BacMap

Definition	Bifidobacterium longum subsp. infantis ATCC 15697, complete genome.
Accession	NC_011593
Length	2,832,748

Click here to switch to the map view.

The map label for this gene is braF [H]

Identifier: 213691028

GI number: 213691028

Start: 128297

End: 129109

Strand: Direct

Name: braF [H]

Synonym: Blon_0107

Alternate gene names: 213691028

Gene position: 128297-129109 (Clockwise)

Preceding gene: 213691027

Following gene: 213691029

Centisome position: 4.53

GC content: 61.13

Gene sequence:

>813_bases
ATGAAGGCCGAGATCGCCAGGGAGCGCCAGGAGCTTGCGAGCCAGCTCGCGACCCTGGACGCCCAGGGCGGCCAATGGAA
CGACTACCTCGAAATCCGTGGATTGCATGTCGAATTCGACGGGTTCGTGGCGGTCAAGGATATCGACCTGACCGTCATGC
ACGGTGATCTGAGGTTCCTGATCGGTCCGAACGGCGCCGGGAAGACCACGATCATCGATGCCATCACCGGACTGGTGCCG
GCCGCAGGCTCGGCCATGTTTGGAGGGGAGGAGCTTATCGGACGCAAGCCGAACGATATCGTCCGGCTGGGGGTCGGCCG
CACCTTCCAGACGGCCTCCGTCGTGGAAGAGCTGTCCGTGCTGCAGAATCTGCAGCTCGCCGAAGGCCTGCACAAGAAGA
TGTCGGAATTATTCAGAAGAACCGAGGGAGCGTCGCGCAACATCCAGAGCATCATGGAAGTGTGCGGTCTCGTCGGCGAT
GCGGATAAGACGGCGGGTATTCTGCCGCACGGCAAGAAGCAGTGGCTGGAGATCGGCATGCTGCTCGTGCAGGACGCGCG
TCTGCTTCTTCTCGATGAACCGGTCGCCGGCATGACGCCGGCGGAACGTCAGGCCACCGGTGAACTGCTCACGCGCATCA
GCCGCAATCGCACGGTCGTCATCGTCGAACACGATATGGATTTCATGCGTCAATTCGCCGACTCGGTCACCGTGCTCAAT
CAGGGGCGGATCCTCGCCGAAGGCAGCGTCGAGGACATCCAGAACAACGAGGAAGTGGTCAGAATCTACCTTGGCGGAGG
AGAAGATCGATGA

Upstream 100 bases:

>100_bases
CGACGAAAACAAGACCGAGGGCGCCGAGCTGGATCAGCTGCGCGATGAGATGCGCAGGATGCGCGATGAAGCCAGACGCT
TCCGCGATGAGGCCGCCAGG

Downstream 100 bases:

>100_bases
TGGCAGAGAACATGTTGGAGATCAGGGGGTTAAGCACAGGCTATGGCAAGGTGTCCGTGGTCAACGACATCGACGTGTCC
GTCCGCCCCGGTGAGTGGGT

Product: ABC transporter

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MKAEIARERQELASQLATLDAQGGQWNDYLEIRGLHVEFDGFVAVKDIDLTVMHGDLRFLIGPNGAGKTTIIDAITGLVP
AAGSAMFGGEELIGRKPNDIVRLGVGRTFQTASVVEELSVLQNLQLAEGLHKKMSELFRRTEGASRNIQSIMEVCGLVGD
ADKTAGILPHGKKQWLEIGMLLVQDARLLLLDEPVAGMTPAERQATGELLTRISRNRTVVIVEHDMDFMRQFADSVTVLN
QGRILAEGSVEDIQNNEEVVRIYLGGGEDR

Sequences:

>Translated_270_residues
MKAEIARERQELASQLATLDAQGGQWNDYLEIRGLHVEFDGFVAVKDIDLTVMHGDLRFLIGPNGAGKTTIIDAITGLVP
AAGSAMFGGEELIGRKPNDIVRLGVGRTFQTASVVEELSVLQNLQLAEGLHKKMSELFRRTEGASRNIQSIMEVCGLVGD
ADKTAGILPHGKKQWLEIGMLLVQDARLLLLDEPVAGMTPAERQATGELLTRISRNRTVVIVEHDMDFMRQFADSVTVLN
QGRILAEGSVEDIQNNEEVVRIYLGGGEDR
>Mature_270_residues
MKAEIARERQELASQLATLDAQGGQWNDYLEIRGLHVEFDGFVAVKDIDLTVMHGDLRFLIGPNGAGKTTIIDAITGLVP
AAGSAMFGGEELIGRKPNDIVRLGVGRTFQTASVVEELSVLQNLQLAEGLHKKMSELFRRTEGASRNIQSIMEVCGLVGD
ADKTAGILPHGKKQWLEIGMLLVQDARLLLLDEPVAGMTPAERQATGELLTRISRNRTVVIVEHDMDFMRQFADSVTVLN
QGRILAEGSVEDIQNNEEVVRIYLGGGEDR

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG4674

COG function: function code R; Uncharacterized ABC-type transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI116734710, Length=209, Percent_Identity=30.1435406698565, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI105990541, Length=216, Percent_Identity=27.7777777777778, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI27881501, Length=214, Percent_Identity=28.9719626168224, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI30795238, Length=214, Percent_Identity=28.9719626168224, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI31657092, Length=211, Percent_Identity=29.8578199052133, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI45446740, Length=211, Percent_Identity=27.9620853080569, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI47078218, Length=211, Percent_Identity=27.4881516587678, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI150417984, Length=255, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI21536376, Length=214, Percent_Identity=26.6355140186916, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI27436953, Length=233, Percent_Identity=26.1802575107296, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI27262624, Length=226, Percent_Identity=26.9911504424779, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI27262626, Length=226, Percent_Identity=26.9911504424779, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI153792144, Length=228, Percent_Identity=27.6315789473684, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI62526033, Length=209, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI171184400, Length=231, Percent_Identity=25.1082251082251, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI156105685, Length=218, Percent_Identity=28.4403669724771, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI27477115, Length=232, Percent_Identity=26.2931034482759, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789864, Length=248, Percent_Identity=36.6935483870968, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1790525, Length=241, Percent_Identity=29.4605809128631, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1790544, Length=245, Percent_Identity=30.6122448979592, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787792, Length=230, Percent_Identity=28.695652173913, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994943, Length=229, Percent_Identity=30.5676855895196, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87081782, Length=227, Percent_Identity=28.6343612334802, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786803, Length=228, Percent_Identity=25, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788897, Length=233, Percent_Identity=28.3261802575107, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790467, Length=204, Percent_Identity=29.4117647058824, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788210, Length=223, Percent_Identity=26.9058295964126, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1790190, Length=229, Percent_Identity=25.764192139738, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI48995001, Length=244, Percent_Identity=28.2786885245902, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788225, Length=244, Percent_Identity=28.6885245901639, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789593, Length=238, Percent_Identity=28.1512605042017, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788472, Length=219, Percent_Identity=26.027397260274, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788450, Length=231, Percent_Identity=29.4372294372294, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786398, Length=215, Percent_Identity=26.5116279069767, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789991, Length=219, Percent_Identity=26.9406392694064, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787370, Length=255, Percent_Identity=26.6666666666667, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87081791, Length=236, Percent_Identity=30.0847457627119, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786872, Length=196, Percent_Identity=27.5510204081633, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87081709, Length=230, Percent_Identity=25.6521739130435, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789672, Length=244, Percent_Identity=27.0491803278689, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1786253, Length=224, Percent_Identity=29.9107142857143, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082268, Length=226, Percent_Identity=27.4336283185841, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1786563, Length=216, Percent_Identity=28.7037037037037, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786345, Length=245, Percent_Identity=25.7142857142857, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787089, Length=229, Percent_Identity=26.6375545851528, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790162, Length=235, Percent_Identity=24.6808510638298, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788761, Length=227, Percent_Identity=27.7533039647577, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787029, Length=245, Percent_Identity=23.6734693877551, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787548, Length=243, Percent_Identity=26.3374485596708, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789586, Length=243, Percent_Identity=26.3374485596708, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788506, Length=224, Percent_Identity=26.3392857142857, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789032, Length=253, Percent_Identity=23.7154150197628, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1787712, Length=231, Percent_Identity=25.5411255411255, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87081834, Length=212, Percent_Identity=23.1132075471698, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=232, Percent_Identity=28.448275862069, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71983516, Length=232, Percent_Identity=28.448275862069, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71983510, Length=232, Percent_Identity=28.448275862069, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17510237, Length=236, Percent_Identity=29.2372881355932, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17565586, Length=207, Percent_Identity=26.0869565217391, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI115533608, Length=204, Percent_Identity=29.9019607843137, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221512771, Length=249, Percent_Identity=27.3092369477912, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24643674, Length=221, Percent_Identity=26.2443438914027, Blast_Score=84, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24666092, Length=222, Percent_Identity=25.6756756756757, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573571, Length=223, Percent_Identity=27.3542600896861, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI28573573, Length=229, Percent_Identity=26.6375545851528, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24648314, Length=228, Percent_Identity=23.6842105263158, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007184, Length=213, Percent_Identity=24.8826291079812, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI221500365, Length=213, Percent_Identity=24.8826291079812, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28574533, Length=198, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 29545; Mature: 29545

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAEIARERQELASQLATLDAQGGQWNDYLEIRGLHVEFDGFVAVKDIDLTVMHGDLRFL
CCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCEEEEEEEEEEEEECCEEEE
IGPNGAGKTTIIDAITGLVPAAGSAMFGGEELIGRKPNDIVRLGVGRTFQTASVVEELSV
ECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHH
LQNLQLAEGLHKKMSELFRRTEGASRNIQSIMEVCGLVGDADKTAGILPHGKKQWLEIGM
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LLVQDARLLLLDEPVAGMTPAERQATGELLTRISRNRTVVIVEHDMDFMRQFADSVTVLN
HHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEECC
QGRILAEGSVEDIQNNEEVVRIYLGGGEDR
CCEEEECCCHHHHCCCCEEEEEEECCCCCC
>Mature Secondary Structure
MKAEIARERQELASQLATLDAQGGQWNDYLEIRGLHVEFDGFVAVKDIDLTVMHGDLRFL
CCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCEEEEEEEEEEEEECCEEEE
IGPNGAGKTTIIDAITGLVPAAGSAMFGGEELIGRKPNDIVRLGVGRTFQTASVVEELSV
ECCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCEEEECCCCCHHHHHHHHHHHH
LQNLQLAEGLHKKMSELFRRTEGASRNIQSIMEVCGLVGDADKTAGILPHGKKQWLEIGM
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LLVQDARLLLLDEPVAGMTPAERQATGELLTRISRNRTVVIVEHDMDFMRQFADSVTVLN
HHHCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHEECC
QGRILAEGSVEDIQNNEEVVRIYLGGGEDR
CCEEEECCCHHHHCCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043 [H]