BacMap

Definition	Acinetobacter baumannii AB0057, complete genome.
Accession	NC_011586
Length	4,050,513

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The map label for this gene is sdh [H]

Identifier: 213158329

GI number: 213158329

Start: 3152792

End: 3153574

Strand: Direct

Name: sdh [H]

Synonym: AB57_3059

Alternate gene names: 213158329

Gene position: 3152792-3153574 (Clockwise)

Preceding gene: 213158327

Following gene: 213158330

Centisome position: 77.84

GC content: 38.19

Gene sequence:

>783_bases
ATGTCAGTTCAATCAAAAGTACTTATTACAGGGGCTTCGTCAGGAATTGGTTCTGTTTATGCAGATCGATTTGCTCAACG
TGGCTATCACTTAATCTTGGTGGCACGAGATACCAACCGTTTAGATAAAATTTCAAAAGATCTTCAAGAAAAATACGGCG
TACAGGTCGAGTTCATTCAAGCCGATTTATCAAACGATCAAGACATTCGCAAAATTGAAGATGTACTCAAAAACGATGCT
GATATTGAAATTTTGGTAAATAACGCTGGAATTGCTCTGAACGGAAACTTTTTAACTCAAGATCGTAATGAGATTGAAAA
ACTTCTGACTTTAAATATGACTGCGGTGGTGCGATTGTCTCATGCAATGTCGCAATCCCTTATACGCAAAGGTAAAGGTG
CCATTATTAATTTAGGCTCTGTGCTGGGCTTAGCGCCTGAATTTGGTTCTACCATTTATGGCGCAAGTAAATCTTTCATC
CAATTTTTTAGCCAAGGCTTACATTTAGAGTTAAAAGATCATGGGGTACACGTTCAAGCGGTATTGCCTTCTGCCACTAA
AACCGAAATTTGGGAACGTTCAGGTATAGATTTAAGCCAAGTTCCGCCATTAATGGATGTCAATGATTTGGTCGATGCAG
CCCTGATTGGTTTTGATCGTAAAGAAACAATTACAATTCCTGTGCTGAAAGATGAAAATCAATGGAATAATTTTGAACAA
TCGCGTATGACATTATTACCAAACTTCTCTTCGGCTGAAGTAGCCCAACGTTATAAAAACTAA

Upstream 100 bases:

>100_bases
ACCCTGCTCGTCATTATTATACATTGATTATGATTGACATCAAAACTTGTATATTTTAGATTATTATCATCATCTAAAAA
TCAAAGCGTGGAGACATCAC

Downstream 100 bases:

>100_bases
CGACTACGGCTACCCAACTCTCAAGTAGGAAAATCTTATGAATGTTATTGATGCTCTCCGCAAACGCCGTGCAGTTAAAC
GCTTCGACCCTGCTTTTCAA

Product: oxidoreductase short chain dehydrogenase/reductase family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSVQSKVLITGASSGIGSVYADRFAQRGYHLILVARDTNRLDKISKDLQEKYGVQVEFIQADLSNDQDIRKIEDVLKNDA
DIEILVNNAGIALNGNFLTQDRNEIEKLLTLNMTAVVRLSHAMSQSLIRKGKGAIINLGSVLGLAPEFGSTIYGASKSFI
QFFSQGLHLELKDHGVHVQAVLPSATKTEIWERSGIDLSQVPPLMDVNDLVDAALIGFDRKETITIPVLKDENQWNNFEQ
SRMTLLPNFSSAEVAQRYKN

Sequences:

>Translated_260_residues
MSVQSKVLITGASSGIGSVYADRFAQRGYHLILVARDTNRLDKISKDLQEKYGVQVEFIQADLSNDQDIRKIEDVLKNDA
DIEILVNNAGIALNGNFLTQDRNEIEKLLTLNMTAVVRLSHAMSQSLIRKGKGAIINLGSVLGLAPEFGSTIYGASKSFI
QFFSQGLHLELKDHGVHVQAVLPSATKTEIWERSGIDLSQVPPLMDVNDLVDAALIGFDRKETITIPVLKDENQWNNFEQ
SRMTLLPNFSSAEVAQRYKN
>Mature_259_residues
SVQSKVLITGASSGIGSVYADRFAQRGYHLILVARDTNRLDKISKDLQEKYGVQVEFIQADLSNDQDIRKIEDVLKNDAD
IEILVNNAGIALNGNFLTQDRNEIEKLLTLNMTAVVRLSHAMSQSLIRKGKGAIINLGSVLGLAPEFGSTIYGASKSFIQ
FFSQGLHLELKDHGVHVQAVLPSATKTEIWERSGIDLSQVPPLMDVNDLVDAALIGFDRKETITIPVLKDENQWNNFEQS
RMTLLPNFSSAEVAQRYKN

Specific function: Catalyzes the oxidation of the hydroxyl group of serine to form 2-aminomalonate semialdehyde which is spontaneously converted into 2-aminoacetaldehyde and CO(2). Also acts on D- serine, L-glycerate, D-glycerate and 2-methyl-DL-serine. Does not act on O-me

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=187, Percent_Identity=34.2245989304813, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI226371731, Length=188, Percent_Identity=30.8510638297872, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI4557649, Length=186, Percent_Identity=33.8709677419355, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI4503817, Length=192, Percent_Identity=30.7291666666667, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI7705925, Length=186, Percent_Identity=27.4193548387097, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI40807363, Length=218, Percent_Identity=28.8990825688073, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI20149619, Length=191, Percent_Identity=27.7486910994764, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI7706318, Length=195, Percent_Identity=29.7435897435897, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI7657478, Length=186, Percent_Identity=27.4193548387097, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI40254992, Length=185, Percent_Identity=27.5675675675676, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=32.3383084577114, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI109715829, Length=190, Percent_Identity=25.7894736842105, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI210032110, Length=234, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI32483357, Length=183, Percent_Identity=25.6830601092896, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI15277342, Length=197, Percent_Identity=28.4263959390863, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI225579078, Length=205, Percent_Identity=27.8048780487805, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI33667109, Length=186, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI5031737, Length=186, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI150247226, Length=213, Percent_Identity=28.169014084507, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=32.2222222222222, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787335, Length=211, Percent_Identity=31.2796208530806, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1790717, Length=188, Percent_Identity=28.1914893617021, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788459, Length=198, Percent_Identity=29.2929292929293, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082160, Length=186, Percent_Identity=27.4193548387097, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786701, Length=188, Percent_Identity=27.1276595744681, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI87082100, Length=187, Percent_Identity=28.8770053475936, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI2367365, Length=184, Percent_Identity=29.3478260869565, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367175, Length=198, Percent_Identity=30.8080808080808, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=194, Percent_Identity=33.5051546391753, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI212646214, Length=193, Percent_Identity=29.0155440414508, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17559552, Length=193, Percent_Identity=27.979274611399, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17560220, Length=208, Percent_Identity=35.0961538461538, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17557668, Length=193, Percent_Identity=27.979274611399, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=195, Percent_Identity=31.2820512820513, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560176, Length=190, Percent_Identity=27.8947368421053, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25152911, Length=193, Percent_Identity=29.0155440414508, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193204405, Length=207, Percent_Identity=34.7826086956522, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=208, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=197, Percent_Identity=30.9644670050761, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=200, Percent_Identity=30, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=187, Percent_Identity=26.2032085561497, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=202, Percent_Identity=30.1980198019802, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562990, Length=189, Percent_Identity=31.7460317460317, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=208, Percent_Identity=31.7307692307692, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=214, Percent_Identity=26.6355140186916, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=187, Percent_Identity=33.1550802139037, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=187, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17564282, Length=212, Percent_Identity=26.4150943396226, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=231, Percent_Identity=24.6753246753247, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=214, Percent_Identity=27.5700934579439, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=214, Percent_Identity=27.5700934579439, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=196, Percent_Identity=30.1020408163265, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=185, Percent_Identity=25.9459459459459, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6319635, Length=187, Percent_Identity=29.9465240641711, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323882, Length=237, Percent_Identity=31.2236286919831, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6322067, Length=191, Percent_Identity=30.3664921465969, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=206, Percent_Identity=26.2135922330097, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28574402, Length=188, Percent_Identity=35.1063829787234, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24584744, Length=188, Percent_Identity=35.1063829787234, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI161076933, Length=185, Percent_Identity=34.5945945945946, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24584748, Length=185, Percent_Identity=34.5945945945946, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI23397609, Length=197, Percent_Identity=37.0558375634518, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24584752, Length=186, Percent_Identity=34.4086021505376, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24640442, Length=188, Percent_Identity=28.7234042553192, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI28571526, Length=192, Percent_Identity=32.2916666666667, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357041, Length=192, Percent_Identity=31.25, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21358495, Length=190, Percent_Identity=31.0526315789474, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI116007236, Length=194, Percent_Identity=26.8041237113402, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24651139, Length=192, Percent_Identity=30.7291666666667, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007238, Length=187, Percent_Identity=25.668449197861, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24649181, Length=230, Percent_Identity=25.6521739130435, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356301, Length=198, Percent_Identity=25.2525252525253, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24643142, Length=216, Percent_Identity=28.2407407407407, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24580925, Length=189, Percent_Identity=31.2169312169312, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI281364892, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.276 [H]

Molecular weight: Translated: 28829; Mature: 28698

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVQSKVLITGASSGIGSVYADRFAQRGYHLILVARDTNRLDKISKDLQEKYGVQVEFIQ
CCCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEEEE
ADLSNDQDIRKIEDVLKNDADIEILVNNAGIALNGNFLTQDRNEIEKLLTLNMTAVVRLS
ECCCCCHHHHHHHHHHCCCCCEEEEEECCCEEEECCEECCCHHHHHHHHHCCHHHHHHHH
HAMSQSLIRKGKGAIINLGSVLGLAPEFGSTIYGASKSFIQFFSQGLHLELKDHGVHVQA
HHHHHHHHHCCCCCEEECCHHHHCCCHHCCHHHCCHHHHHHHHHCCCEEEEECCCEEEEE
VLPSATKTEIWERSGIDLSQVPPLMDVNDLVDAALIGFDRKETITIPVLKDENQWNNFEQ
ECCCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHH
SRMTLLPNFSSAEVAQRYKN
HHEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
SVQSKVLITGASSGIGSVYADRFAQRGYHLILVARDTNRLDKISKDLQEKYGVQVEFIQ
CCCCEEEEEECCCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCEEEEEE
ADLSNDQDIRKIEDVLKNDADIEILVNNAGIALNGNFLTQDRNEIEKLLTLNMTAVVRLS
ECCCCCHHHHHHHHHHCCCCCEEEEEECCCEEEECCEECCCHHHHHHHHHCCHHHHHHHH
HAMSQSLIRKGKGAIINLGSVLGLAPEFGSTIYGASKSFIQFFSQGLHLELKDHGVHVQA
HHHHHHHHHCCCCCEEECCHHHHCCCHHCCHHHCCHHHHHHHHHCCCEEEEECCCEEEEE
VLPSATKTEIWERSGIDLSQVPPLMDVNDLVDAALIGFDRKETITIPVLKDENQWNNFEQ
ECCCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCHHH
SRMTLLPNFSSAEVAQRYKN
HHEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]