIFQDPKDGWTLRASDGSRGAHS
EHTIAITENGPIIFTDRTNL
>Mature_260_residues
MIELKTPREIEEMKPAGRFVGGILKELQETTKVGTNLLEIDEFVHKKIVDRKGAESCYVDYAPDFGTGPFAHYICTSVND
AVLHGVPYDYSLKDGDLVSLDLAISVDGWVADSAVSFVVGKDPDPEDLRIIKCTEEALAAAIDVAKPGNRLGDISNTIGD
IAREYGYPINLEFGGHGVGHIMHGDPHVPNDGRAHHGYKLREGLVIAIEPWFLKTTDEIFQDPKDGWTLRASDGSRGAHS
EHTIAITENGPIIFTDRTNL

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI40385867, Length=257, Percent_Identity=30.3501945525292, Blast_Score=125, Evalue=3e-29,
Organism=Homo sapiens, GI164420681, Length=259, Percent_Identity=31.2741312741313, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1786364, Length=259, Percent_Identity=33.976833976834, Blast_Score=147, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71996291, Length=259, Percent_Identity=30.8880308880309, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6323273, Length=249, Percent_Identity=30.9236947791165, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24583427, Length=253, Percent_Identity=32.4110671936759, Blast_Score=130, Evalue=9e-31,
Organism=Drosophila melanogaster, GI21355531, Length=249, Percent_Identity=30.5220883534137, Blast_Score=119, Evalue=2e-27,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 28464; Mature: 28464

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELKTPREIEEMKPAGRFVGGILKELQETTKVGTNLLEIDEFVHKKIVDRKGAESCYVD
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEE
YAPDFGTGPFAHYICTSVNDAVLHGVPYDYSLKDGDLVSLDLAISVDGWVADSAVSFVVG
CCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCCEEEEEEEEEECCEECCCEEEEEEC
KDPDPEDLRIIKCTEEALAAAIDVAKPGNRLGDISNTIGDIAREYGYPINLEFGGHGVGH
CCCCCCCEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCEEE
IMHGDPHVPNDGRAHHGYKLREGLVIAIEPWFLKTTDEIFQDPKDGWTLRASDGSRGAHS
EECCCCCCCCCCCCCCCEEECCCEEEEEECEEECCCHHHHCCCCCCEEEEECCCCCCCCC
EHTIAITENGPIIFTDRTNL
CEEEEEECCCCEEEEECCCC
>Mature Secondary Structure
MIELKTPREIEEMKPAGRFVGGILKELQETTKVGTNLLEIDEFVHKKIVDRKGAESCYVD
CCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEE
YAPDFGTGPFAHYICTSVNDAVLHGVPYDYSLKDGDLVSLDLAISVDGWVADSAVSFVVG
CCCCCCCCHHHHHHHHCCCCHHHCCCCCCCCCCCCCEEEEEEEEEECCEECCCEEEEEEC
KDPDPEDLRIIKCTEEALAAAIDVAKPGNRLGDISNTIGDIAREYGYPINLEFGGHGVGH
CCCCCCCEEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCEEE
IMHGDPHVPNDGRAHHGYKLREGLVIAIEPWFLKTTDEIFQDPKDGWTLRASDGSRGAHS
EECCCCCCCCCCCCCCCEEECCCEEEEEECEEECCCHHHHCCCCCCEEEEECCCCCCCCC
EHTIAITENGPIIFTDRTNL
CEEEEEECCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]