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The map label for this gene is hcaR [C]

Identifier: 213158774

GI number: 213158774

Start: 4032945

End: 4033835

Strand: Direct

Name: hcaR [C]

Synonym: AB57_3908

Alternate gene names: 213158774

Gene position: 4032945-4033835 (Clockwise)

Preceding gene: 213158773

Following gene: 213158778

Centisome position: 99.57

GC content: 41.64

Gene sequence:

>891_bases
ATGCGTTTTGATTTTTTTGATTTACAGCTGGTTCTTCATATTGTCTCGACTGGTAGCCTCACCAAAGGCGCTGACCGCTC
TGCGATTTCACTTCAAGCGGCGAGTGAACGTATAAAAAAACTTGAACAGTATTTTGAGACTCCTTTATTTATTCGCCAAA
CCACAGGTGTAGAACTCACTACAGCTGGACATGCATTTGTAGAACATGCTCGTCAGCTTTTAGCTCAAAAAGATCAACTC
GAACACGAAATGCAGCGGTTCAGACAGCCGACAACAGAAGCATTAACACTTTGGTGTAACTCATCTGCTCAAAGTGAATA
TCTACCTACCTTATTACCGCAATATCTAGTGCTTCATCCCGAAATGAATATCGATTTGCATGAAGCAGAAAGTTCAGAAA
TTGTAGATGCATTAACCCAAGGGATTGCAAGTCTTGGCCTAGTTTCGAGTTTTTTCAATACCCGACATTTGCAAACTAAA
GAGTTTGCAAGCGACCCATTAGTACTTATTTGCCCTGTGACACATGAGTTAGCCCACTACAAAGAGCTAAATTTAGTAGA
TGCTTTAAGCTATGGTTTTATTGGACTCAAATCGCATCACTCTTTACAACAGTCCATTGAAACCCAAGCCAAATTATTAG
GCTTTAATATACAGTATCGGTTGCGCTTACCTAACTTTGGCGCAATTGCCGAGGTAGTCGCCAAAGGTGTGGGAATTGCG
ATTATGCCTGCCCGTGCTGCACAGCGCCTACAATCGGACTATGATTTTCATTCAATTCAACTGCTAGGCGCATGGGCAAA
CCGTAAACTACTTTTGGCCACACAAAGTTTCAATCAGTTGCCTAGTAGTTACCAACAGTTTGCAGACTTTTTATTGCAAC
ATCGTCCTTAA

Upstream 100 bases:

>100_bases
AGTTTAAAAGATAAAACCTAAATTCTAAAAGGCAGCGCAAGCTGCCTTTTTTCATTCCGATTTAGTATGATGAATTTTTG
CATTTCAATACGTTCCTATC

Downstream 100 bases:

>100_bases
AAATTAAACTTAATGCAAAATCATATAAAGTCCTAATGACATCAAGCCTATAAAAAAGATACGGCGAAAAATCTGCTCAT
TCAGTCGATAGCGGATTTTT

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MRFDFFDLQLVLHIVSTGSLTKGADRSAISLQAASERIKKLEQYFETPLFIRQTTGVELTTAGHAFVEHARQLLAQKDQL
EHEMQRFRQPTTEALTLWCNSSAQSEYLPTLLPQYLVLHPEMNIDLHEAESSEIVDALTQGIASLGLVSSFFNTRHLQTK
EFASDPLVLICPVTHELAHYKELNLVDALSYGFIGLKSHHSLQQSIETQAKLLGFNIQYRLRLPNFGAIAEVVAKGVGIA
IMPARAAQRLQSDYDFHSIQLLGAWANRKLLLATQSFNQLPSSYQQFADFLLQHRP

Sequences:

>Translated_296_residues
MRFDFFDLQLVLHIVSTGSLTKGADRSAISLQAASERIKKLEQYFETPLFIRQTTGVELTTAGHAFVEHARQLLAQKDQL
EHEMQRFRQPTTEALTLWCNSSAQSEYLPTLLPQYLVLHPEMNIDLHEAESSEIVDALTQGIASLGLVSSFFNTRHLQTK
EFASDPLVLICPVTHELAHYKELNLVDALSYGFIGLKSHHSLQQSIETQAKLLGFNIQYRLRLPNFGAIAEVVAKGVGIA
IMPARAAQRLQSDYDFHSIQLLGAWANRKLLLATQSFNQLPSSYQQFADFLLQHRP
>Mature_296_residues
MRFDFFDLQLVLHIVSTGSLTKGADRSAISLQAASERIKKLEQYFETPLFIRQTTGVELTTAGHAFVEHARQLLAQKDQL
EHEMQRFRQPTTEALTLWCNSSAQSEYLPTLLPQYLVLHPEMNIDLHEAESSEIVDALTQGIASLGLVSSFFNTRHLQTK
EFASDPLVLICPVTHELAHYKELNLVDALSYGFIGLKSHHSLQQSIETQAKLLGFNIQYRLRLPNFGAIAEVVAKGVGIA
IMPARAAQRLQSDYDFHSIQLLGAWANRKLLLATQSFNQLPSSYQQFADFLLQHRP

Specific function: Transcriptional Activator Of The Hca Operon For 3- Phenylpropionic Acid Catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=273, Percent_Identity=24.5421245421245, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=21.5447154471545, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33374; Mature: 33374

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDFFDLQLVLHIVSTGSLTKGADRSAISLQAASERIKKLEQYFETPLFIRQTTGVELT
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEE
TAGHAFVEHARQLLAQKDQLEHEMQRFRQPTTEALTLWCNSSAQSEYLPTLLPQYLVLHP
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCHHHHHHHHHHHEECC
EMNIDLHEAESSEIVDALTQGIASLGLVSSFFNTRHLQTKEFASDPLVLICPVTHELAHY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCHHHHHHH
KELNLVDALSYGFIGLKSHHSLQQSIETQAKLLGFNIQYRLRLPNFGAIAEVVAKGVGIA
HHCCHHHHHHHCCEECCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCEE
IMPARAAQRLQSDYDFHSIQLLGAWANRKLLLATQSFNQLPSSYQQFADFLLQHRP
EECHHHHHHHHCCCCHHEEEEEEECCCCEEEEEECHHHHCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFDFFDLQLVLHIVSTGSLTKGADRSAISLQAASERIKKLEQYFETPLFIRQTTGVELT
CCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEE
TAGHAFVEHARQLLAQKDQLEHEMQRFRQPTTEALTLWCNSSAQSEYLPTLLPQYLVLHP
ECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCHHHHHHHHHHHEECC
EMNIDLHEAESSEIVDALTQGIASLGLVSSFFNTRHLQTKEFASDPLVLICPVTHELAHY
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCHHHHHHH
KELNLVDALSYGFIGLKSHHSLQQSIETQAKLLGFNIQYRLRLPNFGAIAEVVAKGVGIA
HHCCHHHHHHHCCEECCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCEE
IMPARAAQRLQSDYDFHSIQLLGAWANRKLLLATQSFNQLPSSYQQFADFLLQHRP
EECHHHHHHHHCCCCHHEEEEEEECCCCEEEEEECHHHHCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]