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The map label for this gene is lysC [H]

Identifier: 213691086

GI number: 213691086

Start: 194088

End: 194654

Strand: Direct

Name: lysC [H]

Synonym: Blon_0165

Alternate gene names: 213691086

Gene position: 194088-194654 (Clockwise)

Preceding gene: 213691085

Following gene: 213691088

Centisome position: 6.85

GC content: 62.26

Gene sequence:

>567_bases
ATGACTGAAGAAGAAGCGAAATCCATGGGCGACCTGTTCCCTGACCTAGGCCCCGAGGCGCCGGTGATTTCCGGCATTGC
CCACGACCGTTCCGAGGCGCTGGCCACCGTGCGTGGCGTGCCGAACGAGCCGGGTATGGCCGCCAAGGTGTTCACCGAGC
TGGCCACCGCCGGCGTGAACGTGGACATGATCGTGCAGGCCGGCGCATCCGTTGGCACTGCGGACATCTCCTTCACCGTG
CCCGAATCGGCCGTCAAGCAGGTGCAGAACACGCTGCTCGACAAGCAGGAAGTGCTGGGTTACCACTCCTTTGATGTGAA
CACCAACGTCGGCAAGGTAGCCGTGGTGGGTGTTGGCATGAAGACCCACGCCGGTCTGGCTGCCAAGTTCTTCCAGGCCC
TGAGCGATGAGGGCATCAACGTGCTGATGATTTCCACTTCCGAGATTCGCATCGCCGCACTCGTGCCGCTCGATCAGCTC
AACGATGCCGTCAAGGCGCTGCACACCGCATACGGTCTCGATGCCGATCAGATCGAAGCCGTGGTGTACGGCGGTACTGG
CCGCTGA

Upstream 100 bases:

>100_bases
GTGCCTGACGGCATTGACCCGCGCACGCTGCCGAACCTCGACTGAGCGCGGCTACAGCGAACAATAATCGTAAGTAATTT
CAACCAAGACAAGGCAAGAC

Downstream 100 bases:

>100_bases
GCCACTGAGCCGCGTTTTTGCGGTATATACGACGAAAGCCCTCCTCACGGAGGGCTTTTGCGATTTTAACGAGTTTCAAC
TACTTCTTGGTGATGTAGCC

Product: amino acid-binding ACT domain protein

Products: NA

Alternate protein names: Aspartate kinase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MTEEEAKSMGDLFPDLGPEAPVISGIAHDRSEALATVRGVPNEPGMAAKVFTELATAGVNVDMIVQAGASVGTADISFTV
PESAVKQVQNTLLDKQEVLGYHSFDVNTNVGKVAVVGVGMKTHAGLAAKFFQALSDEGINVLMISTSEIRIAALVPLDQL
NDAVKALHTAYGLDADQIEAVVYGGTGR

Sequences:

>Translated_188_residues
MTEEEAKSMGDLFPDLGPEAPVISGIAHDRSEALATVRGVPNEPGMAAKVFTELATAGVNVDMIVQAGASVGTADISFTV
PESAVKQVQNTLLDKQEVLGYHSFDVNTNVGKVAVVGVGMKTHAGLAAKFFQALSDEGINVLMISTSEIRIAALVPLDQL
NDAVKALHTAYGLDADQIEAVVYGGTGR
>Mature_187_residues
TEEEAKSMGDLFPDLGPEAPVISGIAHDRSEALATVRGVPNEPGMAAKVFTELATAGVNVDMIVQAGASVGTADISFTVP
ESAVKQVQNTLLDKQEVLGYHSFDVNTNVGKVAVVGVGMKTHAGLAAKFFQALSDEGINVLMISTSEIRIAALVPLDQLN
DAVKALHTAYGLDADQIEAVVYGGTGR

Specific function: Catalyzes 2 nonconsecutive reactions in the common biosynthetic pathway leading from Asp to diaminopimelate and Lys, to Met, and to Thr and Ile. [C]

COG id: COG0527

COG function: function code E; Aspartokinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ACT domains [H]

Homologues:

Organism=Escherichia coli, GI1786183, Length=169, Percent_Identity=31.3609467455621, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001048
- InterPro:   IPR005260
- InterPro:   IPR001341
- InterPro:   IPR018042 [H]

Pfam domain/function: PF00696 AA_kinase; PF01842 ACT [H]

EC number: =2.7.2.4 [H]

Molecular weight: Translated: 19566; Mature: 19435

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEEAKSMGDLFPDLGPEAPVISGIAHDRSEALATVRGVPNEPGMAAKVFTELATAGVN
CCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
VDMIVQAGASVGTADISFTVPESAVKQVQNTLLDKQEVLGYHSFDVNTNVGKVAVVGVGM
EEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHCHHHHHCEEECCCCCCCCEEEEEECCC
KTHAGLAAKFFQALSDEGINVLMISTSEIRIAALVPLDQLNDAVKALHTAYGLDADQIEA
HHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHCCCHHHEEE
VVYGGTGR
EEECCCCC
>Mature Secondary Structure 
TEEEAKSMGDLFPDLGPEAPVISGIAHDRSEALATVRGVPNEPGMAAKVFTELATAGVN
CHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCC
VDMIVQAGASVGTADISFTVPESAVKQVQNTLLDKQEVLGYHSFDVNTNVGKVAVVGVGM
EEEEEECCCCCCCCEEEEECCHHHHHHHHHHHHCHHHHHCEEECCCCCCCCEEEEEECCC
KTHAGLAAKFFQALSDEGINVLMISTSEIRIAALVPLDQLNDAVKALHTAYGLDADQIEA
HHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECCHHHHHHHHHHHHHHHCCCHHHEEE
VVYGGTGR
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12840036 [H]