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The map label for this gene is htrB [C]

Identifier: 213158295

GI number: 213158295

Start: 3111225

End: 3112184

Strand: Direct

Name: htrB [C]

Synonym: AB57_3019

Alternate gene names: 213158295

Gene position: 3111225-3112184 (Clockwise)

Preceding gene: 213158292

Following gene: 213158300

Centisome position: 76.81

GC content: 38.65

Gene sequence:

>960_bases
ATGAACTATCAATTACTCAAAACATTTAGCCGCCAACCCATTCAATTTGGGCGTTTTCTTGCTCGTCTGTTAGCAGGACT
TGTAAATACTCTAAAAATTACTAGAACATCAAAAAGTATTGAGCTTAACTTAAGAATTGCGCTTCCGTATTTAACACCTC
AGCAGCGTATAGCGATTACAGAAAAAGCTGTAAGAAACGAATTAACTTCATATTTTGAGTTTTTAAGTATTTGGGGCTCA
TCAAATAGTAAAAATATCTCACGCATTCACCGTATTGAAGGTGAACATTTTTTTCATGAAGCATTGGCTGCAAAAAAAGG
TGTAGTTCTTATTGTTCCACATTTTGGTACGTGGGAAGTCATGAATGCATGGTGTGCTCAATTCACATCAATGACCATTT
TATATAAACCCGTTAAAAATGCTGATGCAGACCGTTTTGTGCGAGAAGCCCGTAGCCGTGAACAAGCGAATCTCGTCCCT
ACCGATGAAAGCGGCGTAAGACAAATTTTTAAAGCATTAAAACAAGGTGAAACGACAGTAATTTTGCCGGATCATACCCC
TAATGTGGGTGGAGATATGGTGAACTATTTTGGTGTTCCACTTGCCTCAAGTAATTTAAGCGCAAAACTCATCCAGAAAA
CTAAAGCAAAAGCTCTGTTTCTTTATGCGATCCGTAATGAAAACGATGGCTTTACCATGCATATCGAGCCAATGGATGAG
AAAATCTATGAGGGTACTGCGGACGATGGAACGTATGTCATCCATCAAGCGATTGAGCAACTCATTTATCAATATCCAGA
ACATTATCACTGGAGCTATAAACGTTTTAAAGCGAACCCTGCTTTAGACAATATCTATAATATCGATCCGACAGAAGCAC
TTAAAATTGTGGATAGGCTCAAAGCAGAAGCTTTAAAAACCTCTACTCAACCAGAGCCTATCCAAACGTCGCTCATGTAA

Upstream 100 bases:

>100_bases
GTCTAAATAATATGATTTCATTTATAATATTTTTGTCTTTTTTTACTTGTTGTTTCTTCCTTACTTACTGCTATAGATGA
CTAGACCAGATTCAAAAAGC

Downstream 100 bases:

>100_bases
AACTATTTTGTGGTTTTCCAACACAAAACTTAAGGTTCCTTGTTCCACAGTGCTTTTTAGCGGAATATGCAGAGCTTTTA
AACGTGCTATAACTTGTTGG

Product: lipid A biosynthesis acyltransferase

Products: KDO2-(lauroyl)-lipid IVA [C]

Alternate protein names: Lipid A Biosynthesis Acyltransferase; Lauroyl/Myristoyl Acyltransferase; Lipid A Biosynthesis-Lipid IVA Acyltransferase; Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase Superfamily; Lipid A Biosynthesis Lauroyl Acyltransferase Subfamily; Acyltransferase Protein; Lipid A Biosynthesis Palmitoleoyl Acyltransferase; Lipid A Biosynthesis Acyltransferase Family; Lauroyl Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase; Decanoyltransferase LpxX; Lipid A Biosynthesis Lauroyl; Lipid A Acyl Transferase; Lipid A Biosynthesis Lauroylacyltransferase; Lauryl-Acyl Carrier Protein-Dependent Acyltransferase

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MNYQLLKTFSRQPIQFGRFLARLLAGLVNTLKITRTSKSIELNLRIALPYLTPQQRIAITEKAVRNELTSYFEFLSIWGS
SNSKNISRIHRIEGEHFFHEALAAKKGVVLIVPHFGTWEVMNAWCAQFTSMTILYKPVKNADADRFVREARSREQANLVP
TDESGVRQIFKALKQGETTVILPDHTPNVGGDMVNYFGVPLASSNLSAKLIQKTKAKALFLYAIRNENDGFTMHIEPMDE
KIYEGTADDGTYVIHQAIEQLIYQYPEHYHWSYKRFKANPALDNIYNIDPTEALKIVDRLKAEALKTSTQPEPIQTSLM

Sequences:

>Translated_319_residues
MNYQLLKTFSRQPIQFGRFLARLLAGLVNTLKITRTSKSIELNLRIALPYLTPQQRIAITEKAVRNELTSYFEFLSIWGS
SNSKNISRIHRIEGEHFFHEALAAKKGVVLIVPHFGTWEVMNAWCAQFTSMTILYKPVKNADADRFVREARSREQANLVP
TDESGVRQIFKALKQGETTVILPDHTPNVGGDMVNYFGVPLASSNLSAKLIQKTKAKALFLYAIRNENDGFTMHIEPMDE
KIYEGTADDGTYVIHQAIEQLIYQYPEHYHWSYKRFKANPALDNIYNIDPTEALKIVDRLKAEALKTSTQPEPIQTSLM
>Mature_319_residues
MNYQLLKTFSRQPIQFGRFLARLLAGLVNTLKITRTSKSIELNLRIALPYLTPQQRIAITEKAVRNELTSYFEFLSIWGS
SNSKNISRIHRIEGEHFFHEALAAKKGVVLIVPHFGTWEVMNAWCAQFTSMTILYKPVKNADADRFVREARSREQANLVP
TDESGVRQIFKALKQGETTVILPDHTPNVGGDMVNYFGVPLASSNLSAKLIQKTKAKALFLYAIRNENDGFTMHIEPMDE
KIYEGTADDGTYVIHQAIEQLIYQYPEHYHWSYKRFKANPALDNIYNIDPTEALKIVDRLKAEALKTSTQPEPIQTSLM

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787292, Length=251, Percent_Identity=22.7091633466135, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.- [C]

Molecular weight: Translated: 36425; Mature: 36425

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYQLLKTFSRQPIQFGRFLARLLAGLVNTLKITRTSKSIELNLRIALPYLTPQQRIAIT
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEEECCCCCCHHHHHH
EKAVRNELTSYFEFLSIWGSSNSKNISRIHRIEGEHFFHEALAAKKGVVLIVPHFGTWEV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCHHH
MNAWCAQFTSMTILYKPVKNADADRFVREARSREQANLVPTDESGVRQIFKALKQGETTV
HHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEE
ILPDHTPNVGGDMVNYFGVPLASSNLSAKLIQKTKAKALFLYAIRNENDGFTMHIEPMDE
EECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCHH
KIYEGTADDGTYVIHQAIEQLIYQYPEHYHWSYKRFKANPALDNIYNIDPTEALKIVDRL
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCCCCCCHHHHHHHHHHH
KAEALKTSTQPEPIQTSLM
HHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure
MNYQLLKTFSRQPIQFGRFLARLLAGLVNTLKITRTSKSIELNLRIALPYLTPQQRIAIT
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHEEEECCCEEEEEEEEEECCCCCCHHHHHH
EKAVRNELTSYFEFLSIWGSSNSKNISRIHRIEGEHFFHEALAAKKGVVLIVPHFGTWEV
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEECCCCCHHH
MNAWCAQFTSMTILYKPVKNADADRFVREARSREQANLVPTDESGVRQIFKALKQGETTV
HHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEE
ILPDHTPNVGGDMVNYFGVPLASSNLSAKLIQKTKAKALFLYAIRNENDGFTMHIEPMDE
EECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHCCCEEEEEEEECCCCCEEEEEECCHH
KIYEGTADDGTYVIHQAIEQLIYQYPEHYHWSYKRFKANPALDNIYNIDPTEALKIVDRL
HHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHEEECCCCCCCCCCCCHHHHHHHHHHH
KAEALKTSTQPEPIQTSLM
HHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; lauroyl-ACP [C]

Specific reaction: KDO2-lipid IVA + lauroyl-ACP = KDO2-(lauroyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA