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The map label for this gene is dsbB [H]

Identifier: 213159108

GI number: 213159108

Start: 3939669

End: 3940184

Strand: Reverse

Name: dsbB [H]

Synonym: AB57_3818

Alternate gene names: 213159108

Gene position: 3940184-3939669 (Counterclockwise)

Preceding gene: 213159109

Following gene: 213159107

Centisome position: 97.28

GC content: 42.25

Gene sequence:

>516_bases
ATGCGATTAAGTTACCGTTTGGTGAGTGGACTGCTTGTTCTGGCAAGCATTGTCGGCATGTCTTTTGCGTTGTATTTGGA
ACATGTAAAAGGGTTGGAGCCATGTCCGCTCTGTATTTTTCAACGTGTTGGCTTAATGGCAATGGGTTTTGTGGCTCTTA
TTGCGTTTTTGCATAACCCGGTTTCCAATGCGATTAAACGCTTTTATGCATTTTTGGCAGGTGTTGCAATTTTATGGTCA
GTAGGGGTGGCGGGCCGACATGTTTGGCTACAGCATTTACCACCAGATCAAGTGCCAAGCTGTGGTCCGGGTTTAAATTA
CCTCATTGATGCTTTACCAATGAAAACCGTTTTACAAGAAGTACTTTCTGGCTCAGGTGAGTGTGCGGCAATTGACTGGA
CTTTTTTAGGTCAGTCTTTACCAGTTTGGTCATTGGTCTATTTCCTTTTACTATTACTGGTTTGTTTATGGCAGTTATTC
CGTTTTTATCCAGTGTTTAAGACGGCTAAAAAGTAA

Upstream 100 bases:

>100_bases
TGGCTGTGCAATCTTTACAGCAGCAAGAACAACTTGAGCAAGATAGTCAGATCAGTTTTGATCAATATCTTGAACAATAT
AGATAAAAACGAGGTTTTAC

Downstream 100 bases:

>100_bases
GTTTAAAGTAATTAAAAAGGCTCAACTTAAGTTGGGCTTTTTTTATAACTTTCGAATAAGTGAAAATATAAAAAAATTGA
TAGAAATAACGCATAATTTT

Product: disulfide bond formation protein

Products: glutathione disulfide; Protein dithiol

Alternate protein names: Disulfide oxidoreductase [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MRLSYRLVSGLLVLASIVGMSFALYLEHVKGLEPCPLCIFQRVGLMAMGFVALIAFLHNPVSNAIKRFYAFLAGVAILWS
VGVAGRHVWLQHLPPDQVPSCGPGLNYLIDALPMKTVLQEVLSGSGECAAIDWTFLGQSLPVWSLVYFLLLLLVCLWQLF
RFYPVFKTAKK

Sequences:

>Translated_171_residues
MRLSYRLVSGLLVLASIVGMSFALYLEHVKGLEPCPLCIFQRVGLMAMGFVALIAFLHNPVSNAIKRFYAFLAGVAILWS
VGVAGRHVWLQHLPPDQVPSCGPGLNYLIDALPMKTVLQEVLSGSGECAAIDWTFLGQSLPVWSLVYFLLLLLVCLWQLF
RFYPVFKTAKK
>Mature_171_residues
MRLSYRLVSGLLVLASIVGMSFALYLEHVKGLEPCPLCIFQRVGLMAMGFVALIAFLHNPVSNAIKRFYAFLAGVAILWS
VGVAGRHVWLQHLPPDQVPSCGPGLNYLIDALPMKTVLQEVLSGSGECAAIDWTFLGQSLPVWSLVYFLLLLLVCLWQLF
RFYPVFKTAKK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein [H]

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003752
- InterPro:   IPR022920 [H]

Pfam domain/function: PF02600 DsbB [H]

EC number: 1.8.4.2

Molecular weight: Translated: 19000; Mature: 19000

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSYRLVSGLLVLASIVGMSFALYLEHVKGLEPCPLCIFQRVGLMAMGFVALIAFLHNP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
VSNAIKRFYAFLAGVAILWSVGVAGRHVWLQHLPPDQVPSCGPGLNYLIDALPMKTVLQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VLSGSGECAAIDWTFLGQSLPVWSLVYFLLLLLVCLWQLFRFYPVFKTAKK
HHCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLSYRLVSGLLVLASIVGMSFALYLEHVKGLEPCPLCIFQRVGLMAMGFVALIAFLHNP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
VSNAIKRFYAFLAGVAILWSVGVAGRHVWLQHLPPDQVPSCGPGLNYLIDALPMKTVLQE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VLSGSGECAAIDWTFLGQSLPVWSLVYFLLLLLVCLWQLFRFYPVFKTAKK
HHCCCCCEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; Protein disulfide

Specific reaction: 2 glutathione + protein-disulfide = glutathione disulfide + protein-dithiol

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA