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The map label for this gene is pncB [H]

Identifier: 213159122

GI number: 213159122

Start: 3954511

End: 3955575

Strand: Reverse

Name: pncB [H]

Synonym: AB57_3832

Alternate gene names: 213159122

Gene position: 3955575-3954511 (Counterclockwise)

Preceding gene: 213159124

Following gene: 213159121

Centisome position: 97.66

GC content: 38.03

Gene sequence:

>1065_bases
TTGGATGACTTAAACGAGCAACTCGACCATTTATGTAATCTCAAATATAAAGAAGACGAACTACAATATTTAAGAAAATT
ACGATTTATTAAAAGCGACTTTGTCGATTATTTAGAATTATTTCAACTCAAACGCCGTTTTATTCATGCGAGTATAGATG
AAGAAGGTCGATTAGACATCCGTATTGAAGGGCCAATGGTTCAAGCCATGATGTTTGAGATTTTTGTTTTAGCCATTGTA
AATGAATTATATTTTAGCCGGATTAAAACAGATGAAGTCTGGGCTGAAGGCGAACGCCGTTTACAAGCAAAACTTGAATT
AATTCAGCAATACGAAAAAGCTCAACAACCGAATGATCCACCATTTTTAGTTTCTGATTTTGGTACCCGCCGTCGTTATA
GTTTTGAATGGCAAAAACATGTAGTTGCTGCATTTCATAACACTGTGCCAAATGTGTTCCGTGGTACAAGTAACGTCTTG
CTTGCCAAAGAGTTAAATATTACGCCAATTGGAACCATGGCCCATGAATTCTTACAGGCTTTTCAGGCGCTTGATGTTCG
CTTACGTGACTTTCAAAAAGCTGCTTTAGAAACGTGGGTTCAAGAATATCGCGGAGACTTAGGAATTGCTTTAACTGACG
TAGTTGGTATGGACGCTTTCCTCAGAGATTTTGATTTGTATTTTGCCAAATTATTTGATGGCTTACGTCATGACAGTGGT
GATCCGTACGAGTGGGGTGATAAAGCATATGCACACTATCGTAAATTAAAAATTGATACCAAAACCAAAATGTTGACCTT
TAGTGATGGCCTTAATTTGCCAAAGGCTTGGGAACTACATCAATATTTCAAAGACCGTTTTCAGGTGAGTTTCGGTATTG
GTACTAATTTGACCAATGACATGGGCCAAACACCGCTCAATATTGTATTGAAACTGGTTGAGTGTAATGGCCAGTCTGTT
GCTAAAATTTCGGACAGCCCTGGTAAAACCATGACTGATAACGATACATTCTTGGCCTATTTACGTCAGGTTTTCCAAAT
TGAAGAGCTGGATGAAGCAATTTAA

Upstream 100 bases:

>100_bases
GATGCTACAAGTGGTTCTGCATAAATTCCCGCAAACGCATAGCGTCTATCACTTTCGTTGCAGAAATTTAGAAGATACGG
TCTATCCATTAGTGGATATT

Downstream 100 bases:

>100_bases
TTACAATAGAGCTTAAGCGCTTGGCAGCCACTTAAGACTTGAGAATTTTAATATCTGATTTTCTGCTAAACACTAGCAGA
AAATCAGAGTTTGATAGATA

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MDDLNEQLDHLCNLKYKEDELQYLRKLRFIKSDFVDYLELFQLKRRFIHASIDEEGRLDIRIEGPMVQAMMFEIFVLAIV
NELYFSRIKTDEVWAEGERRLQAKLELIQQYEKAQQPNDPPFLVSDFGTRRRYSFEWQKHVVAAFHNTVPNVFRGTSNVL
LAKELNITPIGTMAHEFLQAFQALDVRLRDFQKAALETWVQEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSG
DPYEWGDKAYAHYRKLKIDTKTKMLTFSDGLNLPKAWELHQYFKDRFQVSFGIGTNLTNDMGQTPLNIVLKLVECNGQSV
AKISDSPGKTMTDNDTFLAYLRQVFQIEELDEAI

Sequences:

>Translated_354_residues
MDDLNEQLDHLCNLKYKEDELQYLRKLRFIKSDFVDYLELFQLKRRFIHASIDEEGRLDIRIEGPMVQAMMFEIFVLAIV
NELYFSRIKTDEVWAEGERRLQAKLELIQQYEKAQQPNDPPFLVSDFGTRRRYSFEWQKHVVAAFHNTVPNVFRGTSNVL
LAKELNITPIGTMAHEFLQAFQALDVRLRDFQKAALETWVQEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSG
DPYEWGDKAYAHYRKLKIDTKTKMLTFSDGLNLPKAWELHQYFKDRFQVSFGIGTNLTNDMGQTPLNIVLKLVECNGQSV
AKISDSPGKTMTDNDTFLAYLRQVFQIEELDEAI
>Mature_354_residues
MDDLNEQLDHLCNLKYKEDELQYLRKLRFIKSDFVDYLELFQLKRRFIHASIDEEGRLDIRIEGPMVQAMMFEIFVLAIV
NELYFSRIKTDEVWAEGERRLQAKLELIQQYEKAQQPNDPPFLVSDFGTRRRYSFEWQKHVVAAFHNTVPNVFRGTSNVL
LAKELNITPIGTMAHEFLQAFQALDVRLRDFQKAALETWVQEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSG
DPYEWGDKAYAHYRKLKIDTKTKMLTFSDGLNLPKAWELHQYFKDRFQVSFGIGTNLTNDMGQTPLNIVLKLVECNGQSV
AKISDSPGKTMTDNDTFLAYLRQVFQIEELDEAI

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=353, Percent_Identity=44.7592067988669, Blast_Score=292, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6324783, Length=361, Percent_Identity=32.9639889196676, Blast_Score=176, Evalue=4e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 41344; Mature: 41344

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDLNEQLDHLCNLKYKEDELQYLRKLRFIKSDFVDYLELFQLKRRFIHASIDEEGRLDI
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
RIEGPMVQAMMFEIFVLAIVNELYFSRIKTDEVWAEGERRLQAKLELIQQYEKAQQPNDP
EECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PFLVSDFGTRRRYSFEWQKHVVAAFHNTVPNVFRGTSNVLLAKELNITPIGTMAHEFLQA
CEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHH
FQALDVRLRDFQKAALETWVQEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPYEWGDKAYAHYRKLKIDTKTKMLTFSDGLNLPKAWELHQYFKDRFQVSFGIGTNLTND
CCCCCCCHHHHHHHHEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCC
MGQTPLNIVLKLVECNGQSVAKISDSPGKTMTDNDTFLAYLRQVFQIEELDEAI
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDDLNEQLDHLCNLKYKEDELQYLRKLRFIKSDFVDYLELFQLKRRFIHASIDEEGRLDI
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
RIEGPMVQAMMFEIFVLAIVNELYFSRIKTDEVWAEGERRLQAKLELIQQYEKAQQPNDP
EECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PFLVSDFGTRRRYSFEWQKHVVAAFHNTVPNVFRGTSNVLLAKELNITPIGTMAHEFLQA
CEEEECCCCCCCCCHHHHHHHHHHHHHHCHHHHCCCCCEEEEECCCCCCHHHHHHHHHHH
FQALDVRLRDFQKAALETWVQEYRGDLGIALTDVVGMDAFLRDFDLYFAKLFDGLRHDSG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DPYEWGDKAYAHYRKLKIDTKTKMLTFSDGLNLPKAWELHQYFKDRFQVSFGIGTNLTND
CCCCCCCHHHHHHHHEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCC
MGQTPLNIVLKLVECNGQSVAKISDSPGKTMTDNDTFLAYLRQVFQIEELDEAI
CCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA