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The map label for this gene is mtnN [H]

Identifier: 213691275

GI number: 213691275

Start: 416829

End: 417542

Strand: Direct

Name: mtnN [H]

Synonym: Blon_0359

Alternate gene names: 213691275

Gene position: 416829-417542 (Clockwise)

Preceding gene: 213691274

Following gene: 213691276

Centisome position: 14.71

GC content: 61.34

Gene sequence:

>714_bases
ATGGGTATGAAAACTGTAGCTATTATTGGCGCATTGGATGAGGAAGTGGCGCTGATCGCCAAATCGCTCACGCATGTGAC
GCACACCGCCAAGGGCAGCCTTGACATCGTGTCCGGCACGGTCGACTCCTTTGGTTCTGACGTCATCAAGGTTGCCGCAA
CGGTAGGCGGCATGGGACTGGTCAATGCGGCCGCCACCACGCAGCTGCTGATTGACGAGTTCGCCCCGGACGCCGTGATT
TTCAGCGGCATCGCCGGCAACCTCAACACCCACCTGCACATCAACGACGTGGTGCTCGGCGGCACCCTGCGCTACCTCGA
CACTGACATGCGGCTCGTAGGCCAGTGGAAGCCCGGCACTGCGGACGCTCCGGTGGAGGAATTCCACTCTGATGACCGTC
TGCTGGAAGTTGCCGACGAGGCGCTTGCCAATGCGGGCATTACCCACATCACCGGCATCATCGCCTCCGGCAACTACTTC
GTGGACACGCCCCAAAAGGCCGAGGAGGTCATCCGACTCACCGGGGCTGACGCCGTGGAGATGGAAGGAGCCGCCGTGGC
ACAGGTCGCCGCCCGCAATGACGTGCCGGCACTGGTGATTCGTGCCCTTTCCGACAACGCCGACACTGATTACGAGGTAT
TCAAGGAGTTCGACATCTCCGAATACGCCGACACCGCCGCCCGTCTGGCCGTCGATATCGTCAAGCGCCTGTAA

Upstream 100 bases:

>100_bases
GCAGGAGCAATGCAACGAAACGTCTCTACCCCTCAGCCTGCCATTCGGCGGCCACCTCCCCTGACATGGGAGTCGAAAGC
GTTGTGAAAGGAACTTACGT

Downstream 100 bases:

>100_bases
TCGGCGGGCTGGCCCATCTCACCATCCACGCTTTGGATATGATGACCACTATATGAGCGCTTTCAAACTATTGCTTATAA
CCTGAGTCATACTCGGTGTT

Product: Methylthioadenosine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MGMKTVAIIGALDEEVALIAKSLTHVTHTAKGSLDIVSGTVDSFGSDVIKVAATVGGMGLVNAAATTQLLIDEFAPDAVI
FSGIAGNLNTHLHINDVVLGGTLRYLDTDMRLVGQWKPGTADAPVEEFHSDDRLLEVADEALANAGITHITGIIASGNYF
VDTPQKAEEVIRLTGADAVEMEGAAVAQVAARNDVPALVIRALSDNADTDYEVFKEFDISEYADTAARLAVDIVKRL

Sequences:

>Translated_237_residues
MGMKTVAIIGALDEEVALIAKSLTHVTHTAKGSLDIVSGTVDSFGSDVIKVAATVGGMGLVNAAATTQLLIDEFAPDAVI
FSGIAGNLNTHLHINDVVLGGTLRYLDTDMRLVGQWKPGTADAPVEEFHSDDRLLEVADEALANAGITHITGIIASGNYF
VDTPQKAEEVIRLTGADAVEMEGAAVAQVAARNDVPALVIRALSDNADTDYEVFKEFDISEYADTAARLAVDIVKRL
>Mature_236_residues
GMKTVAIIGALDEEVALIAKSLTHVTHTAKGSLDIVSGTVDSFGSDVIKVAATVGGMGLVNAAATTQLLIDEFAPDAVIF
SGIAGNLNTHLHINDVVLGGTLRYLDTDMRLVGQWKPGTADAPVEEFHSDDRLLEVADEALANAGITHITGIIASGNYFV
DTPQKAEEVIRLTGADAVEMEGAAVAQVAARNDVPALVIRALSDNADTDYEVFKEFDISEYADTAARLAVDIVKRL

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=234, Percent_Identity=30.3418803418803, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 24932; Mature: 24801

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMKTVAIIGALDEEVALIAKSLTHVTHTAKGSLDIVSGTVDSFGSDVIKVAATVGGMGL
CCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHH
VNAAATTQLLIDEFAPDAVIFSGIAGNLNTHLHINDVVLGGTLRYLDTDMRLVGQWKPGT
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEEEECCCCEECCCCCCEEECCCCCC
ADAPVEEFHSDDRLLEVADEALANAGITHITGIIASGNYFVDTPQKAEEVIRLTGADAVE
CCCCHHHHCCCCHHHHHHHHHHHHCCHHHHHEEEECCCEEECCCHHHHHHHHHCCCCCEE
MEGAAVAQVAARNDVPALVIRALSDNADTDYEVFKEFDISEYADTAARLAVDIVKRL
CCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
GMKTVAIIGALDEEVALIAKSLTHVTHTAKGSLDIVSGTVDSFGSDVIKVAATVGGMGL
CCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHCCCHH
VNAAATTQLLIDEFAPDAVIFSGIAGNLNTHLHINDVVLGGTLRYLDTDMRLVGQWKPGT
HHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEEEECCCCEECCCCCCEEECCCCCC
ADAPVEEFHSDDRLLEVADEALANAGITHITGIIASGNYFVDTPQKAEEVIRLTGADAVE
CCCCHHHHCCCCHHHHHHHHHHHHCCHHHHHEEEECCCEEECCCHHHHHHHHHCCCCCEE
MEGAAVAQVAARNDVPALVIRALSDNADTDYEVFKEFDISEYADTAARLAVDIVKRL
CCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA