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The map label for this gene is lepB [H]

Identifier: 213691334

GI number: 213691334

Start: 486574

End: 487413

Strand: Direct

Name: lepB [H]

Synonym: Blon_0421

Alternate gene names: 213691334

Gene position: 486574-487413 (Clockwise)

Preceding gene: 213691333

Following gene: 213691335

Centisome position: 17.18

GC content: 61.31

Gene sequence:

>840_bases
ATGCAGGACGATCAGGATAACGGCGAATTCCCGGTTTCCGACAATCCGGAGAGCAACCAGACCTCGTATGATGACGAGGC
CGATGCCCGCGATTCCCGCACGTTCCAAGTCGCCGACCACGGCATCGCCCTGTCCCCGGTTCCCCCGGCACCGGCGCGCC
CTGCGCACGCCGCTTCTTCCGCTGGCGCGAATGCCGCGGCAGCATCATCGATGGATGATGACCACTTCACCCTACGCGAC
TTTTTCCTGTGGTGCGGCGTTCCCGTGCTTATCGTGCTGCTGATTCGCATTTTCGCCGTCGGCTTTTACGAGATTCCTTC
GCGCTCGATGATGGACACCATGGTGCCCGGCGATCGCGTGGCGACCAGCAAGCTCACCCCCAAGATCTTCGATCTGCAGC
GCGGCGACGTCGTGGTATTCAAAGATCCCAACAACTGGTTGAACGAGGAGCAGAGCAGCGCTCTCGGTGGCGGGTACCTC
ATCAAGCGACTGATCGGACTGCCCGGTGACGTGGTCGAATGCAAGGGCGCGGGCCAGCCGGTGACCATCAACGGCGTGGC
CATCAATGAGACCTCCTACATTCGCCCCGGCGTGGATCCGAGCGCCTTCCCGTTCTCGGTAACCGTGACCGAGGACCACG
TGTTCGTCATGGGCGACAATCGCGCCAATTCCGCCGACTCCCGCTATCATCAGGATGACGGCGATCGCGGCTTGGTTCCC
ATCTCCGATGTGGTCGGAGTCGGAATCGCGAGATACTGGCCGCTTGACCGGCTTGGTGCGATTGATGACTACCACGAAGT
CTTCAAGGACGTGCCTGACGCTTCCGGCTCAAATTCCTGA

Upstream 100 bases:

>100_bases
CGGAACCGTTTCGGTTTCGGGCTGTTTCCGTATTTTCCACGTATGATGGACGGGCGCCGGCACCCCTCATATCCGGCAGC
ATGAATCGCGAGGAGATGGT

Downstream 100 bases:

>100_bases
GTCTTCGTTGAACCGTGTGAGTCTTTGAACTGATTGAGTTCCGGGCCGTCTGAATCCTGAGCCATATGAATCCTAACCAT
TGTGAGACGATGGGAGCCGC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MQDDQDNGEFPVSDNPESNQTSYDDEADARDSRTFQVADHGIALSPVPPAPARPAHAASSAGANAAAASSMDDDHFTLRD
FFLWCGVPVLIVLLIRIFAVGFYEIPSRSMMDTMVPGDRVATSKLTPKIFDLQRGDVVVFKDPNNWLNEEQSSALGGGYL
IKRLIGLPGDVVECKGAGQPVTINGVAINETSYIRPGVDPSAFPFSVTVTEDHVFVMGDNRANSADSRYHQDDGDRGLVP
ISDVVGVGIARYWPLDRLGAIDDYHEVFKDVPDASGSNS

Sequences:

>Translated_279_residues
MQDDQDNGEFPVSDNPESNQTSYDDEADARDSRTFQVADHGIALSPVPPAPARPAHAASSAGANAAAASSMDDDHFTLRD
FFLWCGVPVLIVLLIRIFAVGFYEIPSRSMMDTMVPGDRVATSKLTPKIFDLQRGDVVVFKDPNNWLNEEQSSALGGGYL
IKRLIGLPGDVVECKGAGQPVTINGVAINETSYIRPGVDPSAFPFSVTVTEDHVFVMGDNRANSADSRYHQDDGDRGLVP
ISDVVGVGIARYWPLDRLGAIDDYHEVFKDVPDASGSNS
>Mature_279_residues
MQDDQDNGEFPVSDNPESNQTSYDDEADARDSRTFQVADHGIALSPVPPAPARPAHAASSAGANAAAASSMDDDHFTLRD
FFLWCGVPVLIVLLIRIFAVGFYEIPSRSMMDTMVPGDRVATSKLTPKIFDLQRGDVVVFKDPNNWLNEEQSSALGGGYL
IKRLIGLPGDVVECKGAGQPVTINGVAINETSYIRPGVDPSAFPFSVTVTEDHVFVMGDNRANSADSRYHQDDGDRGLVP
ISDVVGVGIARYWPLDRLGAIDDYHEVFKDVPDASGSNS

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056
- InterPro:   IPR019533 [H]

Pfam domain/function: PF00717 Peptidase_S24; PF10502 Peptidase_S26 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 30117; Mature: 30117

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDDQDNGEFPVSDNPESNQTSYDDEADARDSRTFQVADHGIALSPVPPAPARPAHAASS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCCCHHHC
AGANAAAASSMDDDHFTLRDFFLWCGVPVLIVLLIRIFAVGFYEIPSRSMMDTMVPGDRV
CCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCE
ATSKLTPKIFDLQRGDVVVFKDPNNWLNEEQSSALGGGYLIKRLIGLPGDVVECKGAGQP
ECCCCCCHHEECCCCCEEEEECCCHHHCHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCC
VTINGVAINETSYIRPGVDPSAFPFSVTVTEDHVFVMGDNRANSADSRYHQDDGDRGLVP
EEEEEEEECCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCEE
ISDVVGVGIARYWPLDRLGAIDDYHEVFKDVPDASGSNS
HHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQDDQDNGEFPVSDNPESNQTSYDDEADARDSRTFQVADHGIALSPVPPAPARPAHAASS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCCCCCHHHC
AGANAAAASSMDDDHFTLRDFFLWCGVPVLIVLLIRIFAVGFYEIPSRSMMDTMVPGDRV
CCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCE
ATSKLTPKIFDLQRGDVVVFKDPNNWLNEEQSSALGGGYLIKRLIGLPGDVVECKGAGQP
ECCCCCCHHEECCCCCEEEEECCCHHHCHHHHHHCCHHHHHHHHHCCCCCEEEECCCCCC
VTINGVAINETSYIRPGVDPSAFPFSVTVTEDHVFVMGDNRANSADSRYHQDDGDRGLVP
EEEEEEEECCCCCCCCCCCCCCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCCEE
ISDVVGVGIARYWPLDRLGAIDDYHEVFKDVPDASGSNS
HHHHHHHHHHHHCCHHHHCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]