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The map label for this gene is aatA [H]

Identifier: 213158232

GI number: 213158232

Start: 3049453

End: 3050688

Strand: Direct

Name: aatA [H]

Synonym: AB57_2951

Alternate gene names: 213158232

Gene position: 3049453-3050688 (Clockwise)

Preceding gene: 213158230

Following gene: 213158234

Centisome position: 75.29

GC content: 41.83

Gene sequence:

>1236_bases
GTGGACGTACGTCTTTCTGATCGTGTCAATGCTATCAAACCGTCCCCTACACTTGCTGTAACTAATAAAGCTGCTGAGCT
TAAAGCTGCTGGCAAGAACGTGATTGGTTTGGGTGCTGGCGAGCCAGATTTTGATACCCCTCAACACATCAAAGATGCTG
CAATTGAAGCGATTAATAATGGCTTCACCAAATATACGGCTGTAGATGGTACTCCTGGGTTAAAAAAAGCAATTATTGCT
AAATTAAAGCGTGATAATAATCTTGATTACCAACCTAACCAGATTTTGGTTTCTTGTGGCGGTAAGCAAAGCTTCTTTAA
CTTGGCACTAGCATTATTAAACAAGGGTGATGAAGTGATCATCCCTGCGCCATTCTGGGTAAGCTATCCAGATATGGTCA
TTATTGCTGAAGGTACGCCTGTTATCGTGAAATGTGGCGAAGAGCAACGTTTCAAAATTACACCTGAACAATTAGAAGCG
GCGATTACTCCTAACACTCGTTTAGTGGTATTAAACAGCCCATCTAACCCGACAGGTATGATTTACAGCAAAGCTGAATT
AGAAGCTTTAGCTGAGGTTTTACGTCGTCATCCGCAAGTATTTGTTGCATCTGACGACATGTATGAACCAATTCGTTGGG
AAGATGAGTTCTACAATATTGCAACTGTTGCACCTGATTTATATGACCGCACGATTGTTTTAAATGGTGTTTCTAAAGCA
TATGCAATGACAGGTTGGCGTATTGGCTATGCAGCCGGCCCAGCAAAAATCATTGGTGCAATGAAAAAAATCCAGTCTCA
ATCAACTTCTAACCCGACTTCAATTTCGCAAGTTGCTGCTGAAGCTGCGTTGAATGGTCCACAAGATGTTTTAAAACCAA
TGATTGAAGCGTTTAAACGTCGTCATGACTTAGTGGTTAATGGCTTAAACGACATCAAAGGGATCTCTTGCTTACCTGCT
GATGGCGCTTTCTACGCGTATGCAAACATTCGCCCTCTTATTCGTGCAAAAGGCTTAAAATCTTGCACAGAATTCTCTGA
GTGGTTACTTGAAGAAACTGGCGTAGCAGTCGTTCCTGGTGATGCATTTGGTTTAGGTGGTTTCATGCGTATTTCATATG
CAACAGCTGACGAAGTACTTGTTGATGCGTTAGCACGTATCAAAAAAGCTGCTGAATCAATCGAAGGCGTTGATGCTGCG
ATTGCATCTATCGAAGCTGAAAAAGCTACTAAATAA

Upstream 100 bases:

>100_bases
AACTTTTTTACATCTAAAAATCCCCACATCCGCAAATTGCTTAATTTTTGCGATAAGATAGTGTGCTTTTTATTTTTAAT
CCCATAAGAGGAATATTGCC

Downstream 100 bases:

>100_bases
TTTGAAAATATAAAAAAGGCCTCAGAATTGAGGCCTTTTTTATAATTAAAATTATTCTAAATTAAATAAAGCTGACACCT
CAGCCTCAGTCAGTTTTTTT

Product: aspartate aminotransferase A

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MDVRLSDRVNAIKPSPTLAVTNKAAELKAAGKNVIGLGAGEPDFDTPQHIKDAAIEAINNGFTKYTAVDGTPGLKKAIIA
KLKRDNNLDYQPNQILVSCGGKQSFFNLALALLNKGDEVIIPAPFWVSYPDMVIIAEGTPVIVKCGEEQRFKITPEQLEA
AITPNTRLVVLNSPSNPTGMIYSKAELEALAEVLRRHPQVFVASDDMYEPIRWEDEFYNIATVAPDLYDRTIVLNGVSKA
YAMTGWRIGYAAGPAKIIGAMKKIQSQSTSNPTSISQVAAEAALNGPQDVLKPMIEAFKRRHDLVVNGLNDIKGISCLPA
DGAFYAYANIRPLIRAKGLKSCTEFSEWLLEETGVAVVPGDAFGLGGFMRISYATADEVLVDALARIKKAAESIEGVDAA
IASIEAEKATK

Sequences:

>Translated_411_residues
MDVRLSDRVNAIKPSPTLAVTNKAAELKAAGKNVIGLGAGEPDFDTPQHIKDAAIEAINNGFTKYTAVDGTPGLKKAIIA
KLKRDNNLDYQPNQILVSCGGKQSFFNLALALLNKGDEVIIPAPFWVSYPDMVIIAEGTPVIVKCGEEQRFKITPEQLEA
AITPNTRLVVLNSPSNPTGMIYSKAELEALAEVLRRHPQVFVASDDMYEPIRWEDEFYNIATVAPDLYDRTIVLNGVSKA
YAMTGWRIGYAAGPAKIIGAMKKIQSQSTSNPTSISQVAAEAALNGPQDVLKPMIEAFKRRHDLVVNGLNDIKGISCLPA
DGAFYAYANIRPLIRAKGLKSCTEFSEWLLEETGVAVVPGDAFGLGGFMRISYATADEVLVDALARIKKAAESIEGVDAA
IASIEAEKATK
>Mature_411_residues
MDVRLSDRVNAIKPSPTLAVTNKAAELKAAGKNVIGLGAGEPDFDTPQHIKDAAIEAINNGFTKYTAVDGTPGLKKAIIA
KLKRDNNLDYQPNQILVSCGGKQSFFNLALALLNKGDEVIIPAPFWVSYPDMVIIAEGTPVIVKCGEEQRFKITPEQLEA
AITPNTRLVVLNSPSNPTGMIYSKAELEALAEVLRRHPQVFVASDDMYEPIRWEDEFYNIATVAPDLYDRTIVLNGVSKA
YAMTGWRIGYAAGPAKIIGAMKKIQSQSTSNPTSISQVAAEAALNGPQDVLKPMIEAFKRRHDLVVNGLNDIKGISCLPA
DGAFYAYANIRPLIRAKGLKSCTEFSEWLLEETGVAVVPGDAFGLGGFMRISYATADEVLVDALARIKKAAESIEGVDAA
IASIEAEKATK

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=397, Percent_Identity=26.9521410579345, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI56713256, Length=397, Percent_Identity=26.9521410579345, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI95147551, Length=383, Percent_Identity=25.065274151436, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI169881279, Length=383, Percent_Identity=25.065274151436, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI169881281, Length=380, Percent_Identity=22.8947368421053, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4507369, Length=397, Percent_Identity=24.4332493702771, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=23.8482384823848, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=23.8482384823848, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786816, Length=370, Percent_Identity=28.1081081081081, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1788722, Length=408, Percent_Identity=30.1470588235294, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1788627, Length=362, Percent_Identity=30.939226519337, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=408, Percent_Identity=28.921568627451, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71994472, Length=408, Percent_Identity=28.921568627451, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17567369, Length=417, Percent_Identity=28.2973621103118, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17567663, Length=374, Percent_Identity=22.9946524064171, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71981209, Length=364, Percent_Identity=23.6263736263736, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=26.1964735516373, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6323118, Length=352, Percent_Identity=22.4431818181818, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573069, Length=362, Percent_Identity=25.1381215469613, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24646114, Length=362, Percent_Identity=25.1381215469613, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573067, Length=362, Percent_Identity=25.1381215469613, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI28573065, Length=362, Percent_Identity=25.1381215469613, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=22.4867724867725, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45551451, Length=361, Percent_Identity=24.3767313019391, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641770, Length=361, Percent_Identity=24.3767313019391, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641760, Length=361, Percent_Identity=24.3767313019391, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641768, Length=361, Percent_Identity=24.3767313019391, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641766, Length=361, Percent_Identity=24.3767313019391, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24641764, Length=361, Percent_Identity=24.3767313019391, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44309; Mature: 44309

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRLSDRVNAIKPSPTLAVTNKAAELKAAGKNVIGLGAGEPDFDTPQHIKDAAIEAINN
CCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
GFTKYTAVDGTPGLKKAIIAKLKRDNNLDYQPNQILVSCGGKQSFFNLALALLNKGDEVI
CCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEE
IPAPFWVSYPDMVIIAEGTPVIVKCGEEQRFKITPEQLEAAITPNTRLVVLNSPSNPTGM
ECCCCEECCCCEEEEECCCEEEEECCCCCCEEECHHHHHEEECCCEEEEEEECCCCCCEE
IYSKAELEALAEVLRRHPQVFVASDDMYEPIRWEDEFYNIATVAPDLYDRTIVLNGVSKA
EEEHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHEEEEEECCCHHCCEEEEECCHHH
YAMTGWRIGYAAGPAKIIGAMKKIQSQSTSNPTSISQVAAEAALNGPQDVLKPMIEAFKR
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RHDLVVNGLNDIKGISCLPADGAFYAYANIRPLIRAKGLKSCTEFSEWLLEETGVAVVPG
HHHHEEECCCCCCCCEEECCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCEEEECC
DAFGLGGFMRISYATADEVLVDALARIKKAAESIEGVDAAIASIEAEKATK
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDVRLSDRVNAIKPSPTLAVTNKAAELKAAGKNVIGLGAGEPDFDTPQHIKDAAIEAINN
CCCCCCCCCCCCCCCCCEEEECCHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHC
GFTKYTAVDGTPGLKKAIIAKLKRDNNLDYQPNQILVSCGGKQSFFNLALALLNKGDEVI
CCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCEEE
IPAPFWVSYPDMVIIAEGTPVIVKCGEEQRFKITPEQLEAAITPNTRLVVLNSPSNPTGM
ECCCCEECCCCEEEEECCCEEEEECCCCCCEEECHHHHHEEECCCEEEEEEECCCCCCEE
IYSKAELEALAEVLRRHPQVFVASDDMYEPIRWEDEFYNIATVAPDLYDRTIVLNGVSKA
EEEHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHEEEEEECCCHHCCEEEEECCHHH
YAMTGWRIGYAAGPAKIIGAMKKIQSQSTSNPTSISQVAAEAALNGPQDVLKPMIEAFKR
HHHCCEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHH
RHDLVVNGLNDIKGISCLPADGAFYAYANIRPLIRAKGLKSCTEFSEWLLEETGVAVVPG
HHHHEEECCCCCCCCEEECCCCCEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCEEEECC
DAFGLGGFMRISYATADEVLVDALARIKKAAESIEGVDAAIASIEAEKATK
CCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA