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The map label for this gene is aroB

Identifier: 213158941

GI number: 213158941

Start: 3751343

End: 3752425

Strand: Reverse

Name: aroB

Synonym: AB57_3642

Alternate gene names: 213158941

Gene position: 3752425-3751343 (Counterclockwise)

Preceding gene: 213158942

Following gene: 213158940

Centisome position: 92.64

GC content: 40.35

Gene sequence:

>1083_bases
ATGCAAACTTTACATGTTGAATTAGGCGAACGCCGTTATCCTATTTTCATTGGTAGCCAACTTGACCCGAAACAATTACT
AGAGCCTTATATTCATGGTCAACAGGTCATGATTGTGAGTAATGTTACGGTTGCGCCTTTATATTTAAGCCACTATCAGG
AAGCTTTGGAAAGTCTAGGTAAAACGGTTGCGACCTGTATTTTACCTGATGGCGAAAAGTATAAAGATATTCAGCATTTA
AACTTAATTTTTGATGCATTGCTTGAAGCTGGTTTTAACCGCGATTGTACGGTTTTAGCTTTAGGTGGTGGCGTCATTGG
TGATATGGCTGGTTTTGCTTCTGCTTGTTTCCAACGTGGCGTTTACTTTGTACAGGTTCCTACGACCTTACTTTCACAAG
TAGACTCAAGTGTTGGTGGAAAAACAGGAATTAATCATCCGCTTGGCAAGAATATGTTAGGTGCTTTTCAGCAACCACAA
GTCGTTTTAGCTGACATGGCACAATTGAATACGCTGCCAGAACGTGAGCTTTCGGCCGGTTTAGCCGAAGTAATTAAATA
TGCACTTTTAGGTGATGAAGATTTCTTGGTTTGGCTTGAAGAAAATATGGATGGCCTGGTTGCAAGAGATGCTGACCTTT
TAGCAGAGGCTGTTTATCGTTCATGTGCTCACAAAGCCCGCATTGTTGCCAATGATGAGAAAGAGCAAGGTGAACGTGCT
TTACTTAACTTAGGTCATACTTTTGGTCATGCGATTGAGTCGTATCTAGGTTATGGAACTTGGTTGCATGGTGAAGCTGT
AGCAACTGGAATGGTTATGGCGGCAGATTTATCACAACGTTTGGGTTGGATCTCAAATGAAGATGTGGCACGTACAAAAA
AAATCATTCAACGTGCAAATTTGCCGATATCATGTCCACAAATTCCATTGGATGATTTCCTTGGATATATGGCTCATGAC
AAAAAAGTTCTTAATGGGCAATTACGTTTGGTGTTGTTAAAACAACTCGGACAAGCTGTAATTACTAAGGACTTTGATGT
TGAACTTATGAAACAAGCTATTTTGGCGAATCAACACGGATAA

Upstream 100 bases:

>100_bases
ACGAATCAAGGTGCTGCACGTGATCTTGCCCAAAAGATTTTGCAACTTATTCTATCGAACAAGTTAAAATAGACGAACTG
ACTAGTGGTTTTATAAATTC

Downstream 100 bases:

>100_bases
CAAATAAGGTAAAGCATGACTGTATCACGTACACTTTGGCAGAATGTTCAACAATATATCTGGTTGGTTGGTGGTATTGT
CTGCTTATTCCTTGCTTTTA

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MQTLHVELGERRYPIFIGSQLDPKQLLEPYIHGQQVMIVSNVTVAPLYLSHYQEALESLGKTVATCILPDGEKYKDIQHL
NLIFDALLEAGFNRDCTVLALGGGVIGDMAGFASACFQRGVYFVQVPTTLLSQVDSSVGGKTGINHPLGKNMLGAFQQPQ
VVLADMAQLNTLPERELSAGLAEVIKYALLGDEDFLVWLEENMDGLVARDADLLAEAVYRSCAHKARIVANDEKEQGERA
LLNLGHTFGHAIESYLGYGTWLHGEAVATGMVMAADLSQRLGWISNEDVARTKKIIQRANLPISCPQIPLDDFLGYMAHD
KKVLNGQLRLVLLKQLGQAVITKDFDVELMKQAILANQHG

Sequences:

>Translated_360_residues
MQTLHVELGERRYPIFIGSQLDPKQLLEPYIHGQQVMIVSNVTVAPLYLSHYQEALESLGKTVATCILPDGEKYKDIQHL
NLIFDALLEAGFNRDCTVLALGGGVIGDMAGFASACFQRGVYFVQVPTTLLSQVDSSVGGKTGINHPLGKNMLGAFQQPQ
VVLADMAQLNTLPERELSAGLAEVIKYALLGDEDFLVWLEENMDGLVARDADLLAEAVYRSCAHKARIVANDEKEQGERA
LLNLGHTFGHAIESYLGYGTWLHGEAVATGMVMAADLSQRLGWISNEDVARTKKIIQRANLPISCPQIPLDDFLGYMAHD
KKVLNGQLRLVLLKQLGQAVITKDFDVELMKQAILANQHG
>Mature_360_residues
MQTLHVELGERRYPIFIGSQLDPKQLLEPYIHGQQVMIVSNVTVAPLYLSHYQEALESLGKTVATCILPDGEKYKDIQHL
NLIFDALLEAGFNRDCTVLALGGGVIGDMAGFASACFQRGVYFVQVPTTLLSQVDSSVGGKTGINHPLGKNMLGAFQQPQ
VVLADMAQLNTLPERELSAGLAEVIKYALLGDEDFLVWLEENMDGLVARDADLLAEAVYRSCAHKARIVANDEKEQGERA
LLNLGHTFGHAIESYLGYGTWLHGEAVATGMVMAADLSQRLGWISNEDVARTKKIIQRANLPISCPQIPLDDFLGYMAHD
KKVLNGQLRLVLLKQLGQAVITKDFDVELMKQAILANQHG

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=357, Percent_Identity=53.781512605042, Blast_Score=357, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320332, Length=340, Percent_Identity=38.2352941176471, Blast_Score=203, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_ACIB3 (B7GVP5)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002324258.1
- ProteinModelPortal:   B7GVP5
- SMR:   B7GVP5
- GeneID:   7059153
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_000325
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39494; Mature: 39494

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTLHVELGERRYPIFIGSQLDPKQLLEPYIHGQQVMIVSNVTVAPLYLSHYQEALESLG
CCEEEEECCCCCCCEEECCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHH
KTVATCILPDGEKYKDIQHLNLIFDALLEAGFNRDCTVLALGGGVIGDMAGFASACFQRG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
VYFVQVPTTLLSQVDSSVGGKTGINHPLGKNMLGAFQQPQVVLADMAQLNTLPERELSAG
EEEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHH
LAEVIKYALLGDEDFLVWLEENMDGLVARDADLLAEAVYRSCAHKARIVANDEKEQGERA
HHHHHHHHHCCCCCEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHH
LLNLGHTFGHAIESYLGYGTWLHGEAVATGMVMAADLSQRLGWISNEDVARTKKIIQRAN
HHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
LPISCPQIPLDDFLGYMAHDKKVLNGQLRLVLLKQLGQAVITKDFDVELMKQAILANQHG
CCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MQTLHVELGERRYPIFIGSQLDPKQLLEPYIHGQQVMIVSNVTVAPLYLSHYQEALESLG
CCEEEEECCCCCCCEEECCCCCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHH
KTVATCILPDGEKYKDIQHLNLIFDALLEAGFNRDCTVLALGGGVIGDMAGFASACFQRG
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCC
VYFVQVPTTLLSQVDSSVGGKTGINHPLGKNMLGAFQQPQVVLADMAQLNTLPERELSAG
EEEEEEHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHH
LAEVIKYALLGDEDFLVWLEENMDGLVARDADLLAEAVYRSCAHKARIVANDEKEQGERA
HHHHHHHHHCCCCCEEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHEEECCCHHHHHHH
LLNLGHTFGHAIESYLGYGTWLHGEAVATGMVMAADLSQRLGWISNEDVARTKKIIQRAN
HHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCC
LPISCPQIPLDDFLGYMAHDKKVLNGQLRLVLLKQLGQAVITKDFDVELMKQAILANQHG
CCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA