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The map label for this gene is lip [H]

Identifier: 213158913

GI number: 213158913

Start: 3720716

End: 3721690

Strand: Direct

Name: lip [H]

Synonym: AB57_3614

Alternate gene names: 213158913

Gene position: 3720716-3721690 (Clockwise)

Preceding gene: 213158912

Following gene: 213158926

Centisome position: 91.86

GC content: 43.49

Gene sequence:

>975_bases
ATGAAAAGGAACTTAATATTTTTCTGTGCTGCAATACTCTCAGGACTGAGTGTTTCAGCAACCCATGCCACAAATGCCGA
GCAAGTCAAAAGCTCATTCGTCTATTCGACTTATGCACAAACCAAATATCCATTGGTTTTTAACCATGGTATGGCGGGTT
TTAATCGAGTTGGAACAGATACGCTTGGTCTGGACTACTGGTATCAGATTCTTCCTGATCTTGCACGTAACGGAGGAAAT
GTCTGGGCAACAAGAGTTTCTCCGTTTAACTCAACTGAAGTTCGTGGAGAACAACTTGCCCAACAAGTAGAAGAAATTAT
TGCCATCACCGGAAAGCCTAAAGTCAACTTGATCGGACATAGCCACGGGGGACCTACAATTCGCTATGTCGCTGGGATCA
TGCCTGAAAAAGTCGCTTCACTTACTACTATTGGTGCACCTCACAAAGGATCGCCAATGGCAGATGTCATCCTGAATGTT
GAGGGTACTCCTCTATCCGGACTGGCAACATTAGTAAACTGGTTTTCCGCAGCAATTACTTGGGCAGGAGGTCTAGACCC
AAATAGTTATCCGCATGACTCCTTAGCAGGTGCCCACAGTTTATCGACTCAAGGCTCTGCACAGTTTAATTCTCAATTTC
CAATGGGTGTTCCTACCACGTCTTGTGGTGAGGGTGCTTACCAGGAGAAAGGCATTTATATGTATTCATTCTCTGGTAAT
AAAGCGCTGACGAACCCATTAGATCCATTTGATATAGCATTGACAGGAAGTAGTCTAGTGGTTGACCCATTTGGGGATAA
TGATGGGCTTGTGTCTCGATGCAGTGCCAAATTTGGTAAAACTATTCGTGACGACTATAACTGGAATCATTTAGATGAAG
TCAATCAGGTCATGGGAATACGTTCTATTTTTGCAGCAGACCCTGTATCGGTTTACCGTCAACATGCTAACCGTTTAAAA
CTTCAAGGATTATAA

Upstream 100 bases:

>100_bases
ACTACCCTTTAACTACTAGGCTTTTCTATTTCAAAGTGAGCCAAACCTTATCCAGCAGTAGAAGCTGCTTCTCATACAAA
ATAAAAATAGTGAGTAAAAA

Downstream 100 bases:

>100_bases
GCTTTAAAACAAAAAATGCGCCAAAAGGCGCATTTTTTACTCGCTATAAGCTTACGCTTTACGAGCTGGTAATTTTTCAC
GAATACGTGCAGCTTTACCA

Product: lipase

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKRNLIFFCAAILSGLSVSATHATNAEQVKSSFVYSTYAQTKYPLVFNHGMAGFNRVGTDTLGLDYWYQILPDLARNGGN
VWATRVSPFNSTEVRGEQLAQQVEEIIAITGKPKVNLIGHSHGGPTIRYVAGIMPEKVASLTTIGAPHKGSPMADVILNV
EGTPLSGLATLVNWFSAAITWAGGLDPNSYPHDSLAGAHSLSTQGSAQFNSQFPMGVPTTSCGEGAYQEKGIYMYSFSGN
KALTNPLDPFDIALTGSSLVVDPFGDNDGLVSRCSAKFGKTIRDDYNWNHLDEVNQVMGIRSIFAADPVSVYRQHANRLK
LQGL

Sequences:

>Translated_324_residues
MKRNLIFFCAAILSGLSVSATHATNAEQVKSSFVYSTYAQTKYPLVFNHGMAGFNRVGTDTLGLDYWYQILPDLARNGGN
VWATRVSPFNSTEVRGEQLAQQVEEIIAITGKPKVNLIGHSHGGPTIRYVAGIMPEKVASLTTIGAPHKGSPMADVILNV
EGTPLSGLATLVNWFSAAITWAGGLDPNSYPHDSLAGAHSLSTQGSAQFNSQFPMGVPTTSCGEGAYQEKGIYMYSFSGN
KALTNPLDPFDIALTGSSLVVDPFGDNDGLVSRCSAKFGKTIRDDYNWNHLDEVNQVMGIRSIFAADPVSVYRQHANRLK
LQGL
>Mature_324_residues
MKRNLIFFCAAILSGLSVSATHATNAEQVKSSFVYSTYAQTKYPLVFNHGMAGFNRVGTDTLGLDYWYQILPDLARNGGN
VWATRVSPFNSTEVRGEQLAQQVEEIIAITGKPKVNLIGHSHGGPTIRYVAGIMPEKVASLTTIGAPHKGSPMADVILNV
EGTPLSGLATLVNWFSAAITWAGGLDPNSYPHDSLAGAHSLSTQGSAQFNSQFPMGVPTTSCGEGAYQEKGIYMYSFSGN
KALTNPLDPFDIALTGSSLVVDPFGDNDGLVSRCSAKFGKTIRDDYNWNHLDEVNQVMGIRSIFAADPVSVYRQHANRLK
LQGL

Specific function: Catalyzes the hydrolysis of triglycerides. Catalyzes the synthesis of macrocyclic lactones in anhydrous organic solvents [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cell surface. Secreted, extracellular space. Note=During early stationary growth phase about 10% of the enzyme molecules remain cell-bound while about 90% are released into the growth medium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Pseudomonas lipase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 34896; Mature: 34896

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRNLIFFCAAILSGLSVSATHATNAEQVKSSFVYSTYAQTKYPLVFNHGMAGFNRVGTD
CCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHCCCC
TLGLDYWYQILPDLARNGGNVWATRVSPFNSTEVRGEQLAQQVEEIIAITGKPKVNLIGH
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEECCCCEEEEEEE
SHGGPTIRYVAGIMPEKVASLTTIGAPHKGSPMADVILNVEGTPLSGLATLVNWFSAAIT
CCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
WAGGLDPNSYPHDSLAGAHSLSTQGSAQFNSQFPMGVPTTSCGEGAYQEKGIYMYSFSGN
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEEECCC
KALTNPLDPFDIALTGSSLVVDPFGDNDGLVSRCSAKFGKTIRDDYNWNHLDEVNQVMGI
CCCCCCCCCCEEEEECCEEEEECCCCCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHH
RSIFAADPVSVYRQHANRLKLQGL
HHHHHCCHHHHHHHHHHCEECCCC
>Mature Secondary Structure
MKRNLIFFCAAILSGLSVSATHATNAEQVKSSFVYSTYAQTKYPLVFNHGMAGFNRVGTD
CCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHCCCC
TLGLDYWYQILPDLARNGGNVWATRVSPFNSTEVRGEQLAQQVEEIIAITGKPKVNLIGH
CCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEECCCCEEEEEEE
SHGGPTIRYVAGIMPEKVASLTTIGAPHKGSPMADVILNVEGTPLSGLATLVNWFSAAIT
CCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHH
WAGGLDPNSYPHDSLAGAHSLSTQGSAQFNSQFPMGVPTTSCGEGAYQEKGIYMYSFSGN
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEEEECCC
KALTNPLDPFDIALTGSSLVVDPFGDNDGLVSRCSAKFGKTIRDDYNWNHLDEVNQVMGI
CCCCCCCCCCEEEEECCEEEEECCCCCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHH
RSIFAADPVSVYRQHANRLKLQGL
HHHHHCCHHHHHHHHHHCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1512563; 1632642; 1576157; 10984043; 1748875; 11133953 [H]