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The map label for this gene is murB [H]

Identifier: 213158422

GI number: 213158422

Start: 2454672

End: 2455706

Strand: Reverse

Name: murB [H]

Synonym: AB57_2371

Alternate gene names: 213158422

Gene position: 2455706-2454672 (Counterclockwise)

Preceding gene: 213158423

Following gene: 213158421

Centisome position: 60.63

GC content: 36.81

Gene sequence:

>1035_bases
ATGCAAATTCAAAATCAAGTACAGCTTAAGCCATTCAATACTTTAAGTTTAGATGTTACAGCTTCTCATTACACTAAGGT
CAAATCTATTGAAGATATTGAAGAAGCTTTAGCTTTTGCTAAAGAGCATGAGCTAAATGTACTTGTATTATCTGGCGGTA
GTAACATGCTATTACCGCAACAAATTAATGCTTTAGTTATTCATCTTGATATTCAGGGCATAGATGTTTTATCTGAAGAT
CAGGATTTTATTCGAGTTAAAGTCGGTGCAGGGCAGGTTTGGCACGATTTCGTTTTATACACTACAAAGCAAAATTGGTT
TGGCTTACAGAACTTGGCACTTATTCCGGGCTTGGTGGGTGCTTCACCAGTGCAAAATATTGGTGCTTATGGCGTTGAGG
TTGGTGAGTTTATTGAGTCGGTACAAGTCTATGACCGTCTATTAAAACAAACCGGATCAATTTCGGCAGCAGATTGTCAT
TTTTCTTATCGACATAGCATTTTTAAAGATGACCCAGCTCGTTACATCATTACTCACGTCACCTTTAAGCTGCTTAAACA
AGCCAATCTAAAGCTAAATTACGGTGATTTAAAACAGGCAGTAGGAGATAACCTGACTGCTGAAAATTTACAAAATCAGG
TCATTCATATTCGTCAAAGTAAATTACCTGATCCAAAAGAATATCCGAATGTAGGAAGTTTCTTTAAAAATCCGATTGTA
AATACTCAAGAATTTGAACGATTAATCGCACAATTCTCAACAATTCCGCATTATCCTCAAGCTAATGGTAACGTTAAAAT
TGCTGCTGGTTGGTTAATTGATCAGGCTGGATGGAAGGGTAAACAGCTTGGTGTAGTGGGGATGTTCCATAAGCAAGCCT
TGGTTTTGGTGAATTATGCTAATGCATCTCTTGCGGATGTAAAGAAAACTTATCAAGCTGTACAACATGATGTTGAACAG
CGTTTCCAAATTATGTTAGAACCAGAGCCTGTGCTTTATAACAATTTAGGTTTAATTGAAAATCATACGGAATAG

Upstream 100 bases:

>100_bases
GGCTTTGAACGTGTACTCGACCAATGTGAATCAAGTGCGTTGGCGTGGATTAATATCCTAAAAAAACAATTGAATGTTTA
AGAACAGGTTTTTCAATACA

Downstream 100 bases:

>100_bases
TTTTATGCCAAAAGTACACTTGATGGTACGTTTTGTACAAGTAGTTACTGTACTATTTGTACTATTAGGCTGTTTCGTGA
TTTTTTTGTATTCGCCGTTT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MQIQNQVQLKPFNTLSLDVTASHYTKVKSIEDIEEALAFAKEHELNVLVLSGGSNMLLPQQINALVIHLDIQGIDVLSED
QDFIRVKVGAGQVWHDFVLYTTKQNWFGLQNLALIPGLVGASPVQNIGAYGVEVGEFIESVQVYDRLLKQTGSISAADCH
FSYRHSIFKDDPARYIITHVTFKLLKQANLKLNYGDLKQAVGDNLTAENLQNQVIHIRQSKLPDPKEYPNVGSFFKNPIV
NTQEFERLIAQFSTIPHYPQANGNVKIAAGWLIDQAGWKGKQLGVVGMFHKQALVLVNYANASLADVKKTYQAVQHDVEQ
RFQIMLEPEPVLYNNLGLIENHTE

Sequences:

>Translated_344_residues
MQIQNQVQLKPFNTLSLDVTASHYTKVKSIEDIEEALAFAKEHELNVLVLSGGSNMLLPQQINALVIHLDIQGIDVLSED
QDFIRVKVGAGQVWHDFVLYTTKQNWFGLQNLALIPGLVGASPVQNIGAYGVEVGEFIESVQVYDRLLKQTGSISAADCH
FSYRHSIFKDDPARYIITHVTFKLLKQANLKLNYGDLKQAVGDNLTAENLQNQVIHIRQSKLPDPKEYPNVGSFFKNPIV
NTQEFERLIAQFSTIPHYPQANGNVKIAAGWLIDQAGWKGKQLGVVGMFHKQALVLVNYANASLADVKKTYQAVQHDVEQ
RFQIMLEPEPVLYNNLGLIENHTE
>Mature_344_residues
MQIQNQVQLKPFNTLSLDVTASHYTKVKSIEDIEEALAFAKEHELNVLVLSGGSNMLLPQQINALVIHLDIQGIDVLSED
QDFIRVKVGAGQVWHDFVLYTTKQNWFGLQNLALIPGLVGASPVQNIGAYGVEVGEFIESVQVYDRLLKQTGSISAADCH
FSYRHSIFKDDPARYIITHVTFKLLKQANLKLNYGDLKQAVGDNLTAENLQNQVIHIRQSKLPDPKEYPNVGSFFKNPIV
NTQEFERLIAQFSTIPHYPQANGNVKIAAGWLIDQAGWKGKQLGVVGMFHKQALVLVNYANASLADVKKTYQAVQHDVEQ
RFQIMLEPEPVLYNNLGLIENHTE

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=322, Percent_Identity=42.2360248447205, Blast_Score=247, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 38587; Mature: 38587

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIQNQVQLKPFNTLSLDVTASHYTKVKSIEDIEEALAFAKEHELNVLVLSGGSNMLLPQ
CCCCCCEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCC
QINALVIHLDIQGIDVLSEDQDFIRVKVGAGQVWHDFVLYTTKQNWFGLQNLALIPGLVG
CCCEEEEEEEECCCEEECCCCCEEEEEECCCCEEEEEEEEEECCCCCCCCHHHHHCCCCC
ASPVQNIGAYGVEVGEFIESVQVYDRLLKQTGSISAADCHFSYRHSIFKDDPARYIITHV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCCCHHHHHHHH
TFKLLKQANLKLNYGDLKQAVGDNLTAENLQNQVIHIRQSKLPDPKEYPNVGSFFKNPIV
HHHHHHHCCCEECHHHHHHHHCCCCCHHHHHHHHEEEHHHCCCCCCCCCCHHHHHHCCCC
NTQEFERLIAQFSTIPHYPQANGNVKIAAGWLIDQAGWKGKQLGVVGMFHKQALVLVNYA
CHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCEEEEECCCEEEEEEEC
NASLADVKKTYQAVQHDVEQRFQIMLEPEPVLYNNLGLIENHTE
CCHHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MQIQNQVQLKPFNTLSLDVTASHYTKVKSIEDIEEALAFAKEHELNVLVLSGGSNMLLPQ
CCCCCCEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEECCC
QINALVIHLDIQGIDVLSEDQDFIRVKVGAGQVWHDFVLYTTKQNWFGLQNLALIPGLVG
CCCEEEEEEEECCCEEECCCCCEEEEEECCCCEEEEEEEEEECCCCCCCCHHHHHCCCCC
ASPVQNIGAYGVEVGEFIESVQVYDRLLKQTGSISAADCHFSYRHSIFKDDPARYIITHV
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCCCHHHHHHHH
TFKLLKQANLKLNYGDLKQAVGDNLTAENLQNQVIHIRQSKLPDPKEYPNVGSFFKNPIV
HHHHHHHCCCEECHHHHHHHHCCCCCHHHHHHHHEEEHHHCCCCCCCCCCHHHHHHCCCC
NTQEFERLIAQFSTIPHYPQANGNVKIAAGWLIDQAGWKGKQLGVVGMFHKQALVLVNYA
CHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCEEEEECCCEEEEEEEC
NASLADVKKTYQAVQHDVEQRFQIMLEPEPVLYNNLGLIENHTE
CCHHHHHHHHHHHHHHHHHHHHEEEECCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA