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The map label for this gene is fdhA [H]

Identifier: 213158401

GI number: 213158401

Start: 2428229

End: 2430502

Strand: Reverse

Name: fdhA [H]

Synonym: AB57_2349

Alternate gene names: 213158401

Gene position: 2430502-2428229 (Counterclockwise)

Preceding gene: 213158402

Following gene: 213158400

Centisome position: 60.0

GC content: 40.06

Gene sequence:

>2274_bases
ATGATGGACGCAGCTCAGCAAAGTAAAACAGATGTGACCGCATGTATTTTATGTTCAAGAAACTGCGGTTTGAGCGTAGA
AATTAAAGATAACCAATTTGTCAAAATTAAAGGCAATCCTGAACATCCATTTTCTCAAGGTTACATTTGTCAAAAAGCTG
CCAGATTACAGCATTACCAGAAACATGCAGACCGTTTGACCGCACCTTTAAAACGCCAGCCAGATGGCTCGTTTCAAGAA
ATTAGTTGGGATGTGGCGATACAAGAAATTTCCAATCAATTGGTTCAGATTAGAGATAAATTTGGCGGCACTGCTTTTGC
TTCGGTTGGGGGCGGTGGACAGGGTAACCACCTCGGTGCAGCTTATGGCCGACAACTTTTATTGGCTATGAAAAGTTATT
ATGCATATAACTCACTTGCCCAAGAAAAAACAGGTGATTTCTGGCTCAATGGCCGCCTGTTCGGTAGTCAGGCCTGCCAT
ACTACAGAAGATGTTGAACATGCAGATTACGTACTTTTTATTGGAACGAACCCGTTTCAGGCACATGGTATTCCCAACGC
ACGAGACACGCTAAAACATATTAAGAAAGATCCGAACCGAACCATGGTGGTGTTCGACCCGCGTGTTACTGAAACGGCAA
AACAAGCAGACATTCACGTGCAGCTAAAACCGGGAACAGATACTTTTTTAATGTCGGCCATGATTGCAATCATTATTAAA
GAAAAGCTTTATGATGCAGTGTTTATTGAGCAGCATACACATGGGTTTGAAGAAGTAAAAGCTGCATTTAACCATGTCCC
GATTGAAGACTATATTGCTAAAGCTGATGTACCTGTCGATTTGATTTATCAGGTTGTTCGAGATTTTTCAAAGGCAAAAA
GAGGCTGTGTACGTATCGATTTAGGTATTCAACATACTTTGAATACAACATTAAATGGTTATTTAGAAAAGCTTTTATAC
TTACTGACAGGGAACTTTGGAAAACAGGGTACCAATAATTTGCATACCATGTTTATTCCAATTTTGACCGATACGGATGA
AAGAAAACCAAAATATCGACGTAGTGTTTATCATAAAATGTTCCCGATTTCCGGGTTTTTCCCGCCTAATATTTTACCCG
ATGAAATCCTAAAAGCAGGGGAAAAGCGAATTCGTGCTGTGTTTGTAGATAGTTGTAATCCACTATTAACTTACCCTGAT
ACACCAGCTTTTGAGGAAGCCTTTAAAGCATTAGATTTATTGGTTGTGGTTGATGTTGCCATGACAGAAACCGCGAGACT
CGCCGACTATATTTTGCCTGCTCATACTCAGTTTGAAAAATGGGAGTTTACCGGTTTTAACTTGGAATTTCCTAAGAATG
GTTTTCACCTGCGTCATCCCGTATTGGCTGCTCAAGCAAACACTTTACCGGAAGCCGAAATTTATACTCGATTACTGGAA
GCTATGAATGCTATTCCGAAGAGTTTCCCAGTTTTAGAAAAAATAGCTGCGGTCGACTCGAAAAAAACTGCCTACTTACT
ATACTTGTCGGCGTTAGGAATTACCTTGGCACGACATAAAAAATATATCCCTTTTGCTGCCTCTATTATTTATCGAACTC
TTGGCAAACGACTTGGCAATTCTGCAGATTCAGTTGCTTTTTTATTGCCGCTATCTATTCAATATGCTGTATTACATACC
AAAGCAGTACGCCGTGCAGGTTATAAAGGTAATCCGTTAACACAAGGTGTCAAACTATTTGAGCAGATATTAAAGCAACG
TTCAGGTATGGTTTTATCGCAACATGAATATGACGAAGTCTGGAAACTGCTAGCTTATAAAGATAAGAAAATACGTCTAG
CTATTCCCGAGATGTTAATTGAGCTCGCAAGCTTGAAAAGCCATAACGTTAATATAGAAGAGTTTCCTTTTATCCTCTTA
TCAGGTGAGCGACGTAGTTATAACGCCAACCAAATTTACCGTGACCCAGCATGGCGAAAAGTAGATGCTGAAGGAGCTTT
ACGAATTCATCCTGAAGATGCAGAGGCCTTAAATGTAGCTATGGGTGATCAAATCAAATGTATCTCACAACATGGAGAAA
TTCAGGTTACTGTAGATTTTGATGAGGGAATGCGAAAAGGAGTTGTTTCGCTTCCACATGGTTATGGCATGCGCTTTCAA
GGTGGAGAACCGATTGGACCACAATTAAACATGCTCATTTCTGGTGAGCATTGTGACCCTTTATCTAAAACACCTTACCA
TAAATATGTACCCATCCGTTTAGAAAAGTGCTAG

Upstream 100 bases:

>100_bases
TTTTAAATTTTGAGTTATTGACTGTTCAGAATTTAAGTTCTATTTTGGAACTTATTATTTTCATTCTAGCCAGATGTATA
AAAATAAACGGAGCCAGAAA

Downstream 100 bases:

>100_bases
AAATAAAGTAGGGCATATAAAAGGTTGACGCCGCACTGATTTTATAAAGCTTTAAAGTTTGAGCTAAAACGGTACGGCCG
AAATTTCAAATACAACCCAA

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 757; Mature: 757

Protein sequence:

>757_residues
MMDAAQQSKTDVTACILCSRNCGLSVEIKDNQFVKIKGNPEHPFSQGYICQKAARLQHYQKHADRLTAPLKRQPDGSFQE
ISWDVAIQEISNQLVQIRDKFGGTAFASVGGGGQGNHLGAAYGRQLLLAMKSYYAYNSLAQEKTGDFWLNGRLFGSQACH
TTEDVEHADYVLFIGTNPFQAHGIPNARDTLKHIKKDPNRTMVVFDPRVTETAKQADIHVQLKPGTDTFLMSAMIAIIIK
EKLYDAVFIEQHTHGFEEVKAAFNHVPIEDYIAKADVPVDLIYQVVRDFSKAKRGCVRIDLGIQHTLNTTLNGYLEKLLY
LLTGNFGKQGTNNLHTMFIPILTDTDERKPKYRRSVYHKMFPISGFFPPNILPDEILKAGEKRIRAVFVDSCNPLLTYPD
TPAFEEAFKALDLLVVVDVAMTETARLADYILPAHTQFEKWEFTGFNLEFPKNGFHLRHPVLAAQANTLPEAEIYTRLLE
AMNAIPKSFPVLEKIAAVDSKKTAYLLYLSALGITLARHKKYIPFAASIIYRTLGKRLGNSADSVAFLLPLSIQYAVLHT
KAVRRAGYKGNPLTQGVKLFEQILKQRSGMVLSQHEYDEVWKLLAYKDKKIRLAIPEMLIELASLKSHNVNIEEFPFILL
SGERRSYNANQIYRDPAWRKVDAEGALRIHPEDAEALNVAMGDQIKCISQHGEIQVTVDFDEGMRKGVVSLPHGYGMRFQ
GGEPIGPQLNMLISGEHCDPLSKTPYHKYVPIRLEKC

Sequences:

>Translated_757_residues
MMDAAQQSKTDVTACILCSRNCGLSVEIKDNQFVKIKGNPEHPFSQGYICQKAARLQHYQKHADRLTAPLKRQPDGSFQE
ISWDVAIQEISNQLVQIRDKFGGTAFASVGGGGQGNHLGAAYGRQLLLAMKSYYAYNSLAQEKTGDFWLNGRLFGSQACH
TTEDVEHADYVLFIGTNPFQAHGIPNARDTLKHIKKDPNRTMVVFDPRVTETAKQADIHVQLKPGTDTFLMSAMIAIIIK
EKLYDAVFIEQHTHGFEEVKAAFNHVPIEDYIAKADVPVDLIYQVVRDFSKAKRGCVRIDLGIQHTLNTTLNGYLEKLLY
LLTGNFGKQGTNNLHTMFIPILTDTDERKPKYRRSVYHKMFPISGFFPPNILPDEILKAGEKRIRAVFVDSCNPLLTYPD
TPAFEEAFKALDLLVVVDVAMTETARLADYILPAHTQFEKWEFTGFNLEFPKNGFHLRHPVLAAQANTLPEAEIYTRLLE
AMNAIPKSFPVLEKIAAVDSKKTAYLLYLSALGITLARHKKYIPFAASIIYRTLGKRLGNSADSVAFLLPLSIQYAVLHT
KAVRRAGYKGNPLTQGVKLFEQILKQRSGMVLSQHEYDEVWKLLAYKDKKIRLAIPEMLIELASLKSHNVNIEEFPFILL
SGERRSYNANQIYRDPAWRKVDAEGALRIHPEDAEALNVAMGDQIKCISQHGEIQVTVDFDEGMRKGVVSLPHGYGMRFQ
GGEPIGPQLNMLISGEHCDPLSKTPYHKYVPIRLEKC
>Mature_757_residues
MMDAAQQSKTDVTACILCSRNCGLSVEIKDNQFVKIKGNPEHPFSQGYICQKAARLQHYQKHADRLTAPLKRQPDGSFQE
ISWDVAIQEISNQLVQIRDKFGGTAFASVGGGGQGNHLGAAYGRQLLLAMKSYYAYNSLAQEKTGDFWLNGRLFGSQACH
TTEDVEHADYVLFIGTNPFQAHGIPNARDTLKHIKKDPNRTMVVFDPRVTETAKQADIHVQLKPGTDTFLMSAMIAIIIK
EKLYDAVFIEQHTHGFEEVKAAFNHVPIEDYIAKADVPVDLIYQVVRDFSKAKRGCVRIDLGIQHTLNTTLNGYLEKLLY
LLTGNFGKQGTNNLHTMFIPILTDTDERKPKYRRSVYHKMFPISGFFPPNILPDEILKAGEKRIRAVFVDSCNPLLTYPD
TPAFEEAFKALDLLVVVDVAMTETARLADYILPAHTQFEKWEFTGFNLEFPKNGFHLRHPVLAAQANTLPEAEIYTRLLE
AMNAIPKSFPVLEKIAAVDSKKTAYLLYLSALGITLARHKKYIPFAASIIYRTLGKRLGNSADSVAFLLPLSIQYAVLHT
KAVRRAGYKGNPLTQGVKLFEQILKQRSGMVLSQHEYDEVWKLLAYKDKKIRLAIPEMLIELASLKSHNVNIEEFPFILL
SGERRSYNANQIYRDPAWRKVDAEGALRIHPEDAEALNVAMGDQIKCISQHGEIQVTVDFDEGMRKGVVSLPHGYGMRFQ
GGEPIGPQLNMLISGEHCDPLSKTPYHKYVPIRLEKC

Specific function: Catalyzes the oxidation of formate [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868721, Length=460, Percent_Identity=25.8695652173913, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI1787870, Length=374, Percent_Identity=26.2032085561497, Blast_Score=117, Evalue=4e-27,
Organism=Escherichia coli, GI171474008, Length=481, Percent_Identity=23.9085239085239, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87081797, Length=517, Percent_Identity=23.5976789168279, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788534, Length=501, Percent_Identity=22.1556886227545, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006478
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 85194; Mature: 85194

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDAAQQSKTDVTACILCSRNCGLSVEIKDNQFVKIKGNPEHPFSQGYICQKAARLQHYQ
CCCCCHHCCCCEEEEEEEECCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
KHADRLTAPLKRQPDGSFQEISWDVAIQEISNQLVQIRDKFGGTAFASVGGGGQGNHLGA
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHH
AYGRQLLLAMKSYYAYNSLAQEKTGDFWLNGRLFGSQACHTTEDVEHADYVLFIGTNPFQ
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECEEECCCCCCCCCCCCCCCEEEEEECCCCC
AHGIPNARDTLKHIKKDPNRTMVVFDPRVTETAKQADIHVQLKPGTDTFLMSAMIAIIIK
CCCCCCHHHHHHHHHCCCCCEEEEECCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
EKLYDAVFIEQHTHGFEEVKAAFNHVPIEDYIAKADVPVDLIYQVVRDFSKAKRGCVRID
HHHHHHHEEHHHCCCHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEE
LGIQHTLNTTLNGYLEKLLYLLTGNFGKQGTNNLHTMFIPILTDTDERKPKYRRSVYHKM
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHH
FPISGFFPPNILPDEILKAGEKRIRAVFVDSCNPLLTYPDTPAFEEAFKALDLLVVVDVA
CCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
MTETARLADYILPAHTQFEKWEFTGFNLEFPKNGFHLRHPVLAAQANTLPEAEIYTRLLE
HHHHHHHHHHHCCCCCCCCCEEEECEEEECCCCCCEECCCCHHHCCCCCCHHHHHHHHHH
AMNAIPKSFPVLEKIAAVDSKKTAYLLYLSALGITLARHKKYIPFAASIIYRTLGKRLGN
HHHHCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
SADSVAFLLPLSIQYAVLHTKAVRRAGYKGNPLTQGVKLFEQILKQRSGMVLSQHEYDEV
CCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCHHHH
WKLLAYKDKKIRLAIPEMLIELASLKSHNVNIEEFPFILLSGERRSYNANQIYRDPAWRK
HHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCHHHCCEEEEECCCCCCCCCCEECCCCCEE
VDAEGALRIHPEDAEALNVAMGDQIKCISQHGEIQVTVDFDEGMRKGVVSLPHGYGMRFQ
ECCCCEEEECCCCCHHEEECCCCCEEEECCCCCEEEEEECCCCHHCCCEECCCCCCEEEC
GGEPIGPQLNMLISGEHCDPLSKTPYHKYVPIRLEKC
CCCCCCCCEEEEEECCCCCCCCCCCCCCEECEEEECC
>Mature Secondary Structure
MMDAAQQSKTDVTACILCSRNCGLSVEIKDNQFVKIKGNPEHPFSQGYICQKAARLQHYQ
CCCCCHHCCCCEEEEEEEECCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
KHADRLTAPLKRQPDGSFQEISWDVAIQEISNQLVQIRDKFGGTAFASVGGGGQGNHLGA
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHH
AYGRQLLLAMKSYYAYNSLAQEKTGDFWLNGRLFGSQACHTTEDVEHADYVLFIGTNPFQ
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECEEECCCCCCCCCCCCCCCEEEEEECCCCC
AHGIPNARDTLKHIKKDPNRTMVVFDPRVTETAKQADIHVQLKPGTDTFLMSAMIAIIIK
CCCCCCHHHHHHHHHCCCCCEEEEECCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
EKLYDAVFIEQHTHGFEEVKAAFNHVPIEDYIAKADVPVDLIYQVVRDFSKAKRGCVRID
HHHHHHHEEHHHCCCHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEE
LGIQHTLNTTLNGYLEKLLYLLTGNFGKQGTNNLHTMFIPILTDTDERKPKYRRSVYHKM
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEECCCCCCHHHHHHHHHHH
FPISGFFPPNILPDEILKAGEKRIRAVFVDSCNPLLTYPDTPAFEEAFKALDLLVVVDVA
CCCCCCCCCCCCHHHHHHHHHHHEEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHH
MTETARLADYILPAHTQFEKWEFTGFNLEFPKNGFHLRHPVLAAQANTLPEAEIYTRLLE
HHHHHHHHHHHCCCCCCCCCEEEECEEEECCCCCCEECCCCHHHCCCCCCHHHHHHHHHH
AMNAIPKSFPVLEKIAAVDSKKTAYLLYLSALGITLARHKKYIPFAASIIYRTLGKRLGN
HHHHCCCCCHHHHHHHHCCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
SADSVAFLLPLSIQYAVLHTKAVRRAGYKGNPLTQGVKLFEQILKQRSGMVLSQHEYDEV
CCCCEEEEEECHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCEEECCCHHHH
WKLLAYKDKKIRLAIPEMLIELASLKSHNVNIEEFPFILLSGERRSYNANQIYRDPAWRK
HHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCHHHCCEEEEECCCCCCCCCCEECCCCCEE
VDAEGALRIHPEDAEALNVAMGDQIKCISQHGEIQVTVDFDEGMRKGVVSLPHGYGMRFQ
ECCCCEEEECCCCCHHEEECCCCCEEEECCCCCEEEEEECCCCHHCCCEECCCCCCEEEC
GGEPIGPQLNMLISGEHCDPLSKTPYHKYVPIRLEKC
CCCCCCCCEEEEEECCCCCCCCCCCCCCEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]