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The map label for this gene is ahpC [H]

Identifier: 213690959

GI number: 213690959

Start: 36423

End: 36986

Strand: Direct

Name: ahpC [H]

Synonym: Blon_0035

Alternate gene names: 213690959

Gene position: 36423-36986 (Clockwise)

Preceding gene: 213690957

Following gene: 213690960

Centisome position: 1.29

GC content: 61.52

Gene sequence:

>564_bases
ATGACTCTTCTGCAGCATGAACTGACCGATTTCAAGGTGAACGCATTCCAGAACAACGAGTTCCACGAAGTGACCAAGGA
CGATGTGCTCGGCCACTGGTCCCTGTTCTTCTTCTACCCGGCCGACTTCACCTTCGTGTGCCCCACCGAGCTTGAAGACC
TGGCCAAGAACTACGCCAAGTTCAAGGAAATCGGCTGCGAGATCTACTCCGTCTCCTGCGACACCCACTTCGTGCACAAG
GCTTGGCACGACGCCAACGAGAAGATCGCCAAGATCGAGTACCCGATGCTTGCCGACCCGACCGCCCTGCTGGCCAAGGA
TCTCGACACCTACAACGAGGCCGATGGCATGGCCGAGCGCGGCGACTTCATCGTGAGCCCCGAGGGCAAGGTCGTGGCCT
ACGAGGTCATCTCCTCCAACGTGGGCCGCAACGCCGAGGAGCTGCTGCGCCGCGTGCAGGCCTCCCAGTTCGTCTACGAG
CACGGCGACCAGGTCTGCCCCGCCAACTGGACCCCTGGCGAGGAAACCATCGAGCCCAGCCTCGACCTCGTCGGCCAGCT
GTGA

Upstream 100 bases:

>100_bases
GATAAGGCTCATACGTTACACCCGCGCGAGCCGTGGCTCACCACATTACGATAGGTGGTGGTAAACGCTTGAAGATTAAC
AATTCCCGAAAGGACCGATG

Downstream 100 bases:

>100_bases
TCGACACTGAATAGGCGGTAACCTTGGCTCCCCTCTCTGAGGGGAGCTGTCGCTGAAAGCGACTGGGGGGAGTGCTCGCG
AGAGCTAGCCTGATCCGATA

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MTLLQHELTDFKVNAFQNNEFHEVTKDDVLGHWSLFFFYPADFTFVCPTELEDLAKNYAKFKEIGCEIYSVSCDTHFVHK
AWHDANEKIAKIEYPMLADPTALLAKDLDTYNEADGMAERGDFIVSPEGKVVAYEVISSNVGRNAEELLRRVQASQFVYE
HGDQVCPANWTPGEETIEPSLDLVGQL

Sequences:

>Translated_187_residues
MTLLQHELTDFKVNAFQNNEFHEVTKDDVLGHWSLFFFYPADFTFVCPTELEDLAKNYAKFKEIGCEIYSVSCDTHFVHK
AWHDANEKIAKIEYPMLADPTALLAKDLDTYNEADGMAERGDFIVSPEGKVVAYEVISSNVGRNAEELLRRVQASQFVYE
HGDQVCPANWTPGEETIEPSLDLVGQL
>Mature_186_residues
TLLQHELTDFKVNAFQNNEFHEVTKDDVLGHWSLFFFYPADFTFVCPTELEDLAKNYAKFKEIGCEIYSVSCDTHFVHKA
WHDANEKIAKIEYPMLADPTALLAKDLDTYNEADGMAERGDFIVSPEGKVVAYEVISSNVGRNAEELLRRVQASQFVYEH
GDQVCPANWTPGEETIEPSLDLVGQL

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32189392, Length=176, Percent_Identity=41.4772727272727, Blast_Score=144, Evalue=4e-35,
Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=42.1965317919075, Blast_Score=144, Evalue=4e-35,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=42.1965317919075, Blast_Score=144, Evalue=4e-35,
Organism=Homo sapiens, GI4505591, Length=182, Percent_Identity=36.8131868131868, Blast_Score=137, Evalue=5e-33,
Organism=Homo sapiens, GI32455266, Length=182, Percent_Identity=36.8131868131868, Blast_Score=137, Evalue=5e-33,
Organism=Homo sapiens, GI32455264, Length=182, Percent_Identity=36.8131868131868, Blast_Score=137, Evalue=5e-33,
Organism=Homo sapiens, GI5453549, Length=177, Percent_Identity=39.5480225988701, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI33188454, Length=79, Percent_Identity=43.0379746835443, Blast_Score=80, Evalue=9e-16,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=50.8021390374332, Blast_Score=223, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI193204376, Length=174, Percent_Identity=39.6551724137931, Blast_Score=133, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=39.6551724137931, Blast_Score=133, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17554494, Length=180, Percent_Identity=35, Blast_Score=126, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI25153706, Length=185, Percent_Identity=28.1081081081081, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=35.7142857142857, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=32.5966850828729, Blast_Score=109, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6319407, Length=164, Percent_Identity=31.0975609756098, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17738015, Length=184, Percent_Identity=39.1304347826087, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI21357347, Length=172, Percent_Identity=38.953488372093, Blast_Score=140, Evalue=5e-34,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=37.7777777777778, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=37.7777777777778, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24656348, Length=173, Percent_Identity=39.3063583815029, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17864676, Length=173, Percent_Identity=39.3063583815029, Blast_Score=130, Evalue=4e-31,
Organism=Drosophila melanogaster, GI17975518, Length=156, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24652436, Length=161, Percent_Identity=34.1614906832298, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24652434, Length=156, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24581278, Length=151, Percent_Identity=30.4635761589404, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21243; Mature: 21112

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLLQHELTDFKVNAFQNNEFHEVTKDDVLGHWSLFFFYPADFTFVCPTELEDLAKNYAK
CCCHHHHCCCEEEEEECCCCCHHHCHHHHCCCEEEEEEECCCEEEECCHHHHHHHHHHHH
FKEIGCEIYSVSCDTHFVHKAWHDANEKIAKIEYPMLADPTALLAKDLDTYNEADGMAER
HHHHCCEEEEEECCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
GDFIVSPEGKVVAYEVISSNVGRNAEELLRRVQASQFVYEHGDQVCPANWTPGEETIEPS
CCEEECCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
LDLVGQL
HHHHCCC
>Mature Secondary Structure 
TLLQHELTDFKVNAFQNNEFHEVTKDDVLGHWSLFFFYPADFTFVCPTELEDLAKNYAK
CCHHHHCCCEEEEEECCCCCHHHCHHHHCCCEEEEEEECCCEEEECCHHHHHHHHHHHH
FKEIGCEIYSVSCDTHFVHKAWHDANEKIAKIEYPMLADPTALLAKDLDTYNEADGMAER
HHHHCCEEEEEECCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
GDFIVSPEGKVVAYEVISSNVGRNAEELLRRVQASQFVYEHGDQVCPANWTPGEETIEPS
CCEEECCCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
LDLVGQL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]