Click here to switch to the map view.

The map label for this gene is ppnK [H]

Identifier: 213158683

GI number: 213158683

Start: 2726584

End: 2727492

Strand: Reverse

Name: ppnK [H]

Synonym: AB57_2637

Alternate gene names: 213158683

Gene position: 2727492-2726584 (Counterclockwise)

Preceding gene: 213158685

Following gene: 213158682

Centisome position: 67.34

GC content: 40.48

Gene sequence:

>909_bases
GTGCAAATTTCACATAAGTCCTTCAGAAACGTCGGGTTAATTGGTCGACCAGATAAATCATCAGTTGTAGAAACACTATG
TTTAATTCATGACCATTTGCTAAGTTTAGGCCTAAACCCCATTTTTGATCAGGAAACTGCCGAATTAGTGCCCTATGATC
ATGCGCAAGTCGTTAGTCGTCACTTATTAGGTGAAGTCGCTGATCTGGTGATTGTTGTAGGTGGTGACGGTTCATTGCTT
CATGCAGCCAGAGCTTTAGTTCGCTACAATACGCCCGTAATCGGGATTAACCGTGGACGTTTAGGTTTTTTAACCGATAT
TAAGCCTTCGGAAGCTATTTTTAAGCTTGATCAGGTTTTACAAGGTCATTTCCAGCTTGATCGCCGTTTCTTGCTTGAAA
TGGAAGTACGTACTAATGGTGAAGTCATTTATGATGCAATTGCTTTAAATGACGTCGTACTACACTCTGGTAAGTCGGTA
CATATGATCGATTTTGAACTCAATATCGATGGGCAATATGTTTATCGCCAGCATAGTGATGGTTTAATTGTTTCGACACC
AACCGGTTCAACTGCTTATGCTTTATCAGGTGGTGGACCAATTTTACATCCAAGTATGGATGCTATTGCATTAGTTCCTA
TGCATCCCCATACATTATCTTCACGCCCGATCGTAGTTGGTGGGCAAAGTGAAATTAAAATCGTCATTCGCGAAAATCGG
GTATTACCGATGGTAAGTGCAGATGGACAACATAGTGTCTCTCTCAATGTCGGTGATAGTTTGCACATCCGCAAACACCC
ATTTAAATTAAGTTTATTACACCCACCTGGTTATGATTTCTATATGGCTTGTCGTACCAAATTGGGTTGGAACCAAGATT
TTGAATCTTTTCAAAGAGATGAATCATGA

Upstream 100 bases:

>100_bases
AAACTTAGATTGAATTTTACAGTATCTTGTTGTTATGTTTTTTTAAATTAATCTGGTTAATGTTATGATAGCGTAGAATC
GCAGCGGAGCTTACTCATTC

Downstream 100 bases:

>100_bases
ATATTGAACAAATGCTATCTGTTTTAAACCCTGAGATTGTAGAGCGTTTAAAAACAGCAGTAGAAATTGGTAAATGGCCA
AATGGTGTTGCTTTAACGAA

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MQISHKSFRNVGLIGRPDKSSVVETLCLIHDHLLSLGLNPIFDQETAELVPYDHAQVVSRHLLGEVADLVIVVGGDGSLL
HAARALVRYNTPVIGINRGRLGFLTDIKPSEAIFKLDQVLQGHFQLDRRFLLEMEVRTNGEVIYDAIALNDVVLHSGKSV
HMIDFELNIDGQYVYRQHSDGLIVSTPTGSTAYALSGGGPILHPSMDAIALVPMHPHTLSSRPIVVGGQSEIKIVIRENR
VLPMVSADGQHSVSLNVGDSLHIRKHPFKLSLLHPPGYDFYMACRTKLGWNQDFESFQRDES

Sequences:

>Translated_302_residues
MQISHKSFRNVGLIGRPDKSSVVETLCLIHDHLLSLGLNPIFDQETAELVPYDHAQVVSRHLLGEVADLVIVVGGDGSLL
HAARALVRYNTPVIGINRGRLGFLTDIKPSEAIFKLDQVLQGHFQLDRRFLLEMEVRTNGEVIYDAIALNDVVLHSGKSV
HMIDFELNIDGQYVYRQHSDGLIVSTPTGSTAYALSGGGPILHPSMDAIALVPMHPHTLSSRPIVVGGQSEIKIVIRENR
VLPMVSADGQHSVSLNVGDSLHIRKHPFKLSLLHPPGYDFYMACRTKLGWNQDFESFQRDES
>Mature_302_residues
MQISHKSFRNVGLIGRPDKSSVVETLCLIHDHLLSLGLNPIFDQETAELVPYDHAQVVSRHLLGEVADLVIVVGGDGSLL
HAARALVRYNTPVIGINRGRLGFLTDIKPSEAIFKLDQVLQGHFQLDRRFLLEMEVRTNGEVIYDAIALNDVVLHSGKSV
HMIDFELNIDGQYVYRQHSDGLIVSTPTGSTAYALSGGGPILHPSMDAIALVPMHPHTLSSRPIVVGGQSEIKIVIRENR
VLPMVSADGQHSVSLNVGDSLHIRKHPFKLSLLHPPGYDFYMACRTKLGWNQDFESFQRDES

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=253, Percent_Identity=31.6205533596838, Blast_Score=101, Evalue=7e-22,
Organism=Escherichia coli, GI1788968, Length=287, Percent_Identity=43.9024390243902, Blast_Score=251, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI71999610, Length=157, Percent_Identity=33.1210191082803, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320794, Length=258, Percent_Identity=32.1705426356589, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322509, Length=240, Percent_Identity=32.0833333333333, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6325068, Length=210, Percent_Identity=34.2857142857143, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI28573828, Length=253, Percent_Identity=35.5731225296443, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28573826, Length=253, Percent_Identity=35.5731225296443, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI28573832, Length=253, Percent_Identity=35.5731225296443, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI161077047, Length=253, Percent_Identity=35.5731225296443, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI28573830, Length=253, Percent_Identity=35.5731225296443, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24653422, Length=278, Percent_Identity=30.9352517985612, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI20129957, Length=278, Percent_Identity=30.9352517985612, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281363323, Length=278, Percent_Identity=30.9352517985612, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI281363321, Length=248, Percent_Identity=32.6612903225806, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24653424, Length=278, Percent_Identity=30.9352517985612, Blast_Score=104, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 33416; Mature: 33416

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQISHKSFRNVGLIGRPDKSSVVETLCLIHDHLLSLGLNPIFDQETAELVPYDHAQVVSR
CCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHH
HLLGEVADLVIVVGGDGSLLHAARALVRYNTPVIGINRGRLGFLTDIKPSEAIFKLDQVL
HHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHH
QGHFQLDRRFLLEMEVRTNGEVIYDAIALNDVVLHSGKSVHMIDFELNIDGQYVYRQHSD
HHHHHHCEEEEEEEEECCCCCEEEEEEECCEEEEECCCEEEEEEEEEECCCEEEEEECCC
GLIVSTPTGSTAYALSGGGPILHPSMDAIALVPMHPHTLSSRPIVVGGQSEIKIVIRENR
CEEEECCCCCEEEEEECCCCEECCCCCEEEEEECCCCCCCCCCEEEECCCEEEEEEECCC
VLPMVSADGQHSVSLNVGDSLHIRKHPFKLSLLHPPGYDFYMACRTKLGWNQDFESFQRD
EEEEEECCCCEEEEEECCCEEEEEECCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHCC
ES
CC
>Mature Secondary Structure
MQISHKSFRNVGLIGRPDKSSVVETLCLIHDHLLSLGLNPIFDQETAELVPYDHAQVVSR
CCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHH
HLLGEVADLVIVVGGDGSLLHAARALVRYNTPVIGINRGRLGFLTDIKPSEAIFKLDQVL
HHHHHHEEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHH
QGHFQLDRRFLLEMEVRTNGEVIYDAIALNDVVLHSGKSVHMIDFELNIDGQYVYRQHSD
HHHHHHCEEEEEEEEECCCCCEEEEEEECCEEEEECCCEEEEEEEEEECCCEEEEEECCC
GLIVSTPTGSTAYALSGGGPILHPSMDAIALVPMHPHTLSSRPIVVGGQSEIKIVIRENR
CEEEECCCCCEEEEEECCCCEECCCCCEEEEEECCCCCCCCCCEEEECCCEEEEEEECCC
VLPMVSADGQHSVSLNVGDSLHIRKHPFKLSLLHPPGYDFYMACRTKLGWNQDFESFQRD
EEEEEECCCCEEEEEECCCEEEEEECCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHCC
ES
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA