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The map label for this gene is drgA [H]

Identifier: 213158330

GI number: 213158330

Start: 3153612

End: 3154217

Strand: Direct

Name: drgA [H]

Synonym: AB57_3060

Alternate gene names: 213158330

Gene position: 3153612-3154217 (Clockwise)

Preceding gene: 213158329

Following gene: 213158332

Centisome position: 77.86

GC content: 42.57

Gene sequence:

>606_bases
ATGAATGTTATTGATGCTCTCCGCAAACGCCGTGCAGTTAAACGCTTCGACCCTGCTTTTCAACTCTCTGAAGATAACAA
AAAGCAGTTATTACAAGAAGTTTTAGCAAATGCACCAAGCGCTTTTAACTTGCAGCATTGGCGTCCAGTCATTGTTGAAG
ATGCAGAGTTAAGACAAAAAATTCGCGTGATTGCTTGGGACCAACCACAAGTAACAGAGTCATCATTACTGATTGTGTTA
TGTGCCAAAGTAAATACATGGGAAGTTGACGCTAAACGTGTATGGGATGGAGCTTCTCCAGAAGTTCAAGATATTATGGT
TGGTGCAATCGACCAGTATTACCGTGACCGCCCACAAACCCAACGTGACGAAGTGATGCGTAGTGCGGGCATCTTTGCTC
AAACCCTTATGTTACTTGCTCAAGAGCATGGTTTAGATAGCTGTCCAATGGACGGTTTTGACTTTGATGCAATGGCAAAG
CTCATTAACTTACCTGAAGACCATGTGGTGTGTTTAATGATTGCGGTTGGTAAATCAGCTTCTGAACCTTACCCGCGCGT
AGGCAAACTCCCTTACGATGATGTCATTATTAAAAATACATTCTAA

Upstream 100 bases:

>100_bases
TCGCGTATGACATTATTACCAAACTTCTCTTCGGCTGAAGTAGCCCAACGTTATAAAAACTAACGACTACGGCTACCCAA
CTCTCAAGTAGGAAAATCTT

Downstream 100 bases:

>100_bases
GTTGTAATTCAAATTTTAGGCTTTCATTCTATTTTTGTTTTTATACTAAATAGATGGAAGCCTTTAATTTTGCATTAATT
ATAAAGCTGACTTTGACTCG

Product: nitroreductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MNVIDALRKRRAVKRFDPAFQLSEDNKKQLLQEVLANAPSAFNLQHWRPVIVEDAELRQKIRVIAWDQPQVTESSLLIVL
CAKVNTWEVDAKRVWDGASPEVQDIMVGAIDQYYRDRPQTQRDEVMRSAGIFAQTLMLLAQEHGLDSCPMDGFDFDAMAK
LINLPEDHVVCLMIAVGKSASEPYPRVGKLPYDDVIIKNTF

Sequences:

>Translated_201_residues
MNVIDALRKRRAVKRFDPAFQLSEDNKKQLLQEVLANAPSAFNLQHWRPVIVEDAELRQKIRVIAWDQPQVTESSLLIVL
CAKVNTWEVDAKRVWDGASPEVQDIMVGAIDQYYRDRPQTQRDEVMRSAGIFAQTLMLLAQEHGLDSCPMDGFDFDAMAK
LINLPEDHVVCLMIAVGKSASEPYPRVGKLPYDDVIIKNTF
>Mature_201_residues
MNVIDALRKRRAVKRFDPAFQLSEDNKKQLLQEVLANAPSAFNLQHWRPVIVEDAELRQKIRVIAWDQPQVTESSLLIVL
CAKVNTWEVDAKRVWDGASPEVQDIMVGAIDQYYRDRPQTQRDEVMRSAGIFAQTLMLLAQEHGLDSCPMDGFDFDAMAK
LINLPEDHVVCLMIAVGKSASEPYPRVGKLPYDDVIIKNTF

Specific function: Controls resistance to the herbicide Dinoseb and metronidazole. Involved in detoxification of Dinoseb via the reduction of the nitro group(s) and this process is accompanied by the formation of toxic superoxide anions [H]

COG id: COG0778

COG function: function code C; Nitroreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitroreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000415 [H]

Pfam domain/function: PF00881 Nitroreductase [H]

EC number: NA

Molecular weight: Translated: 22868; Mature: 22868

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIDALRKRRAVKRFDPAFQLSEDNKKQLLQEVLANAPSAFNLQHWRPVIVEDAELRQK
CCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHH
IRVIAWDQPQVTESSLLIVLCAKVNTWEVDAKRVWDGASPEVQDIMVGAIDQYYRDRPQT
EEEEECCCCCCCCCCEEEEEECCCCCEECCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
QRDEVMRSAGIFAQTLMLLAQEHGLDSCPMDGFDFDAMAKLINLPEDHVVCLMIAVGKSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCC
SEPYPRVGKLPYDDVIIKNTF
CCCCCCCCCCCCCCEEEECCC
>Mature Secondary Structure
MNVIDALRKRRAVKRFDPAFQLSEDNKKQLLQEVLANAPSAFNLQHWRPVIVEDAELRQK
CCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHH
IRVIAWDQPQVTESSLLIVLCAKVNTWEVDAKRVWDGASPEVQDIMVGAIDQYYRDRPQT
EEEEECCCCCCCCCCEEEEEECCCCCEECCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCC
QRDEVMRSAGIFAQTLMLLAQEHGLDSCPMDGFDFDAMAKLINLPEDHVVCLMIAVGKSA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEECCCC
SEPYPRVGKLPYDDVIIKNTF
CCCCCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9654132; 8905231; 9298645 [H]