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The map label for this gene is pyrH [H]

Identifier: 213158374

GI number: 213158374

Start: 2404435

End: 2405163

Strand: Reverse

Name: pyrH [H]

Synonym: AB57_2320

Alternate gene names: 213158374

Gene position: 2405163-2404435 (Counterclockwise)

Preceding gene: 213158375

Following gene: 213158373

Centisome position: 59.38

GC content: 40.19

Gene sequence:

>729_bases
ATGGCGGAAACAATCAGCCCCCGTTATTCACGAATTTTATTAAAATTATCTGGTGAAGCTTTATCAGGTAATAAAGATAT
GGGTATTGATGCTCAAGTTTTAGATCAGATGTCACTTTCTATTGCACATTTGGTTGGCTTGGGTGTGCAAGTAGGTATCG
TTGTGGGTGGCGGTAACTTATATCGTGGTAGCCAGTTACAAAAAGACGGTTTGGTTGGCCGTGTAACAGGTGATCAGATG
GGGATGCTTGCAACTGTTATGAATGGTTTGGCAATGCGTGATGCATTGGTGCGCCGTAATATCAGAACTCGTCTTATGTC
AGCGCTACCAATCGGTACTGTTGTAGAGTCTTACTCAAGTCGTGATGCGATTCGTCATTTAAGCCAAGGCGAAGTGTGTG
TTTTTGTAGCAGGGACAGGAAATCCATTCTTTACAACTGATACAGCAGCATGTTTACGTGGTATTGAAATTGAAGCAAAT
TTAATTTTGAAAGCGACCAAAGTAGACGGTGTTTATAATAAAGATCCGAGCAAATACGAAGATGCAGTGAAATATGACCA
TTTAACATTTGACCAAGTGTTAGATGAAAAACTGGGTGTTATGGATTTAACGGCAATTTGCTTATGCCGTGACCATAATG
TTCCATTGCAAGTATTTGATATGAATAAATCTGGTGCGCTATTGTCAGTGGTAATGGGTGAAAAAGAGGGTACACGCGTT
ACTAAATAA

Upstream 100 bases:

>100_bases
GGATGAATACGACTTATTTGCAAAGTTAATTAAAATTAAATCGGTCTAATCGAATCACGATTCAAAAAGCATTCAGTTTA
AGAGGTCTTGGAGCAAAATC

Downstream 100 bases:

>100_bases
TGTACGTGTGCCGTAAAGCTCTTTATACTAGCGCTAAATTAAATTTGTTATATACATCCTTGAATAAATAAGTAAGGAAG
ATCATATGATTAACGATCTG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MAETISPRYSRILLKLSGEALSGNKDMGIDAQVLDQMSLSIAHLVGLGVQVGIVVGGGNLYRGSQLQKDGLVGRVTGDQM
GMLATVMNGLAMRDALVRRNIRTRLMSALPIGTVVESYSSRDAIRHLSQGEVCVFVAGTGNPFFTTDTAACLRGIEIEAN
LILKATKVDGVYNKDPSKYEDAVKYDHLTFDQVLDEKLGVMDLTAICLCRDHNVPLQVFDMNKSGALLSVVMGEKEGTRV
TK

Sequences:

>Translated_242_residues
MAETISPRYSRILLKLSGEALSGNKDMGIDAQVLDQMSLSIAHLVGLGVQVGIVVGGGNLYRGSQLQKDGLVGRVTGDQM
GMLATVMNGLAMRDALVRRNIRTRLMSALPIGTVVESYSSRDAIRHLSQGEVCVFVAGTGNPFFTTDTAACLRGIEIEAN
LILKATKVDGVYNKDPSKYEDAVKYDHLTFDQVLDEKLGVMDLTAICLCRDHNVPLQVFDMNKSGALLSVVMGEKEGTRV
TK
>Mature_241_residues
AETISPRYSRILLKLSGEALSGNKDMGIDAQVLDQMSLSIAHLVGLGVQVGIVVGGGNLYRGSQLQKDGLVGRVTGDQMG
MLATVMNGLAMRDALVRRNIRTRLMSALPIGTVVESYSSRDAIRHLSQGEVCVFVAGTGNPFFTTDTAACLRGIEIEANL
ILKATKVDGVYNKDPSKYEDAVKYDHLTFDQVLDEKLGVMDLTAICLCRDHNVPLQVFDMNKSGALLSVVMGEKEGTRVT
K

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=242, Percent_Identity=60.7438016528926, Blast_Score=297, Evalue=4e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 26137; Mature: 26005

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETISPRYSRILLKLSGEALSGNKDMGIDAQVLDQMSLSIAHLVGLGVQVGIVVGGGNL
CCCCCCCHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCC
YRGSQLQKDGLVGRVTGDQMGMLATVMNGLAMRDALVRRNIRTRLMSALPIGTVVESYSS
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCH
RDAIRHLSQGEVCVFVAGTGNPFFTTDTAACLRGIEIEANLILKATKVDGVYNKDPSKYE
HHHHHHCCCCCEEEEEEECCCCEEECCHHHHHHCCEEEEEEEEEEEEECCCCCCCCHHHH
DAVKYDHLTFDQVLDEKLGVMDLTAICLCRDHNVPLQVFDMNKSGALLSVVMGEKEGTRV
HHHHHCCCCHHHHHHHHCCHHHHEEEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCC
TK
CC
>Mature Secondary Structure 
AETISPRYSRILLKLSGEALSGNKDMGIDAQVLDQMSLSIAHLVGLGVQVGIVVGGGNL
CCCCCCHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEEEEECCCC
YRGSQLQKDGLVGRVTGDQMGMLATVMNGLAMRDALVRRNIRTRLMSALPIGTVVESYSS
CCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCH
RDAIRHLSQGEVCVFVAGTGNPFFTTDTAACLRGIEIEANLILKATKVDGVYNKDPSKYE
HHHHHHCCCCCEEEEEEECCCCEEECCHHHHHHCCEEEEEEEEEEEEECCCCCCCCHHHH
DAVKYDHLTFDQVLDEKLGVMDLTAICLCRDHNVPLQVFDMNKSGALLSVVMGEKEGTRV
HHHHHCCCCHHHHHHHHCCHHHHEEEEEEECCCCCEEEEECCCCCCEEEEEECCCCCCCC
TK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA