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The map label for this gene is aroE [H]

Identifier: 213158864

GI number: 213158864

Start: 3666134

End: 3666922

Strand: Direct

Name: aroE [H]

Synonym: AB57_3561

Alternate gene names: 213158864

Gene position: 3666134-3666922 (Clockwise)

Preceding gene: 213158863

Following gene: 213158866

Centisome position: 90.51

GC content: 40.43

Gene sequence:

>789_bases
ATGACCAAACAGTTTGCAGTAATTGGCAATCCGATCGAACAATCACGCTCTCCTGAATTGCATCATGCTTTCGCTGAAAA
AACAGGTGTTGATCTAAACTATCAAAAACGGCTTGCTCCTCTTGACGGTTTTGAATCGAGCATGCGAAGTTTCTTTGCAG
AAGGCGGCAGTGGTATGAACGTTACTGTTCCTTTTAAAGAGCAAGCTTTTGCTTTATGTGATGTGTTAACCGAGCGTGCT
CAAATTGCTAAAGCTGTAAATACGTTATGGATGGAAAATGGCAAATTGCATGGTGACAATACAGACGGCCAAGGCTTAGT
TGCCGCAATTCAAGCTTTAGAGTGGAATCTTGAAAATACAACTATTTTAATTTTAGGAGCTGGCGGCGCAACTCGTGGTG
TTATTTATCCCCTTGTACAGGCTGGTGCCCAAAAAATCGTCATTGCAAACCGAACTTTAGCTCGTGCAGAACAACTTGTA
GATGACTTAAAAACAGCAGTTCCACAAGCCCAATTACAAGCAATTTCCCTAAATGATTTAGAAGGAGATTTTGATATTGT
GATTAATGCAACTTCGACAAGTCTGTCAGGCGATGCTTTACAACTACCTGAAAAATTACAATTCAAATATGCCTATGAAA
TGGCTTATGGCAAACCTTCTAGCTTCATTGATCAAGCGAAACAACGTAATGTGCCTTACGCAGAAGGTTTCGGCATGTTA
GTAGGCCAAGCTATTGAAGCCTTCTATATCTGGAATGGCGTACGACCACAATTAAAAGATTTTCTATAA

Upstream 100 bases:

>100_bases
AATATTTTTTCTTGTGCTATTTTGACTTATAGTGAGGCCTGCTGAATATTCAGTGCAGGCTCTATCTGCTTCATGCCATT
TTAAAATTTTGGATACAAGA

Downstream 100 bases:

>100_bases
ACCAAAAAAGAACCTACATATGTAGGTTCTTTTTTATCTTACTCATTATTTTTTAGCGGTAACCATTTGCTTATAAACTT
CTCGGAAAATTTCATAATCG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MTKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMNVTVPFKEQAFALCDVLTERA
QIAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENTTILILGAGGATRGVIYPLVQAGAQKIVIANRTLARAEQLV
DDLKTAVPQAQLQAISLNDLEGDFDIVINATSTSLSGDALQLPEKLQFKYAYEMAYGKPSSFIDQAKQRNVPYAEGFGML
VGQAIEAFYIWNGVRPQLKDFL

Sequences:

>Translated_262_residues
MTKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMNVTVPFKEQAFALCDVLTERA
QIAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENTTILILGAGGATRGVIYPLVQAGAQKIVIANRTLARAEQLV
DDLKTAVPQAQLQAISLNDLEGDFDIVINATSTSLSGDALQLPEKLQFKYAYEMAYGKPSSFIDQAKQRNVPYAEGFGML
VGQAIEAFYIWNGVRPQLKDFL
>Mature_261_residues
TKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMNVTVPFKEQAFALCDVLTERAQ
IAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENTTILILGAGGATRGVIYPLVQAGAQKIVIANRTLARAEQLVD
DLKTAVPQAQLQAISLNDLEGDFDIVINATSTSLSGDALQLPEKLQFKYAYEMAYGKPSSFIDQAKQRNVPYAEGFGMLV
GQAIEAFYIWNGVRPQLKDFL

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789675, Length=263, Percent_Identity=44.8669201520913, Blast_Score=214, Evalue=4e-57,
Organism=Escherichia coli, GI1787983, Length=283, Percent_Identity=29.6819787985866, Blast_Score=93, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320332, Length=284, Percent_Identity=28.5211267605634, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 28614; Mature: 28483

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMN
CCCCEEEECCCHHHCCCCHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCE
VTVPFKEQAFALCDVLTERAQIAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENT
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHCCCCCC
TILILGAGGATRGVIYPLVQAGAQKIVIANRTLARAEQLVDDLKTAVPQAQLQAISLNDL
EEEEEECCCCCCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCHHHEEEEECCCC
EGDFDIVINATSTSLSGDALQLPEKLQFKYAYEMAYGKPSSFIDQAKQRNVPYAEGFGML
CCCEEEEEEECCCCCCCCHHHCCHHHHHHEEEEHHCCCCHHHHHHHHHCCCCCHHHHHHH
VGQAIEAFYIWNGVRPQLKDFL
HHHHHHHHHEECCCCHHHHHCC
>Mature Secondary Structure 
TKQFAVIGNPIEQSRSPELHHAFAEKTGVDLNYQKRLAPLDGFESSMRSFFAEGGSGMN
CCCEEEECCCHHHCCCCHHHHHHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCE
VTVPFKEQAFALCDVLTERAQIAKAVNTLWMENGKLHGDNTDGQGLVAAIQALEWNLENT
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHCCCCCC
TILILGAGGATRGVIYPLVQAGAQKIVIANRTLARAEQLVDDLKTAVPQAQLQAISLNDL
EEEEEECCCCCCHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCHHHEEEEECCCC
EGDFDIVINATSTSLSGDALQLPEKLQFKYAYEMAYGKPSSFIDQAKQRNVPYAEGFGML
CCCEEEEEEECCCCCCCCHHHCCHHHHHHEEEEHHCCCCHHHHHHHHHCCCCCHHHHHHH
VGQAIEAFYIWNGVRPQLKDFL
HHHHHHHHHEECCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA