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The map label for this gene is celR [H]

Identifier: 213691059

GI number: 213691059

Start: 162802

End: 163836

Strand: Reverse

Name: celR [H]

Synonym: Blon_0138

Alternate gene names: 213691059

Gene position: 163836-162802 (Counterclockwise)

Preceding gene: 213691060

Following gene: 213691058

Centisome position: 5.78

GC content: 62.42

Gene sequence:

>1035_bases
ATGACCAAGGCAAGCATTCAGGCAGTGGCCCGCGAGGCCGGCGTTTCCGTATCCACGGTGTCCCGAACCTTCGCCAAGCC
GGATCTGGTGCTTCCCGAGACTCGAGACCGAGTGATGGCCGCGGCCGAAAAGCTCGACTACTCAGTCTCTCGCTCGGCCG
CCGCCCTGAAATCCGGCCAATCGTTCCGTATCGCATTGCTTGCCAGCGAGACCATCGCCAGCTGGTTCAATTCGAACATC
TTCGCCGGCCTTGACTCGGCGCTGCGCCCCTCCGGCTACGACACCGTGCCCTACCCCATGCGCAACGCCGCCGAGCGCCA
CGACTTCTTTGCGGATTTGCCCGTGCGGCGCAATGCGGATGCGGTGATTGTCAGCTCCTTCGACATCGAACCGGCTGAGG
TGGAGCGACTGAAGCATATGCACGTGCCGATTGTCGGCATCAACATCCCCTCCACCGATGGGTTCGACGCAGGCGTGAGC
ATTGATGATTACGCCGCCACACGTTCGGCTATCGAGCACCTGATTGCACTCGGCCACCGGCAGATCGCGTTCGTCGGCAG
CGCACCGACCGAAACCAATATGCGCTACAGTACCGAGGCTCGTTTGCAGGGTGTCATTGATGCCGCTGCCGCCCATCCGG
GGATCGAGCTAACGCCCCTGAGCATTCAACGCGGTCTTGGCGAAAGCAACGCGGCATTGAACGCCGTACTGAACGCCTCC
CCCAGCATCACCGCCTTCTGTTTTGAGGATGATGAAATGGCCGCGCCCGTGCTGTATCGCCTGCGTCAATACGGGCGGCG
GGTACCTCAGGACATTTCCATCATCGGCTTCGACGATTCCACCCTGTCCGCCGCCGTGGGACTGACCACGCTGCATCAGG
ACCCGTTCGCAATGGGCGCGACTGCCGGGCACATGGTATTGGATGCCATTGCCGGCAAGTCAATCGAACCGGCATTCGTA
CGGCCGGACACTCCGCTAATACTGCGCGAAACCACCACGCCGCCTGCCGCGACAGCAGCGCCCGCGCAGGCGTGA

Upstream 100 bases:

>100_bases
AGCCCCTCGTAATCGAGATAGCCGAAGACGACGACTTGTTATGGGCATGTTATCGTTGTCATGACAATGATTGTTCGCGA
CGGCGAAGGAGCGACGGCAT

Downstream 100 bases:

>100_bases
CCACGTTACCACCGCAAAACGCCGATAAATCGATTGTTGCATGCGTAATTCACATGATATCGTTGTCATCATCAATACAA
CGGTTGGGCCTTCACACAGC

Product: regulatory protein, LacI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTKASIQAVAREAGVSVSTVSRTFAKPDLVLPETRDRVMAAAEKLDYSVSRSAAALKSGQSFRIALLASETIASWFNSNI
FAGLDSALRPSGYDTVPYPMRNAAERHDFFADLPVRRNADAVIVSSFDIEPAEVERLKHMHVPIVGINIPSTDGFDAGVS
IDDYAATRSAIEHLIALGHRQIAFVGSAPTETNMRYSTEARLQGVIDAAAAHPGIELTPLSIQRGLGESNAALNAVLNAS
PSITAFCFEDDEMAAPVLYRLRQYGRRVPQDISIIGFDDSTLSAAVGLTTLHQDPFAMGATAGHMVLDAIAGKSIEPAFV
RPDTPLILRETTTPPAATAAPAQA

Sequences:

>Translated_344_residues
MTKASIQAVAREAGVSVSTVSRTFAKPDLVLPETRDRVMAAAEKLDYSVSRSAAALKSGQSFRIALLASETIASWFNSNI
FAGLDSALRPSGYDTVPYPMRNAAERHDFFADLPVRRNADAVIVSSFDIEPAEVERLKHMHVPIVGINIPSTDGFDAGVS
IDDYAATRSAIEHLIALGHRQIAFVGSAPTETNMRYSTEARLQGVIDAAAAHPGIELTPLSIQRGLGESNAALNAVLNAS
PSITAFCFEDDEMAAPVLYRLRQYGRRVPQDISIIGFDDSTLSAAVGLTTLHQDPFAMGATAGHMVLDAIAGKSIEPAFV
RPDTPLILRETTTPPAATAAPAQA
>Mature_343_residues
TKASIQAVAREAGVSVSTVSRTFAKPDLVLPETRDRVMAAAEKLDYSVSRSAAALKSGQSFRIALLASETIASWFNSNIF
AGLDSALRPSGYDTVPYPMRNAAERHDFFADLPVRRNADAVIVSSFDIEPAEVERLKHMHVPIVGINIPSTDGFDAGVSI
DDYAATRSAIEHLIALGHRQIAFVGSAPTETNMRYSTEARLQGVIDAAAAHPGIELTPLSIQRGLGESNAALNAVLNASP
SITAFCFEDDEMAAPVLYRLRQYGRRVPQDISIIGFDDSTLSAAVGLTTLHQDPFAMGATAGHMVLDAIAGKSIEPAFVR
PDTPLILRETTTPPAATAAPAQA

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=336, Percent_Identity=29.4642857142857, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1790369, Length=341, Percent_Identity=29.0322580645161, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI1786540, Length=357, Percent_Identity=27.7310924369748, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788474, Length=351, Percent_Identity=27.0655270655271, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790194, Length=332, Percent_Identity=26.5060240963855, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI48994940, Length=324, Percent_Identity=24.3827160493827, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790715, Length=322, Percent_Identity=26.3975155279503, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789202, Length=289, Percent_Identity=28.719723183391, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789068, Length=278, Percent_Identity=27.3381294964029, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787906, Length=295, Percent_Identity=27.1186440677966, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787580, Length=323, Percent_Identity=25.077399380805, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790689, Length=255, Percent_Identity=27.4509803921569, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 36630; Mature: 36499

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKASIQAVAREAGVSVSTVSRTFAKPDLVLPETRDRVMAAAEKLDYSVSRSAAALKSGQ
CCHHHHHHHHHHHCCCHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SFRIALLASETIASWFNSNIFAGLDSALRPSGYDTVPYPMRNAAERHDFFADLPVRRNAD
CEEEEEEEHHHHHHHHCCCHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
AVIVSSFDIEPAEVERLKHMHVPIVGINIPSTDGFDAGVSIDDYAATRSAIEHLIALGHR
EEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
QIAFVGSAPTETNMRYSTEARLQGVIDAAAAHPGIELTPLSIQRGLGESNAALNAVLNAS
EEEEEECCCCCCCCEECHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCHHHHHEECCC
PSITAFCFEDDEMAAPVLYRLRQYGRRVPQDISIIGFDDSTLSAAVGLTTLHQDPFAMGA
CCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCC
TAGHMVLDAIAGKSIEPAFVRPDTPLILRETTTPPAATAAPAQA
CHHHHHHHHHCCCCCCCCEECCCCCEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
TKASIQAVAREAGVSVSTVSRTFAKPDLVLPETRDRVMAAAEKLDYSVSRSAAALKSGQ
CHHHHHHHHHHHCCCHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SFRIALLASETIASWFNSNIFAGLDSALRPSGYDTVPYPMRNAAERHDFFADLPVRRNAD
CEEEEEEEHHHHHHHHCCCHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
AVIVSSFDIEPAEVERLKHMHVPIVGINIPSTDGFDAGVSIDDYAATRSAIEHLIALGHR
EEEEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
QIAFVGSAPTETNMRYSTEARLQGVIDAAAAHPGIELTPLSIQRGLGESNAALNAVLNAS
EEEEEECCCCCCCCEECHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCHHHHHEECCC
PSITAFCFEDDEMAAPVLYRLRQYGRRVPQDISIIGFDDSTLSAAVGLTTLHQDPFAMGA
CCEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCC
TAGHMVLDAIAGKSIEPAFVRPDTPLILRETTTPPAATAAPAQA
CHHHHHHHHHCCCCCCCCEECCCCCEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]