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The map label for this gene is galE [H]

Identifier: 213158387

GI number: 213158387

Start: 2418485

End: 2419492

Strand: Reverse

Name: galE [H]

Synonym: AB57_2335

Alternate gene names: 213158387

Gene position: 2419492-2418485 (Counterclockwise)

Preceding gene: 213158392

Following gene: 213158386

Centisome position: 59.73

GC content: 37.3

Gene sequence:

>1008_bases
ATGATTTTAGTGACAGGTGGTTTAGGCTTTATCGGTTCACATATTGCATTGAGTCTCATGGCTCAAGGCCAAGAAGTGGT
TCTTGTCGATAATTTGGCTAACTCGACCTTGCAAACGCTTGAGCGGTTAGAATACATCTCTGGTATGTACGTTCCGTTTG
TTAAACTTGATGTACGTAACACGCCTGCATTGAACAAAGTATTTGAACAGTACTCAATTGATGCAGTCATTCATACGGCT
GGTTTTAAATCTATTGAAGAGTCTAATTTAAAACCGCTTGAATATTATAATGATAATGTCAGTTGTATCATGAGCCTATT
GCGTGCAATGCAACGTACAGGCGTCCGTCATTTTATTCATTTATCTAGTTTGGCAGTCTATGGAAAATCTGGTTCACAGT
TAAGCGAAACAGATGATTTCAACTATGCTTATCCTAACCCTTATATTAAGTCGCAACAGATGATTGAAGAAATCATCCGT
GATACTTACAAAATTGATCATGAATGGAAAATTGCAATTTTACGTCTATCAAATATTGTAGGTGCTTTTGAGCATGGCGT
ATTAGGCGAGTATGTAGCACAGCTCCCTAAAAATATTGTACCGCTTGCCATGCAAGTTGCAGCGATGCAACGTGATTTAA
TTGAGTTACAGGATCAGTCTTCTACCGAAGACCATACCGTAGAACGTAGCTTTTTACATGTATTAGATGTATGTGAGGCA
GTAAGCTCAACTTTACATTGGTTACGTGATCAAAGCCATTGCTGTGAAGCTTTTAATATTGCTCATGAGCAAGTGCATTC
GATTCGTCAATTATTAGATGAAATTTCACAGGTTACCCAAGCCGAAATTCCGACACAATCTGCGATTTATAAGCATGAAG
AGTTAGCGCAGATTGGTGCAAATATAGGAAAAGCAAAAACTTTATTACAATGGGTACCGAAGCGAACTTTAAAACAAATG
ATTGAAGATGAATGGAGATTTTATCAAAATACATTAAATGGAAGATAA

Upstream 100 bases:

>100_bases
GTAGGAGCAGAGGTTATTAGTAGTAATGTACTCATTGAGAATTCACTATGGTCATACGTCTAAATGGGCGTAGATACATT
AAGAGAAAGGTAAGTATACA

Downstream 100 bases:

>100_bases
GATAATGATTCTTATTTACAATAATGGAATGCTTGAGTACGATACTAAAATTAACTAGCCAAAGCATAAATTGCTTCAGC
CCGTGAGTTCTTTAACCAGA

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MILVTGGLGFIGSHIALSLMAQGQEVVLVDNLANSTLQTLERLEYISGMYVPFVKLDVRNTPALNKVFEQYSIDAVIHTA
GFKSIEESNLKPLEYYNDNVSCIMSLLRAMQRTGVRHFIHLSSLAVYGKSGSQLSETDDFNYAYPNPYIKSQQMIEEIIR
DTYKIDHEWKIAILRLSNIVGAFEHGVLGEYVAQLPKNIVPLAMQVAAMQRDLIELQDQSSTEDHTVERSFLHVLDVCEA
VSSTLHWLRDQSHCCEAFNIAHEQVHSIRQLLDEISQVTQAEIPTQSAIYKHEELAQIGANIGKAKTLLQWVPKRTLKQM
IEDEWRFYQNTLNGR

Sequences:

>Translated_335_residues
MILVTGGLGFIGSHIALSLMAQGQEVVLVDNLANSTLQTLERLEYISGMYVPFVKLDVRNTPALNKVFEQYSIDAVIHTA
GFKSIEESNLKPLEYYNDNVSCIMSLLRAMQRTGVRHFIHLSSLAVYGKSGSQLSETDDFNYAYPNPYIKSQQMIEEIIR
DTYKIDHEWKIAILRLSNIVGAFEHGVLGEYVAQLPKNIVPLAMQVAAMQRDLIELQDQSSTEDHTVERSFLHVLDVCEA
VSSTLHWLRDQSHCCEAFNIAHEQVHSIRQLLDEISQVTQAEIPTQSAIYKHEELAQIGANIGKAKTLLQWVPKRTLKQM
IEDEWRFYQNTLNGR
>Mature_335_residues
MILVTGGLGFIGSHIALSLMAQGQEVVLVDNLANSTLQTLERLEYISGMYVPFVKLDVRNTPALNKVFEQYSIDAVIHTA
GFKSIEESNLKPLEYYNDNVSCIMSLLRAMQRTGVRHFIHLSSLAVYGKSGSQLSETDDFNYAYPNPYIKSQQMIEEIIR
DTYKIDHEWKIAILRLSNIVGAFEHGVLGEYVAQLPKNIVPLAMQVAAMQRDLIELQDQSSTEDHTVERSFLHVLDVCEA
VSSTLHWLRDQSHCCEAFNIAHEQVHSIRQLLDEISQVTQAEIPTQSAIYKHEELAQIGANIGKAKTLLQWVPKRTLKQM
IEDEWRFYQNTLNGR

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=345, Percent_Identity=33.6231884057971, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI56118217, Length=345, Percent_Identity=33.6231884057971, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI189083684, Length=345, Percent_Identity=33.6231884057971, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI7657641, Length=281, Percent_Identity=27.0462633451957, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786974, Length=328, Percent_Identity=34.1463414634146, Blast_Score=199, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI71982035, Length=335, Percent_Identity=31.3432835820896, Blast_Score=189, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI71982038, Length=337, Percent_Identity=31.4540059347181, Blast_Score=189, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI17568069, Length=250, Percent_Identity=24.8, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115532424, Length=332, Percent_Identity=25.6024096385542, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=335, Percent_Identity=31.044776119403, Blast_Score=188, Evalue=8e-49,
Organism=Drosophila melanogaster, GI19923002, Length=341, Percent_Identity=30.2052785923754, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38051; Mature: 38051

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVTGGLGFIGSHIALSLMAQGQEVVLVDNLANSTLQTLERLEYISGMYVPFVKLDVRN
CEEEECCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
TPALNKVFEQYSIDAVIHTAGFKSIEESNLKPLEYYNDNVSCIMSLLRAMQRTGVRHFIH
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHHH
LSSLAVYGKSGSQLSETDDFNYAYPNPYIKSQQMIEEIIRDTYKIDHEWKIAILRLSNIV
HHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GAFEHGVLGEYVAQLPKNIVPLAMQVAAMQRDLIELQDQSSTEDHTVERSFLHVLDVCEA
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VSSTLHWLRDQSHCCEAFNIAHEQVHSIRQLLDEISQVTQAEIPTQSAIYKHEELAQIGA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
NIGKAKTLLQWVPKRTLKQMIEDEWRFYQNTLNGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MILVTGGLGFIGSHIALSLMAQGQEVVLVDNLANSTLQTLERLEYISGMYVPFVKLDVRN
CEEEECCHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
TPALNKVFEQYSIDAVIHTAGFKSIEESNLKPLEYYNDNVSCIMSLLRAMQRTGVRHFIH
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHCCCCHHHHHHHHHHHHHCCHHHHHH
LSSLAVYGKSGSQLSETDDFNYAYPNPYIKSQQMIEEIIRDTYKIDHEWKIAILRLSNIV
HHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
GAFEHGVLGEYVAQLPKNIVPLAMQVAAMQRDLIELQDQSSTEDHTVERSFLHVLDVCEA
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VSSTLHWLRDQSHCCEAFNIAHEQVHSIRQLLDEISQVTQAEIPTQSAIYKHEELAQIGA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
NIGKAKTLLQWVPKRTLKQMIEDEWRFYQNTLNGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]