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The map label for this gene is gcp [H]

Identifier: 213158646

GI number: 213158646

Start: 2692684

End: 2693694

Strand: Reverse

Name: gcp [H]

Synonym: AB57_2600

Alternate gene names: 213158646

Gene position: 2693694-2692684 (Counterclockwise)

Preceding gene: 213158649

Following gene: 213158643

Centisome position: 66.5

GC content: 41.54

Gene sequence:

>1011_bases
ATGATTGTTTTAGGCTTGGAAACTTCTTGTGATGAAACAGGGTTGGCACTTTATGATAGCGAACTCGGCTTACGGGGACA
GGTTCTTTATAGCCAGATAAAACTTCATGCCGAATATGGTGGTGTGGTTCCAGAGTTAGCTTCTCGTGACCATGTTCGTA
AGCTTATTCCTTTAATGAATCAGCTGCTTGAACAAAGTGGTGTTAAGAAACAGGAAATTGATGCAGTCGCATATACGCGT
GGCCCGGGTTTAATGGGAGCGTTAATGACCGGAGCTTTGTTTGGAAGAACTTTAGCATTTTCTTTAAATAAACCGGCAAT
TGGTGTTCACCACATGGAAGGCCATATGTTGGCTCCTTTGCTTTCAAGCCAACCGCCTGAGTTTCCATTTGTTGCATTGC
TTGTTTCAGGTGGTCATACACAATTGATGGCAGCTCATGGTATTGGTCAATATGAGCTATTAGGTGAGTCAATTGATGAT
GCGGCAGGTGAGGCTTTCGACAAAGTCGCAAAAATGATGAATCTGCCGTATCCAGGTGGACCAAATATTGCTAAGTTGGC
GTTATCTGGTGATCCTTTAGCATTTGAATTTCCACGCCCAATGCTTCATCAGGGCTTAGACTTTTCTTTTAGTGGTTTAA
AGACGGCAGTTTCTGTTCAGTTGAAAAAATTGAACGGCGAAAATCGTGATGCTGATATTGCTGCCTCATTCCAAGAAGCA
ATTGTAGACACCTTAGTAAAAAAATCTGTAAAAGCTTTAAAGCAAACTGGGCTTAAACGTTTAGTAATTGCTGGTGGGGT
AAGTGCAAATTTACGATTACGTGAACAGTTGGAAACTTCATTGGCGAAAATTAAAGCTCAGGTTTACTATGCAGAACCTG
CTTTATGTACTGATAATGGTGCAATGATTGCATTTGCAGGTTATCAGCGTTTAAAAGCAGGTCAGCATGATGGTTTAGCT
GTAACGACCACACCAAGATGGCCAATGACTGAACTTACTATTCCTGAGTAA

Upstream 100 bases:

>100_bases
CAGATCACAAGTGAAGGTCAGTATTTTACTCATTTACAACTCATATCACAAGTCTATAATAGCGATTGCAATATTTTGAC
TCATATAAAAGGCAGTTTTG

Downstream 100 bases:

>100_bases
GATTATTCATCTTCAAAGGCTTTAGGATTTTCGATATCAATATATTCGATGTATCCACGACCTTGAACTTCATTGCCAAA
ATAATGACCAGTAAATATAT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MIVLGLETSCDETGLALYDSELGLRGQVLYSQIKLHAEYGGVVPELASRDHVRKLIPLMNQLLEQSGVKKQEIDAVAYTR
GPGLMGALMTGALFGRTLAFSLNKPAIGVHHMEGHMLAPLLSSQPPEFPFVALLVSGGHTQLMAAHGIGQYELLGESIDD
AAGEAFDKVAKMMNLPYPGGPNIAKLALSGDPLAFEFPRPMLHQGLDFSFSGLKTAVSVQLKKLNGENRDADIAASFQEA
IVDTLVKKSVKALKQTGLKRLVIAGGVSANLRLREQLETSLAKIKAQVYYAEPALCTDNGAMIAFAGYQRLKAGQHDGLA
VTTTPRWPMTELTIPE

Sequences:

>Translated_336_residues
MIVLGLETSCDETGLALYDSELGLRGQVLYSQIKLHAEYGGVVPELASRDHVRKLIPLMNQLLEQSGVKKQEIDAVAYTR
GPGLMGALMTGALFGRTLAFSLNKPAIGVHHMEGHMLAPLLSSQPPEFPFVALLVSGGHTQLMAAHGIGQYELLGESIDD
AAGEAFDKVAKMMNLPYPGGPNIAKLALSGDPLAFEFPRPMLHQGLDFSFSGLKTAVSVQLKKLNGENRDADIAASFQEA
IVDTLVKKSVKALKQTGLKRLVIAGGVSANLRLREQLETSLAKIKAQVYYAEPALCTDNGAMIAFAGYQRLKAGQHDGLA
VTTTPRWPMTELTIPE
>Mature_336_residues
MIVLGLETSCDETGLALYDSELGLRGQVLYSQIKLHAEYGGVVPELASRDHVRKLIPLMNQLLEQSGVKKQEIDAVAYTR
GPGLMGALMTGALFGRTLAFSLNKPAIGVHHMEGHMLAPLLSSQPPEFPFVALLVSGGHTQLMAAHGIGQYELLGESIDD
AAGEAFDKVAKMMNLPYPGGPNIAKLALSGDPLAFEFPRPMLHQGLDFSFSGLKTAVSVQLKKLNGENRDADIAASFQEA
IVDTLVKKSVKALKQTGLKRLVIAGGVSANLRLREQLETSLAKIKAQVYYAEPALCTDNGAMIAFAGYQRLKAGQHDGLA
VTTTPRWPMTELTIPE

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=356, Percent_Identity=36.5168539325843, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI8923380, Length=341, Percent_Identity=32.8445747800587, Blast_Score=162, Evalue=3e-40,
Organism=Escherichia coli, GI1789445, Length=335, Percent_Identity=62.6865671641791, Blast_Score=424, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI71995670, Length=338, Percent_Identity=33.1360946745562, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17557464, Length=323, Percent_Identity=30.6501547987616, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6320099, Length=366, Percent_Identity=32.7868852459016, Blast_Score=179, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6322891, Length=351, Percent_Identity=27.6353276353276, Blast_Score=127, Evalue=2e-30,
Organism=Drosophila melanogaster, GI20129063, Length=340, Percent_Identity=34.4117647058824, Blast_Score=188, Evalue=4e-48,
Organism=Drosophila melanogaster, GI21357207, Length=335, Percent_Identity=29.5522388059701, Blast_Score=141, Evalue=6e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36104; Mature: 36104

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVLGLETSCDETGLALYDSELGLRGQVLYSQIKLHAEYGGVVPELASRDHVRKLIPLMN
CEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHH
QLLEQSGVKKQEIDAVAYTRGPGLMGALMTGALFGRTLAFSLNKPAIGVHHMEGHMLAPL
HHHHHHCCCHHHHCEEEEECCCCHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCHHHH
LSSQPPEFPFVALLVSGGHTQLMAAHGIGQYELLGESIDDAAGEAFDKVAKMMNLPYPGG
HCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
PNIAKLALSGDPLAFEFPRPMLHQGLDFSFSGLKTAVSVQLKKLNGENRDADIAASFQEA
CCEEEEEECCCCEEEECCCHHHHCCCCCCHHHHHHHHHEEEEECCCCCCCCHHHHHHHHH
IVDTLVKKSVKALKQTGLKRLVIAGGVSANLRLREQLETSLAKIKAQVYYAEPALCTDNG
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEECCCEECCCC
AMIAFAGYQRLKAGQHDGLAVTTTPRWPMTELTIPE
CEEEEECHHHHHCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MIVLGLETSCDETGLALYDSELGLRGQVLYSQIKLHAEYGGVVPELASRDHVRKLIPLMN
CEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHCHHHHHHHHHHHH
QLLEQSGVKKQEIDAVAYTRGPGLMGALMTGALFGRTLAFSLNKPAIGVHHMEGHMLAPL
HHHHHHCCCHHHHCEEEEECCCCHHHHHHHHHHHHHHEEEECCCCCEEEEECCCCCHHHH
LSSQPPEFPFVALLVSGGHTQLMAAHGIGQYELLGESIDDAAGEAFDKVAKMMNLPYPGG
HCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
PNIAKLALSGDPLAFEFPRPMLHQGLDFSFSGLKTAVSVQLKKLNGENRDADIAASFQEA
CCEEEEEECCCCEEEECCCHHHHCCCCCCHHHHHHHHHEEEEECCCCCCCCHHHHHHHHH
IVDTLVKKSVKALKQTGLKRLVIAGGVSANLRLREQLETSLAKIKAQVYYAEPALCTDNG
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEEEEECCCEECCCC
AMIAFAGYQRLKAGQHDGLAVTTTPRWPMTELTIPE
CEEEEECHHHHHCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA