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The map label for this gene is era [H]

Identifier: 213158241

GI number: 213158241

Start: 3056093

End: 3057121

Strand: Reverse

Name: era [H]

Synonym: AB57_2960

Alternate gene names: 213158241

Gene position: 3057121-3056093 (Counterclockwise)

Preceding gene: 213158242

Following gene: 213158240

Centisome position: 75.47

GC content: 37.8

Gene sequence:

>1029_bases
ATGTCGATGCATTCTGATCAAATCAATCCAGATTCAAACGAAAACCAAGATCCAAACAATCTGATTGATCAATTTTTTAG
TTCCAAAGGCGTTACAATTCCTTCGGATTTTAAGAGCGGATTTGTGGCGATTGTAGGACGTCCAAATGTGGGTAAATCTA
CCCTCATGAACCATTTATTGGGCCAAAAACTCTCTATTACTTCACGTAAACCTCAAACGACACGCCATAAAATTATTGGT
ATTGATTCGCGTGAAAAAATGCAAGCGGTTTATGTCGATACCCCAGGTATGCATAAGAAAGAAGTACGTGCAATCAATAA
AATGATGAACCGTGCTGCGCATTCTGCGTTACGTGACGTGAATTTAGTCTTATTTGTTATTGATGCCCACAAGTGGACTC
AAAATGACGATTTAGTTCTTGAGAAACTCAAGAATGCTGATATGCCAGTTATTTTGGTGATTAATAAAGCTGATACTTTT
GGAGATAAGAGAGAGATTCTCCCTTTAATTCAAGAACGTGCCAAACTTATGAATTTTGCTGAGATTGTTCCTGTTTCTGC
ACTCCGTGGAGCAAACTTAGAGCACTTAAGTGAAACGATTGAAAAATATCTTCCTTATCAGCCACCTTTATATTCATTCG
ATCAAATTACGGACCGTTCAGAGCGCTTCTTGGCAAGTGAAATCATCCGTGAAAAAATCATGCGTCAGTTGGGTGAAGAG
CTACCTTATGATTTAACAGTACAAATTGAATCTTTCAAAACGGAAGAAGCAACTGTTAATGAAAAAACTGGTCGTTTAAA
ACCAGCATGTACCTATATTGATGCCACTATTTTTGTGGATCGTCCTGGTCAAAAAGCGATTGTAATTGGTGAAAAAGGTG
CCAAGCTTAAAACAATTGGCATGGATGCACGTAAAGACATGGAAAAAATGTTCGAACAAAAGATCATGCTTACCTTATGG
GTTAAGGTCAAAGGCGGTTGGTCTGATGATGAACGTGCTTTAAAAAGTTTAGGATATAGTGATATCTAA

Upstream 100 bases:

>100_bases
TAGATGGTTTATCAAAAATTCATGGTGAGGGGTCAAGTCGTCGTTTTGCCGAGCAGGCAGCAGCGGCGGAAATTTTAAAG
TTATTGGAGCAATAACCTGC

Downstream 100 bases:

>100_bases
AAAGTAGGGAATACTGGTATGAAAGCAATTACATCAATATTGATTATCGTTGGATGTACATCGATGTTGCAAGGTTGTGT
ATATAAGCTTGTAACCGTAC

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MSMHSDQINPDSNENQDPNNLIDQFFSSKGVTIPSDFKSGFVAIVGRPNVGKSTLMNHLLGQKLSITSRKPQTTRHKIIG
IDSREKMQAVYVDTPGMHKKEVRAINKMMNRAAHSALRDVNLVLFVIDAHKWTQNDDLVLEKLKNADMPVILVINKADTF
GDKREILPLIQERAKLMNFAEIVPVSALRGANLEHLSETIEKYLPYQPPLYSFDQITDRSERFLASEIIREKIMRQLGEE
LPYDLTVQIESFKTEEATVNEKTGRLKPACTYIDATIFVDRPGQKAIVIGEKGAKLKTIGMDARKDMEKMFEQKIMLTLW
VKVKGGWSDDERALKSLGYSDI

Sequences:

