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The map label for this gene is queC [H]

Identifier: 213158262

GI number: 213158262

Start: 3076550

End: 3077221

Strand: Direct

Name: queC [H]

Synonym: AB57_2982

Alternate gene names: 213158262

Gene position: 3076550-3077221 (Clockwise)

Preceding gene: 213158261

Following gene: 213158263

Centisome position: 75.95

GC content: 42.86

Gene sequence:

>672_bases
ATGCGCCCTCGTGCCATTGTTTTACTTTCAGGCGGCTTAGACTCAACCACTTGCCTAGCTTGGGCACAAGCGCGCTATGA
ATGTATTGCTATTAGTTTTATGTATGGTCAACGCTCAACCACTGAACTTGATGCTGCAAAAGCATTAGCTCAGCGTGCAG
GTGTTGAACACCGTGTAATTAATATCGATTTAGCCAATTTAGGCGGGTCTGCACTTACAGATCATAACATTGCTGTACCA
GAACAATTACAAGAAGGTATTCCTGTAACTTATGTACCAGCACGTAACACAATTTTCCTCTCTTATGCCTTAGCAGCAGC
AGAAGTTTTCAACGCTGAAGCAATTGTTATCGGCATCAATGCTGTTGATTATTCAGGATATCCTGACTGTCGCCCAGAAT
TTATTGATGCTTTTGCCAATATGGCTCGTTTAGCAACTAAAGCTGGCGTGGAAGGAAAACCTCTTAAATTTGAAACACCC
CTGTTACATTTATCCAAAGCGAATATTATACGTTTAGGGATTGAACATGGCGTAGACTATAGTCAAACGGTATCTTGCTA
CCAAGCAGATGCTCAAGGACGTGCGTGTGGTAAATGTGACAGTTGCCGTTTGCGTAAAGAAGGCTTTATCGACGCTGGTG
TTACCGATCCAACACGCTATATACCGCAATAA

Upstream 100 bases:

>100_bases
CCTGTACGTTTCCAGCTACAGTTACACAAACTGCTCTGGAACGATGAATCAGGTCGCTAAGCGTTCAATAAAATAAATCA
TTCCGAATATGGAGAAAAAT

Downstream 100 bases:

>100_bases
GTAGGTAAAATTTATGAAGTTGTTAAAATCAAATCTTATTCTTTCATCTTTATTCTCAGCAGCTGCACTTATGGCTGGTT
CAGCTCAAGCAGCTGAAAAC

Product: ExsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRPRAIVLLSGGLDSTTCLAWAQARYECIAISFMYGQRSTTELDAAKALAQRAGVEHRVINIDLANLGGSALTDHNIAVP
EQLQEGIPVTYVPARNTIFLSYALAAAEVFNAEAIVIGINAVDYSGYPDCRPEFIDAFANMARLATKAGVEGKPLKFETP
LLHLSKANIIRLGIEHGVDYSQTVSCYQADAQGRACGKCDSCRLRKEGFIDAGVTDPTRYIPQ

Sequences:

>Translated_223_residues
MRPRAIVLLSGGLDSTTCLAWAQARYECIAISFMYGQRSTTELDAAKALAQRAGVEHRVINIDLANLGGSALTDHNIAVP
EQLQEGIPVTYVPARNTIFLSYALAAAEVFNAEAIVIGINAVDYSGYPDCRPEFIDAFANMARLATKAGVEGKPLKFETP
LLHLSKANIIRLGIEHGVDYSQTVSCYQADAQGRACGKCDSCRLRKEGFIDAGVTDPTRYIPQ
>Mature_223_residues
MRPRAIVLLSGGLDSTTCLAWAQARYECIAISFMYGQRSTTELDAAKALAQRAGVEHRVINIDLANLGGSALTDHNIAVP
EQLQEGIPVTYVPARNTIFLSYALAAAEVFNAEAIVIGINAVDYSGYPDCRPEFIDAFANMARLATKAGVEGKPLKFETP
LLHLSKANIIRLGIEHGVDYSQTVSCYQADAQGRACGKCDSCRLRKEGFIDAGVTDPTRYIPQ

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=223, Percent_Identity=39.9103139013453, Blast_Score=147, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 24126; Mature: 24126

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPRAIVLLSGGLDSTTCLAWAQARYECIAISFMYGQRSTTELDAAKALAQRAGVEHRVI
CCCCEEEEEECCCCCHHHHHHHHCCEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEE
NIDLANLGGSALTDHNIAVPEQLQEGIPVTYVPARNTIFLSYALAAAEVFNAEAIVIGIN
EEEECCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCEEEEHHHHHHHHHCCCCEEEEEEE
AVDYSGYPDCRPEFIDAFANMARLATKAGVEGKPLKFETPLLHLSKANIIRLGIEHGVDY
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEECCCCEEEEEHHHCCCH
SQTVSCYQADAQGRACGKCDSCRLRKEGFIDAGVTDPTRYIPQ
HHHHHHEECCCCCCCCCCCCCCCCCCCCCEECCCCCCHHCCCC
>Mature Secondary Structure
MRPRAIVLLSGGLDSTTCLAWAQARYECIAISFMYGQRSTTELDAAKALAQRAGVEHRVI
CCCCEEEEEECCCCCHHHHHHHHCCEEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEE
NIDLANLGGSALTDHNIAVPEQLQEGIPVTYVPARNTIFLSYALAAAEVFNAEAIVIGIN
EEEECCCCCCCCCCCCCCCCHHHHCCCCEEEECCCCEEEEHHHHHHHHHCCCCEEEEEEE
AVDYSGYPDCRPEFIDAFANMARLATKAGVEGKPLKFETPLLHLSKANIIRLGIEHGVDY
EEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEECCCCEEEEEHHHCCCH
SQTVSCYQADAQGRACGKCDSCRLRKEGFIDAGVTDPTRYIPQ
HHHHHHEECCCCCCCCCCCCCCCCCCCCCEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA