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The map label for this gene is lpxC [H]

Identifier: 213159070

GI number: 213159070

Start: 3899428

End: 3899751

Strand: Reverse

Name: lpxC [H]

Synonym: AB57_3780

Alternate gene names: 213159070

Gene position: 3899751-3899428 (Counterclockwise)

Preceding gene: 213159071

Following gene: 213159068

Centisome position: 96.28

GC content: 35.19

Gene sequence:

>324_bases
ATGAAAGACTTGGATTACCTTAAAGCAAATAATTTAGCTTTAGGAGCAAGTCTAGATAATGCAATTGGCGTAGATGATAC
AGGTGTTGTAAACGAAGAAGGTTTACGATTTGCCGATGAGTTTGTTCGTCACAAAATTTTAGATGCAGTTGGTGATTTGT
ATTTACTTGGTCATCAAATTATTGCCAAGTTTGATGGCTATAAATCAGGACATGCCTTAAATAATCAGCTATTACGCAAT
GTTCAAAGCGATCCGAGTAATTATGAAATTGTAACATTTGATGACGAGAAAGACTGTCCAATTCCATACGTGAGTGTGAC
ATAA

Upstream 100 bases:

>100_bases
TGATCATCCTGCATTTGCCAAAGAATATCAGTCTGCAACTATCGATTTTTCTACTGAAACGTTTGTGTATGAGGTCAGTG
AGGCACGAACTTTTGGTTTT

Downstream 100 bases:

>100_bases
GTCATTGTCTTTATTTGGCTATGTTATAATGTAACATTAGTAAGTGTGATTTTTATCACATATTAAGAACGATTCTAATT
AAGAAATAGAAAGCTCATCA

Product: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase

Products: NA

Alternate protein names: UDP-3-O-acyl-GlcNAc deacetylase [H]

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MKDLDYLKANNLALGASLDNAIGVDDTGVVNEEGLRFADEFVRHKILDAVGDLYLLGHQIIAKFDGYKSGHALNNQLLRN
VQSDPSNYEIVTFDDEKDCPIPYVSVT

Sequences:

>Translated_107_residues
MKDLDYLKANNLALGASLDNAIGVDDTGVVNEEGLRFADEFVRHKILDAVGDLYLLGHQIIAKFDGYKSGHALNNQLLRN
VQSDPSNYEIVTFDDEKDCPIPYVSVT
>Mature_107_residues
MKDLDYLKANNLALGASLDNAIGVDDTGVVNEEGLRFADEFVRHKILDAVGDLYLLGHQIIAKFDGYKSGHALNNQLLRN
VQSDPSNYEIVTFDDEKDCPIPYVSVT

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG0774

COG function: function code M; UDP-3-O-acyl-N-acetylglucosamine deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxC family [H]

Homologues:

Organism=Escherichia coli, GI1786285, Length=103, Percent_Identity=55.3398058252427, Blast_Score=125, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020568
- InterPro:   IPR004463
- InterPro:   IPR011334
- InterPro:   IPR015870 [H]

Pfam domain/function: PF03331 LpxC [H]

EC number: 3.5.1.-

Molecular weight: Translated: 11842; Mature: 11842

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLDYLKANNLALGASLDNAIGVDDTGVVNEEGLRFADEFVRHKILDAVGDLYLLGHQI
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAKFDGYKSGHALNNQLLRNVQSDPSNYEIVTFDDEKDCPIPYVSVT
HHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEECC
>Mature Secondary Structure
MKDLDYLKANNLALGASLDNAIGVDDTGVVNEEGLRFADEFVRHKILDAVGDLYLLGHQI
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IAKFDGYKSGHALNNQLLRNVQSDPSNYEIVTFDDEKDCPIPYVSVT
HHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on carbon-nitrogen bonds, other than peptide bonds; In linear amides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA