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The map label for this gene is yhcK [H]

Identifier: 213159087

GI number: 213159087

Start: 3915540

End: 3916733

Strand: Direct

Name: yhcK [H]

Synonym: AB57_3797

Alternate gene names: 213159087

Gene position: 3915540-3916733 (Clockwise)

Preceding gene: 213159085

Following gene: 213159091

Centisome position: 96.67

GC content: 36.6

Gene sequence:

>1194_bases
ATGAAAATTCGTTTAATCACTCGTCCTATAAATAAAATAAAACAGGTGATTCTCGATTTCATCCATCACAATCACATTAT
TAACTGGACCCCATTACAAAAAAGCGCCCTAATGCTTACCCTCGCCTGCGCAATGAATTTCAGTTGGATTTTATGGAAAG
GCTATATTTTAATTACTCCTAGTATTTGGCAATGGGCAAACCTATCTTTAGTTGAATCACAAATCTGGCTGAATTTACTG
ACCTTATTTTTATTAGCTGTACTCATTATTCCTTGTTATCGCTACAAAGACCAAGCTTGGGCGCAAAAAATTGTGCCTTT
AATTAGTGTACAAGCCTTTATGCTGATGTTGTGCCACGATGGATATTTAATTGGTAGTATCAGCCCTGCCACAATGGTGG
GTTACGTAGGCACTATTGGCGTAGGTTTGGTTTTATTTGAAAGAAAAATTGTTTATAGCGCTTTTATACCTGCAACTATT
ATTCTAGCGGTATGTACATATTTAAGTATGACGGGGGTTATCTCATATGCGCCCCTATTTAATTTTAAAACGATGCGTCA
TGCCCAAACCAATCCATTTTGGCTAGGAAGTATGCTGTTTTTTATTATGCCTATTTTAGTGGCGTGTTTTATTTTATTTG
AAATATTGCTGACCCAATGGCGTCAACGAGAAACCTATATTCAACGTTTAAGCCAAATCGACCCGTTAACTAATGTCTTA
AATAGACGAAGCTTAAACACTCATCTTGAAGCACTTCATGAGCAACAATTTGATTATGCCGTGATACTTCTTGATATCGA
TCATTTTAAAAAAATTAATGATATATACGGACATCACCAAGGTGATCAGGTTTTGATTGAAATTGCTCGGTGTCTTTCTG
AAAACTTACGTAATGAAGATATTATTGGACGTTTTGGTGGAGAAGAATTTATTTTATTACTTCCTCATACCGATATTATT
CAAGCAGAAAAAATTGCTGAACGTTGCCGGCAAGCTTTACAAGAATTGACTATCTTCAATAATCAAAATATCCAAATTCA
TGTAAGTGCCAGCTTTGGCATCAGCAGTTCGGCTTTTGCAAATGACCCCTATCTTGTGATTAGACAAGCCGATCAAGCGC
TCTATGCGGTAAAGGCCTCTGGGCGTAATCAAGTACGCACTTTTCATCAACTACCTCAGATCAAATCAATTTGA

Upstream 100 bases:

>100_bases
TTATGAATCATGGTATGTTTAGGTTATGAATCCTTCAAACTCTCCCTCTTTAGGATGATCTGACGAAGAGACATCTCTAT
TTAGGAGTTCCTTTATTATT

Downstream 100 bases:

>100_bases
ATCTTTAGCTTTTGATAAGCTTGCCAGCTGTTGTAAAAGCTCTTGCTGACTAAAGGCGCCTGTTAAACGTAAAGAACGAA
TTTCTTGCTGTTGCTTGTTT

Product: GGDEF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKIRLITRPINKIKQVILDFIHHNHIINWTPLQKSALMLTLACAMNFSWILWKGYILITPSIWQWANLSLVESQIWLNLL
TLFLLAVLIIPCYRYKDQAWAQKIVPLISVQAFMLMLCHDGYLIGSISPATMVGYVGTIGVGLVLFERKIVYSAFIPATI
ILAVCTYLSMTGVISYAPLFNFKTMRHAQTNPFWLGSMLFFIMPILVACFILFEILLTQWRQRETYIQRLSQIDPLTNVL
NRRSLNTHLEALHEQQFDYAVILLDIDHFKKINDIYGHHQGDQVLIEIARCLSENLRNEDIIGRFGGEEFILLLPHTDII
QAEKIAERCRQALQELTIFNNQNIQIHVSASFGISSSAFANDPYLVIRQADQALYAVKASGRNQVRTFHQLPQIKSI

Sequences:

>Translated_397_residues
MKIRLITRPINKIKQVILDFIHHNHIINWTPLQKSALMLTLACAMNFSWILWKGYILITPSIWQWANLSLVESQIWLNLL
TLFLLAVLIIPCYRYKDQAWAQKIVPLISVQAFMLMLCHDGYLIGSISPATMVGYVGTIGVGLVLFERKIVYSAFIPATI
ILAVCTYLSMTGVISYAPLFNFKTMRHAQTNPFWLGSMLFFIMPILVACFILFEILLTQWRQRETYIQRLSQIDPLTNVL
NRRSLNTHLEALHEQQFDYAVILLDIDHFKKINDIYGHHQGDQVLIEIARCLSENLRNEDIIGRFGGEEFILLLPHTDII
QAEKIAERCRQALQELTIFNNQNIQIHVSASFGISSSAFANDPYLVIRQADQALYAVKASGRNQVRTFHQLPQIKSI
>Mature_397_residues
MKIRLITRPINKIKQVILDFIHHNHIINWTPLQKSALMLTLACAMNFSWILWKGYILITPSIWQWANLSLVESQIWLNLL
TLFLLAVLIIPCYRYKDQAWAQKIVPLISVQAFMLMLCHDGYLIGSISPATMVGYVGTIGVGLVLFERKIVYSAFIPATI
ILAVCTYLSMTGVISYAPLFNFKTMRHAQTNPFWLGSMLFFIMPILVACFILFEILLTQWRQRETYIQRLSQIDPLTNVL
NRRSLNTHLEALHEQQFDYAVILLDIDHFKKINDIYGHHQGDQVLIEIARCLSENLRNEDIIGRFGGEEFILLLPHTDII
QAEKIAERCRQALQELTIFNNQNIQIHVSASFGISSSAFANDPYLVIRQADQALYAVKASGRNQVRTFHQLPQIKSI

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1787262, Length=162, Percent_Identity=38.2716049382716, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI87082007, Length=158, Percent_Identity=40.5063291139241, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI87081881, Length=173, Percent_Identity=34.1040462427746, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788085, Length=189, Percent_Identity=33.8624338624339, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786584, Length=197, Percent_Identity=29.9492385786802, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787802, Length=222, Percent_Identity=30.1801801801802, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI145693134, Length=157, Percent_Identity=34.3949044585987, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787541, Length=175, Percent_Identity=31.4285714285714, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788381, Length=165, Percent_Identity=34.5454545454545, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=34.5679012345679, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787056, Length=154, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081977, Length=178, Percent_Identity=28.6516853932584, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87081921, Length=169, Percent_Identity=26.6272189349112, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081974, Length=186, Percent_Identity=26.3440860215054, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 45643; Mature: 45643

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRLITRPINKIKQVILDFIHHNHIINWTPLQKSALMLTLACAMNFSWILWKGYILITP
CEEEEEHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCEEEEECEEEECC
SIWQWANLSLVESQIWLNLLTLFLLAVLIIPCYRYKDQAWAQKIVPLISVQAFMLMLCHD
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
GYLIGSISPATMVGYVGTIGVGLVLFERKIVYSAFIPATIILAVCTYLSMTGVISYAPLF
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFKTMRHAQTNPFWLGSMLFFIMPILVACFILFEILLTQWRQRETYIQRLSQIDPLTNVL
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
NRRSLNTHLEALHEQQFDYAVILLDIDHFKKINDIYGHHQGDQVLIEIARCLSENLRNED
HHCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
IIGRFGGEEFILLLPHTDIIQAEKIAERCRQALQELTIFNNQNIQIHVSASFGISSSAFA
CEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCC
NDPYLVIRQADQALYAVKASGRNQVRTFHQLPQIKSI
CCCEEEEEECCHHEEEEECCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKIRLITRPINKIKQVILDFIHHNHIINWTPLQKSALMLTLACAMNFSWILWKGYILITP
CEEEEEHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCEEEEECEEEECC
SIWQWANLSLVESQIWLNLLTLFLLAVLIIPCYRYKDQAWAQKIVPLISVQAFMLMLCHD
CHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
GYLIGSISPATMVGYVGTIGVGLVLFERKIVYSAFIPATIILAVCTYLSMTGVISYAPLF
CEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFKTMRHAQTNPFWLGSMLFFIMPILVACFILFEILLTQWRQRETYIQRLSQIDPLTNVL
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
NRRSLNTHLEALHEQQFDYAVILLDIDHFKKINDIYGHHQGDQVLIEIARCLSENLRNED
HHCCHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
IIGRFGGEEFILLLPHTDIIQAEKIAERCRQALQELTIFNNQNIQIHVSASFGISSSAFA
CEEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCC
NDPYLVIRQADQALYAVKASGRNQVRTFHQLPQIKSI
CCCEEEEEECCHHEEEEECCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]