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The map label for this gene is yrkL [H]

Identifier: 213158999

GI number: 213158999

Start: 3819650

End: 3820207

Strand: Reverse

Name: yrkL [H]

Synonym: AB57_3706

Alternate gene names: 213158999

Gene position: 3820207-3819650 (Counterclockwise)

Preceding gene: 213159003

Following gene: 213158997

Centisome position: 94.31

GC content: 37.81

Gene sequence:

>558_bases
ATGAAAAAGACATTAGTGATCGTTGCGCATCCTCACATAGACCAGTCTGTAATTAATAAAAGATGGGTAGAGGAGTTAGA
AAAATATCCCGACCAATTTACCGTTCACCAGATTTATCAAGCCTACCCAGATGGCGTAATTGATGTTGCCAAAGAACAAG
CACTTGTAGAAGAACACGAAAATTTAGTTTTTCAATTTCCAGTGTATTGGTTTAACTGTCCGCCGCTTTTGAAACAATGG
CTTGATGAAGTTTTGGCATATGGTTGGGCTTACGGTTCAACAGGTGACAAGCTTAAAAATAAAAAATTTATGCTGGCGGT
GTCTGCGGGTGCTCAAGAAAAAGTTTATTCAGAGCAAGGTGAATATAAGCTTTCGTTAGAGCAGATTTTTAGTTCTTTTG
AACTTACTGCTTTATATATTGGGGCAGTCTATCAACCGCTTTATGCATTTTATGGTTTAGACACAAACCCTTCACCAGAT
GATGCTATTCCAACTCACCAAGAAATAGATAACAGTGCCGTTCAGTATGTTCAGAAATTATTAGCATTGTCTGAGTAA

Upstream 100 bases:

>100_bases
ATCTTTTAGTATAGTATATAACAAAAATTACCGTACTTATATTTAGGAAAGCACACTTCTATAATCGATTTATCTATTTT
TCGATAAGAGTGTTTTTATA

Downstream 100 bases:

>100_bases
TTTTTAAAAGAGAGACCTAAGCGTGATTGTTTAGGCGCTTTTACGATATTGAAGTAAGGTAAAACCAGTATGCTTTTTAA
AATAACGGCACATATAGGAG

Product: NAD(P)H oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MKKTLVIVAHPHIDQSVINKRWVEELEKYPDQFTVHQIYQAYPDGVIDVAKEQALVEEHENLVFQFPVYWFNCPPLLKQW
LDEVLAYGWAYGSTGDKLKNKKFMLAVSAGAQEKVYSEQGEYKLSLEQIFSSFELTALYIGAVYQPLYAFYGLDTNPSPD
DAIPTHQEIDNSAVQYVQKLLALSE

Sequences:

>Translated_185_residues
MKKTLVIVAHPHIDQSVINKRWVEELEKYPDQFTVHQIYQAYPDGVIDVAKEQALVEEHENLVFQFPVYWFNCPPLLKQW
LDEVLAYGWAYGSTGDKLKNKKFMLAVSAGAQEKVYSEQGEYKLSLEQIFSSFELTALYIGAVYQPLYAFYGLDTNPSPD
DAIPTHQEIDNSAVQYVQKLLALSE
>Mature_185_residues
MKKTLVIVAHPHIDQSVINKRWVEELEKYPDQFTVHQIYQAYPDGVIDVAKEQALVEEHENLVFQFPVYWFNCPPLLKQW
LDEVLAYGWAYGSTGDKLKNKKFMLAVSAGAQEKVYSEQGEYKLSLEQIFSSFELTALYIGAVYQPLYAFYGLDTNPSPD
DAIPTHQEIDNSAVQYVQKLLALSE

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family [H]

Homologues:

Organism=Escherichia coli, GI1789750, Length=135, Percent_Identity=38.5185185185185, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786231, Length=181, Percent_Identity=33.1491712707182, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 21227; Mature: 21227

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLVIVAHPHIDQSVINKRWVEELEKYPDQFTVHQIYQAYPDGVIDVAKEQALVEEHE
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
NLVFQFPVYWFNCPPLLKQWLDEVLAYGWAYGSTGDKLKNKKFMLAVSAGAQEKVYSEQG
CEEEEECCEEECCCHHHHHHHHHHHHHHCCCCCCCCHHCCCEEEEEECCCCHHHHHHCCC
EYKLSLEQIFSSFELTALYIGAVYQPLYAFYGLDTNPSPDDAIPTHQEIDNSAVQYVQKL
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LALSE
HHCCC
>Mature Secondary Structure
MKKTLVIVAHPHIDQSVINKRWVEELEKYPDQFTVHQIYQAYPDGVIDVAKEQALVEEHE
CCCEEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
NLVFQFPVYWFNCPPLLKQWLDEVLAYGWAYGSTGDKLKNKKFMLAVSAGAQEKVYSEQG
CEEEEECCEEECCCHHHHHHHHHHHHHHCCCCCCCCHHCCCEEEEEECCCCHHHHHHCCC
EYKLSLEQIFSSFELTALYIGAVYQPLYAFYGLDTNPSPDDAIPTHQEIDNSAVQYVQKL
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LALSE
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]