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The map label for this gene is appC [H]

Identifier: 213690977

GI number: 213690977

Start: 62171

End: 63118

Strand: Direct

Name: appC [H]

Synonym: Blon_0055

Alternate gene names: 213690977

Gene position: 62171-63118 (Clockwise)

Preceding gene: 213690976

Following gene: 213690978

Centisome position: 2.19

GC content: 55.8

Gene sequence:

>948_bases
ATGGAACTACGTCGCAGTGAATCACGATCACGGTCGCAGCGATCAGCCAATGGGGGAAAGATGCGGAATTCTGGCGTTCG
ACCGTTATGGTATCGCAATCTTGTCCGGTTGGCGCACACACGTGCCGCGGCCGTCAGCATCGCCACGCTGGTTCTCGTGC
TGTTGCTCAGTGTTCTGGGGCCTTTGTTCAGTCCATACGGGCAAAACCAGTTGGATGTTCCCAATGCCGAACAGGGCCCT
ACTCTGGACCATCTGCTTGGCACGGATGATTACGGGCGAGATATCCTTACGCGATTGATGTATGCCGGTCGTATTTCCTT
GACCATCGGATTGGCGTCCACGGTCCTTTCCGTGGTGCTTGGCGCCACGATCGGCATTGCGTCCGGTTATTTTGGCGGAT
GGGTCGATGCCGTTATCATGCGTCTGGCGGATTTGCTGATGTCGATTCCAAGTCTGCCTTTGTTGATCATCATGGCCGCA
TTGCTCTCGGAGTTCAAGGTTCCCGCGAGTTCCCGCATCTATGTGGTGATGGTCATGTTGTCGATTATCGGCTGGCCGGG
TATGTCGCGCATGATCCGCGGTGAAGTGCTTTCATTAAGGGAACGTTTGTATATGAAAGCCACCGAGGCGTTGGGCCTGA
GCACAAGGTCGAGGCTGCTTCATCATCTGCTGCCCAATGTGCTGCCGCTGTTGATTGTGCAGACCACGTTAAGCGTCGCC
GGCGGCATTCTCATGGAATCCACGTTGAGCTTCCTGGGGCTTGGAGTCGTGCCGCCGAATGCGTCGTGGGGAAATATGAT
GGCGGCGGCTTCCAACCTCATGGACTTTCAGAAACGTCCATGGCTTTGGATTCCGCCGGGGGTCGCCGTATTCGTTACGG
TGGTGGCCATCAATGTCTTGGGTGATCGGCTACGCGACATCTACGATCCGAAGAATGAAAGGGCGTGA

Upstream 100 bases:

>100_bases
CTGCTGTCGTTTTTAACGATTCTGGCCAATTTCCTGGCCGACATCATGTATGCCGCTGCGGATCCACGTGTCCGGTTGGC
GCAGAAAGTTCAGGGTTGAC

Downstream 100 bases:

>100_bases
GGCATGGTTATTGCTTACGATACGGGAAATGGTTCGGATACGCATGAGCCGTTGCTGCGCGTGCGTGATCTGTGCGTCGA
ATTTCCTCTGGATGGAGGAG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MELRRSESRSRSQRSANGGKMRNSGVRPLWYRNLVRLAHTRAAAVSIATLVLVLLLSVLGPLFSPYGQNQLDVPNAEQGP
TLDHLLGTDDYGRDILTRLMYAGRISLTIGLASTVLSVVLGATIGIASGYFGGWVDAVIMRLADLLMSIPSLPLLIIMAA
LLSEFKVPASSRIYVVMVMLSIIGWPGMSRMIRGEVLSLRERLYMKATEALGLSTRSRLLHHLLPNVLPLLIVQTTLSVA
GGILMESTLSFLGLGVVPPNASWGNMMAAASNLMDFQKRPWLWIPPGVAVFVTVVAINVLGDRLRDIYDPKNERA

Sequences:

>Translated_315_residues
MELRRSESRSRSQRSANGGKMRNSGVRPLWYRNLVRLAHTRAAAVSIATLVLVLLLSVLGPLFSPYGQNQLDVPNAEQGP
TLDHLLGTDDYGRDILTRLMYAGRISLTIGLASTVLSVVLGATIGIASGYFGGWVDAVIMRLADLLMSIPSLPLLIIMAA
LLSEFKVPASSRIYVVMVMLSIIGWPGMSRMIRGEVLSLRERLYMKATEALGLSTRSRLLHHLLPNVLPLLIVQTTLSVA
GGILMESTLSFLGLGVVPPNASWGNMMAAASNLMDFQKRPWLWIPPGVAVFVTVVAINVLGDRLRDIYDPKNERA
>Mature_315_residues
MELRRSESRSRSQRSANGGKMRNSGVRPLWYRNLVRLAHTRAAAVSIATLVLVLLLSVLGPLFSPYGQNQLDVPNAEQGP
TLDHLLGTDDYGRDILTRLMYAGRISLTIGLASTVLSVVLGATIGIASGYFGGWVDAVIMRLADLLMSIPSLPLLIIMAA
LLSEFKVPASSRIYVVMVMLSIIGWPGMSRMIRGEVLSLRERLYMKATEALGLSTRSRLLHHLLPNVLPLLIVQTTLSVA
GGILMESTLSFLGLGVVPPNASWGNMMAAASNLMDFQKRPWLWIPPGVAVFVTVVAINVLGDRLRDIYDPKNERA

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=287, Percent_Identity=32.7526132404181, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787498, Length=307, Percent_Identity=35.8306188925081, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1787760, Length=311, Percent_Identity=33.1189710610932, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789889, Length=247, Percent_Identity=36.8421052631579, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789964, Length=266, Percent_Identity=36.0902255639098, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1788505, Length=233, Percent_Identity=29.6137339055794, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787549, Length=257, Percent_Identity=31.9066147859922, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34371; Mature: 34371

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELRRSESRSRSQRSANGGKMRNSGVRPLWYRNLVRLAHTRAAAVSIATLVLVLLLSVLG
CCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLFSPYGQNQLDVPNAEQGPTLDHLLGTDDYGRDILTRLMYAGRISLTIGLASTVLSVVL
HHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
GATIGIASGYFGGWVDAVIMRLADLLMSIPSLPLLIIMAALLSEFKVPASSRIYVVMVML
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SIIGWPGMSRMIRGEVLSLRERLYMKATEALGLSTRSRLLHHLLPNVLPLLIVQTTLSVA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGILMESTLSFLGLGVVPPNASWGNMMAAASNLMDFQKRPWLWIPPGVAVFVTVVAINVL
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHH
GDRLRDIYDPKNERA
HHHHHHHCCCCCCCC
>Mature Secondary Structure
MELRRSESRSRSQRSANGGKMRNSGVRPLWYRNLVRLAHTRAAAVSIATLVLVLLLSVLG
CCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLFSPYGQNQLDVPNAEQGPTLDHLLGTDDYGRDILTRLMYAGRISLTIGLASTVLSVVL
HHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
GATIGIASGYFGGWVDAVIMRLADLLMSIPSLPLLIIMAALLSEFKVPASSRIYVVMVML
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
SIIGWPGMSRMIRGEVLSLRERLYMKATEALGLSTRSRLLHHLLPNVLPLLIVQTTLSVA
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGILMESTLSFLGLGVVPPNASWGNMMAAASNLMDFQKRPWLWIPPGVAVFVTVVAINVL
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHH
GDRLRDIYDPKNERA
HHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]