>Translated_342_residues
MSMHSDQINPDSNENQDPNNLIDQFFSSKGVTIPSDFKSGFVAIVGRPNVGKSTLMNHLLGQKLSITSRKPQTTRHKIIG
IDSREKMQAVYVDTPGMHKKEVRAINKMMNRAAHSALRDVNLVLFVIDAHKWTQNDDLVLEKLKNADMPVILVINKADTF
GDKREILPLIQERAKLMNFAEIVPVSALRGANLEHLSETIEKYLPYQPPLYSFDQITDRSERFLASEIIREKIMRQLGEE
LPYDLTVQIESFKTEEATVNEKTGRLKPACTYIDATIFVDRPGQKAIVIGEKGAKLKTIGMDARKDMEKMFEQKIMLTLW
VKVKGGWSDDERALKSLGYSDI
>Mature_341_residues
SMHSDQINPDSNENQDPNNLIDQFFSSKGVTIPSDFKSGFVAIVGRPNVGKSTLMNHLLGQKLSITSRKPQTTRHKIIGI
DSREKMQAVYVDTPGMHKKEVRAINKMMNRAAHSALRDVNLVLFVIDAHKWTQNDDLVLEKLKNADMPVILVINKADTFG
DKREILPLIQERAKLMNFAEIVPVSALRGANLEHLSETIEKYLPYQPPLYSFDQITDRSERFLASEIIREKIMRQLGEEL
PYDLTVQIESFKTEEATVNEKTGRLKPACTYIDATIFVDRPGQKAIVIGEKGAKLKTIGMDARKDMEKMFEQKIMLTLWV
KVKGGWSDDERALKSLGYSDI

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=351, Percent_Identity=25.0712250712251, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1788919, Length=303, Percent_Identity=56.1056105610561, Blast_Score=347, Evalue=9e-97,
Organism=Escherichia coli, GI87082120, Length=166, Percent_Identity=33.7349397590361, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24646434, Length=323, Percent_Identity=27.5541795665635, Blast_Score=108, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 38791; Mature: 38660

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMHSDQINPDSNENQDPNNLIDQFFSSKGVTIPSDFKSGFVAIVGRPNVGKSTLMNHLL
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
GQKLSITSRKPQTTRHKIIGIDSREKMQAVYVDTPGMHKKEVRAINKMMNRAAHSALRDV
CCCEECCCCCCCCCCCEEEECCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
NLVLFVIDAHKWTQNDDLVLEKLKNADMPVILVINKADTFGDKREILPLIQERAKLMNFA
EEEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
EIVPVSALRGANLEHLSETIEKYLPYQPPLYSFDQITDRSERFLASEIIREKIMRQLGEE
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LPYDLTVQIESFKTEEATVNEKTGRLKPACTYIDATIFVDRPGQKAIVIGEKGAKLKTIG
CCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEECCCCCEEEEEC
MDARKDMEKMFEQKIMLTLWVKVKGGWSDDERALKSLGYSDI
CCHHHHHHHHHHHHEEEEEEEEEECCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
SMHSDQINPDSNENQDPNNLIDQFFSSKGVTIPSDFKSGFVAIVGRPNVGKSTLMNHLL
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHH
GQKLSITSRKPQTTRHKIIGIDSREKMQAVYVDTPGMHKKEVRAINKMMNRAAHSALRDV
CCCEECCCCCCCCCCCEEEECCCHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCC
NLVLFVIDAHKWTQNDDLVLEKLKNADMPVILVINKADTFGDKREILPLIQERAKLMNFA
EEEEEEEECCCCCCCCHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
EIVPVSALRGANLEHLSETIEKYLPYQPPLYSFDQITDRSERFLASEIIREKIMRQLGEE
HHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LPYDLTVQIESFKTEEATVNEKTGRLKPACTYIDATIFVDRPGQKAIVIGEKGAKLKTIG
CCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCEEEEECCCCCEEEEEC
MDARKDMEKMFEQKIMLTLWVKVKGGWSDDERALKSLGYSDI
CCHHHHHHHHHHHHEEEEEEEEEECCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA