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The map label for this gene is frr [H]

Identifier: 213158373

GI number: 213158373

Start: 2403795

End: 2404349

Strand: Reverse

Name: frr [H]

Synonym: AB57_2319

Alternate gene names: 213158373

Gene position: 2404349-2403795 (Counterclockwise)

Preceding gene: 213158374

Following gene: 213158372

Centisome position: 59.36

GC content: 39.46

Gene sequence:

>555_bases
ATGATTAACGATCTGAAAAAAGACAGCGAACAGCGTATGTTAAAAACTCTTGAGTCTTTGGAACAAGGGTTTGCTAAAGT
TCGTACCGGCCGTGCACACCCATCAATTTTAAATGGGGTAATGGTTCCTTACTATGGTTCTGATGTGCCTTTAAACCAAG
TAGCGAACGTTGGTGTTGAAGATTCTCGTACGCTTATCGTTCAACCATTTGAACGTACGATGGTTGCTGCAATTGATAAA
GCAATTCGTGAAAGTGATTTAGGTTTAAATCCTATTACTGCTGATTCAATCCGTGTACCTTTACCAGCTTTAACTGAAGA
AACACGTCGTGATATGCAGAAAATCGCTCGCAGTGAAGCTGAAAATGCGAAAGTTGCTATCCGTAATATTCGTCGTGATG
TATTAGGTGATATCAAGGCATTGTTAAAAGAGAAAGAAATTTCTGAAGATGATGAGCGTCGTGCAGGCGATGATATCCAA
AAAATCACTGATAAATATGTTGCAGAAGTAGACAAACGTCTAGCAGCGAAAGAAGCAGAATTGATGAAGGTCTAA

Upstream 100 bases:

>100_bases
CGCGTTACTAAATAATGTACGTGTGCCGTAAAGCTCTTTATACTAGCGCTAAATTAAATTTGTTATATACATCCTTGAAT
AAATAAGTAAGGAAGATCAT

Downstream 100 bases:

>100_bases
TTTTTATGACCGATTCAGAAGAGTATCATCTTCCTCAGCATGTTGCCATCATCATGGATGGCAACAATCGCTTTGCAAAG
AAAAATCAAATGCAAAAAGG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MINDLKKDSEQRMLKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGVEDSRTLIVQPFERTMVAAIDK
AIRESDLGLNPITADSIRVPLPALTEETRRDMQKIARSEAENAKVAIRNIRRDVLGDIKALLKEKEISEDDERRAGDDIQ
KITDKYVAEVDKRLAAKEAELMKV

Sequences:

>Translated_184_residues
MINDLKKDSEQRMLKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGVEDSRTLIVQPFERTMVAAIDK
AIRESDLGLNPITADSIRVPLPALTEETRRDMQKIARSEAENAKVAIRNIRRDVLGDIKALLKEKEISEDDERRAGDDIQ
KITDKYVAEVDKRLAAKEAELMKV
>Mature_184_residues
MINDLKKDSEQRMLKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGVEDSRTLIVQPFERTMVAAIDK
AIRESDLGLNPITADSIRVPLPALTEETRRDMQKIARSEAENAKVAIRNIRRDVLGDIKALLKEKEISEDDERRAGDDIQ
KITDKYVAEVDKRLAAKEAELMKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=32.9545454545455, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI291042689, Length=136, Percent_Identity=36.0294117647059, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=57.6086956521739, Blast_Score=212, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=27.0114942528736, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20642; Mature: 20642

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDLKKDSEQRMLKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHHHCCCCC
DSRTLIVQPFERTMVAAIDKAIRESDLGLNPITADSIRVPLPALTEETRRDMQKIARSEA
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ENAKVAIRNIRRDVLGDIKALLKEKEISEDDERRAGDDIQKITDKYVAEVDKRLAAKEAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LMKV
HHCC
>Mature Secondary Structure
MINDLKKDSEQRMLKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHHHCCCCC
DSRTLIVQPFERTMVAAIDKAIRESDLGLNPITADSIRVPLPALTEETRRDMQKIARSEA
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ENAKVAIRNIRRDVLGDIKALLKEKEISEDDERRAGDDIQKITDKYVAEVDKRLAAKEAE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LMKV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA