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The map label for this gene is 213158480

Identifier: 213158480

GI number: 213158480

Start: 2516071

End: 2517783

Strand: Reverse

Name: 213158480

Synonym: AB57_2429

Alternate gene names: NA

Gene position: 2517783-2516071 (Counterclockwise)

Preceding gene: 213158482

Following gene: 213158479

Centisome position: 62.16

GC content: 39.11

Gene sequence:

>1713_bases
ATGAAACAGGAAACTGCACTTAAACTGCTAAAAGCAGGTGAAAATGTTTTTTTAACCGGTTCGGCTGGTGCAGGGAAAAC
CTATACACTCAATCAGTACATCCATTATTTAAAAGCGCGTAAAGTACCTGTAGCGATTACAGCATCTACCGGTATTGCTG
CAACGCATATGAATGGCATGACAATTCATACATGGGCTGGTATTGGCATCAAAGATCATCTAACTGACGATGACTTGAAA
CGCATGAAAGAGCGTAAATATCTCAAGGAACATCTTGAAAACGCGCAAGTTCTTGTGATTGATGAAATCTCAATGCTCCA
TGCGAAGCAACTTAATCTGGTCAATCAGGTTTTAAAATATTTTAAAGAAAGTGATGAAGCATTCGGTGGCATTCAAGTGA
TTGTAGCTGGAGATTTCTTCCAGTTGCCACCCGTAGGCCGTAATGGTGAAGCCAATCGTGACAAGTTCTGTTTTATGTCT
GATGCATGGGTCGAAGCCAAATTTCGGGTATGTTATTTAACAGAACAACACCGCCAAGATGATGAAATTCTGAATCAGAT
ATTAAATGCGATTCGTGCGCAAAGTATTCAAACCGAGCATTTGCAAGCTTTGCATCAATCCCGTACTCATGACATTGGCG
AAACCTTTACTCGTCTTTATACGCATAACATGGATGTCGATAATATCAATTATCAGCACTTAAACGAAATTGATAACGAA
GGGCATCAATTTAATGCCGTTTTAGACGGTAATGAAAAGTTATTAGAGACCTTAAAATCTTCAGTCCGTGCTCCGGAAGA
ACTCACACTTAAAAAACATGCCAAAGTGATGTTTGTAAAAAACAACTTTGATATGGGTTATATCAACGGAAGTTTAGGTG
AGGTGATCGGTTTTGAAGAAGATGACGAAAATGGGTTATTGCCAAAGGTAAAATTAACCGATGGTACAACTTTGCTGGTA
GCGCCTGAAACATGGTCAATTGAAAATGAAGCAGGAAAAGTCATTGCAAGTTTCCAGCAAATTCCACTTCGTTTGGCGTG
GGCGATTACCATTCATAAAAGCCAAGGTATGACTTTGGAAGCTGCCGAAATTAACCTGATGCATACCTTTGAAAAAGGGC
AAGGTTATGTTGCGCTCTCACGTTTGAAGTCTTTAACAGGGTTAAAATTATTAGGTTTTAATGAACAAGCTTTGGAGTTA
GATAGTCTGGCTGTAAAAGCTGATCGCCGTTTTCAAGAACTTTCTAAAGAAGCCGAAGATAATTTTGCTAATGTCGATTT
AACGGCTCAACATAAAGCCTTTATTCGTCATTGTGGTGGAACCTTAAATGAAACTGAAATTTCAAGGAATGAGAAAAAAC
TAGCGAGAGGCGAGAAGCAAAATTACGCCTCAGCGACTTTGGACGAAACTCGTGCATTGTTTGAAGAAGGCTACGAAATT
GAAGATATTGCACATGAACGTGGTCTAACACCTGCAACCATTATTAATCACTTGGCTCGACTGCATAAAGAACAAAAGCT
AGATATTTCGGTTGCCCATCCTGGTGAAGAAGTGGTCGAAGAAGTGCGTAAAATTTATAAGAAGTTGAAAAAACGCCAAA
ATCCGGATCATTTTTCTGATGATGGTTCGATCAAACTAAGACCAATTGTTGAAGCAACCAGCCCTCGAATGGGATATGAT
CAGGTTCGATTAGCTTTATTATTTATTGAATAA

Upstream 100 bases:

>100_bases
TATTGATTTATATTGTTTTTATAGAAAATTTGGCTCATTCATTTAAATTTTTCGGGAAAATCGTTAAGCTATGGGCTGTT
GAAGATGTACATATGAGATT

Downstream 100 bases:

>100_bases
AGTTTAATTGGCTTAATGACTTATTATATAAATTGAGGTGGCTATGCCGCACGTTGTAGTTGATTATTCAGATAACTTAA
CTGGACTAAATGCAAAACAA

Product: putative helicase

Products: NA

Alternate protein names: Helicase; TPR Domain Protein; TPR Domain-Containing Protein; ATPase; Exonuclease V Subunit Alpha; 5-3' DNA Helicase; Helicase-Related Protein; Aaa ATPase; Glycosysltransferase; Hrdc Domain Protein; Helicase-Family Protein; Helicase Protein; HRDC Domain Protein; RecD-Like Exodeoxyribonuclease V Alpha Chain; RRM3/PIF1 Helicase-Like Protein; ATP-Dependent ExoDNAse Alpha Subunit; DNA Helicase AAA ATPase; DNA Helicase/AAA ATPase; Helicase RecD/TraA Family

Number of amino acids: Translated: 570; Mature: 570

Protein sequence:

>570_residues
MKQETALKLLKAGENVFLTGSAGAGKTYTLNQYIHYLKARKVPVAITASTGIAATHMNGMTIHTWAGIGIKDHLTDDDLK
RMKERKYLKEHLENAQVLVIDEISMLHAKQLNLVNQVLKYFKESDEAFGGIQVIVAGDFFQLPPVGRNGEANRDKFCFMS
DAWVEAKFRVCYLTEQHRQDDEILNQILNAIRAQSIQTEHLQALHQSRTHDIGETFTRLYTHNMDVDNINYQHLNEIDNE
GHQFNAVLDGNEKLLETLKSSVRAPEELTLKKHAKVMFVKNNFDMGYINGSLGEVIGFEEDDENGLLPKVKLTDGTTLLV
APETWSIENEAGKVIASFQQIPLRLAWAITIHKSQGMTLEAAEINLMHTFEKGQGYVALSRLKSLTGLKLLGFNEQALEL
DSLAVKADRRFQELSKEAEDNFANVDLTAQHKAFIRHCGGTLNETEISRNEKKLARGEKQNYASATLDETRALFEEGYEI
EDIAHERGLTPATIINHLARLHKEQKLDISVAHPGEEVVEEVRKIYKKLKKRQNPDHFSDDGSIKLRPIVEATSPRMGYD
QVRLALLFIE

Sequences:

>Translated_570_residues
MKQETALKLLKAGENVFLTGSAGAGKTYTLNQYIHYLKARKVPVAITASTGIAATHMNGMTIHTWAGIGIKDHLTDDDLK
RMKERKYLKEHLENAQVLVIDEISMLHAKQLNLVNQVLKYFKESDEAFGGIQVIVAGDFFQLPPVGRNGEANRDKFCFMS
DAWVEAKFRVCYLTEQHRQDDEILNQILNAIRAQSIQTEHLQALHQSRTHDIGETFTRLYTHNMDVDNINYQHLNEIDNE
GHQFNAVLDGNEKLLETLKSSVRAPEELTLKKHAKVMFVKNNFDMGYINGSLGEVIGFEEDDENGLLPKVKLTDGTTLLV
APETWSIENEAGKVIASFQQIPLRLAWAITIHKSQGMTLEAAEINLMHTFEKGQGYVALSRLKSLTGLKLLGFNEQALEL
DSLAVKADRRFQELSKEAEDNFANVDLTAQHKAFIRHCGGTLNETEISRNEKKLARGEKQNYASATLDETRALFEEGYEI
EDIAHERGLTPATIINHLARLHKEQKLDISVAHPGEEVVEEVRKIYKKLKKRQNPDHFSDDGSIKLRPIVEATSPRMGYD
QVRLALLFIE
>Mature_570_residues
MKQETALKLLKAGENVFLTGSAGAGKTYTLNQYIHYLKARKVPVAITASTGIAATHMNGMTIHTWAGIGIKDHLTDDDLK
RMKERKYLKEHLENAQVLVIDEISMLHAKQLNLVNQVLKYFKESDEAFGGIQVIVAGDFFQLPPVGRNGEANRDKFCFMS
DAWVEAKFRVCYLTEQHRQDDEILNQILNAIRAQSIQTEHLQALHQSRTHDIGETFTRLYTHNMDVDNINYQHLNEIDNE
GHQFNAVLDGNEKLLETLKSSVRAPEELTLKKHAKVMFVKNNFDMGYINGSLGEVIGFEEDDENGLLPKVKLTDGTTLLV
APETWSIENEAGKVIASFQQIPLRLAWAITIHKSQGMTLEAAEINLMHTFEKGQGYVALSRLKSLTGLKLLGFNEQALEL
DSLAVKADRRFQELSKEAEDNFANVDLTAQHKAFIRHCGGTLNETEISRNEKKLARGEKQNYASATLDETRALFEEGYEI
EDIAHERGLTPATIINHLARLHKEQKLDISVAHPGEEVVEEVRKIYKKLKKRQNPDHFSDDGSIKLRPIVEATSPRMGYD
QVRLALLFIE

Specific function: Unknown

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI82546872, Length=427, Percent_Identity=37.4707259953162, Blast_Score=283, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI25143421, Length=397, Percent_Identity=34.0050377833753, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17537113, Length=429, Percent_Identity=26.3403263403263, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17533663, Length=429, Percent_Identity=26.5734265734266, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17534623, Length=428, Percent_Identity=26.6355140186916, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17566502, Length=142, Percent_Identity=32.3943661971831, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321820, Length=304, Percent_Identity=37.828947368421, Blast_Score=197, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6323579, Length=334, Percent_Identity=38.622754491018, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI19920652, Length=405, Percent_Identity=37.037037037037, Blast_Score=243, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 64423; Mature: 64423

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQETALKLLKAGENVFLTGSAGAGKTYTLNQYIHYLKARKVPVAITASTGIAATHMNGM
CCHHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHHHHCCCCEEEEECCCEEEEECCCE
TIHTWAGIGIKDHLTDDDLKRMKERKYLKEHLENAQVLVIDEISMLHAKQLNLVNQVLKY
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHH
FKESDEAFGGIQVIVAGDFFQLPPVGRNGEANRDKFCFMSDAWVEAKFRVCYLTEQHRQD
HHHCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCEEEEECCEEEEEEEEEEEEHHCCCH
DEILNQILNAIRAQSIQTEHLQALHQSRTHDIGETFTRLYTHNMDVDNINYQHLNEIDNE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCC
GHQFNAVLDGNEKLLETLKSSVRAPEELTLKKHAKVMFVKNNFDMGYINGSLGEVIGFEE
CCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHCCEEEEEECCCCEEEECCCHHHHCCCCC
DDENGLLPKVKLTDGTTLLVAPETWSIENEAGKVIASFQQIPLRLAWAITIHKSQGMTLE
CCCCCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEEEEEECCCCCEEE
AAEINLMHTFEKGQGYVALSRLKSLTGLKLLGFNEQALELDSLAVKADRRFQELSKEAED
EEEEEEEEEECCCCCEEEHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
NFANVDLTAQHKAFIRHCGGTLNETEISRNEKKLARGEKQNYASATLDETRALFEEGYEI
CCCCCEEEHHHHHHHHHCCCCCCHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
EDIAHERGLTPATIINHLARLHKEQKLDISVAHPGEEVVEEVRKIYKKLKKRQNPDHFSD
HHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCC
DGSIKLRPIVEATSPRMGYDQVRLALLFIE
CCCEEEEEEEECCCCCCCHHHEEEEEEEEC
>Mature Secondary Structure
MKQETALKLLKAGENVFLTGSAGAGKTYTLNQYIHYLKARKVPVAITASTGIAATHMNGM
CCHHHHHHHHHCCCCEEEEECCCCCCEEEHHHHHHHHHHCCCCEEEEECCCEEEEECCCE
TIHTWAGIGIKDHLTDDDLKRMKERKYLKEHLENAQVLVIDEISMLHAKQLNLVNQVLKY
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHH
FKESDEAFGGIQVIVAGDFFQLPPVGRNGEANRDKFCFMSDAWVEAKFRVCYLTEQHRQD
HHHCCCCCCCEEEEEECCCEECCCCCCCCCCCCCCEEEEECCEEEEEEEEEEEEHHCCCH
DEILNQILNAIRAQSIQTEHLQALHQSRTHDIGETFTRLYTHNMDVDNINYQHLNEIDNE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCC
GHQFNAVLDGNEKLLETLKSSVRAPEELTLKKHAKVMFVKNNFDMGYINGSLGEVIGFEE
CCEEEEEECCCHHHHHHHHHHHCCCHHHHHHHCCEEEEEECCCCEEEECCCHHHHCCCCC
DDENGLLPKVKLTDGTTLLVAPETWSIENEAGKVIASFQQIPLRLAWAITIHKSQGMTLE
CCCCCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEEEEEEEECCCCCEEE
AAEINLMHTFEKGQGYVALSRLKSLTGLKLLGFNEQALELDSLAVKADRRFQELSKEAED
EEEEEEEEEECCCCCEEEHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCC
NFANVDLTAQHKAFIRHCGGTLNETEISRNEKKLARGEKQNYASATLDETRALFEEGYEI
CCCCCEEEHHHHHHHHHCCCCCCHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCH
EDIAHERGLTPATIINHLARLHKEQKLDISVAHPGEEVVEEVRKIYKKLKKRQNPDHFSD
HHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCC
DGSIKLRPIVEATSPRMGYDQVRLALLFIE
CCCEEEEEEEECCCCCCCHHHEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA