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The map label for this gene is mrdB [H]

Identifier: 213158037

GI number: 213158037

Start: 2813265

End: 2814344

Strand: Direct

Name: mrdB [H]

Synonym: AB57_2748

Alternate gene names: 213158037

Gene position: 2813265-2814344 (Clockwise)

Preceding gene: 213158036

Following gene: 213158038

Centisome position: 69.45

GC content: 40.37

Gene sequence:

>1080_bases
ATGCAACCTTCACGCTGGCAGCAGCTTCATATTGACCCTTGGTTATGCCTATTTTTATTCCTAAATGCATTGTTAGGTTT
AACGGTACTTTATAGTGCATCTGCACAAGATGTGGGACTCGTCAGTAAACAGGCCATGAGCTTTGGTATCGGCTTTCTGG
TCATGATTAGCCTAGCGCAAATTCCACCCAAGGTTTATCAAGCTTTTTCACCTTATTTTTATTTATTTGGCCTGTTTTCC
TTAATTGGCGTTATGGTTTTTGGTGAAGTTCGCATGGGTGCTCAACGCTGGATCGATATTCCAGGGTTCGGGAGTGTTCA
ACCCAGCGAATTTATGAAAATTGGCATGCCAATGATGGTTGCATGGTTTTTAGCTCGCAAACCTCTTCCTCCTAGCTTCT
CGCAGGTTATTTTGTCTTTAATGTTAATTGGTGTTCCATTTTTACTTATTGCAGAACAGCCTGACCTAGGAACATCACTA
TTAGTATTAGCAAGTGGGATTTTTGTACTGTTCTTAAGTGGGTTATCTTGGCGCATGATCGGTGCAGCAGCAGCTTGTGC
AGCTATTGTGATTCCAATTGCATGGGAATTCCTTTTACACGACTATCAACGTCAACGAGTATTAACGTTGCTTGACCCAG
AAGCGGATGCTTTAGGAACAGGCTGGAACATTATTCAGTCCAAAACAGCAATCGGTTCTGGTGGGTTCTCAGGTAAAGGT
TTCCTCGAAGGTACTCAATCACATTTACACTTCTTACCAGAAGGCCATACTGACTTTATTATTGCTGCTTACTCAGAAGA
ATTCGGTTTAATTGGTGTACTTATATTAGTAATTCTTTATTCGGCCATTATTTTTAGAACATTTCAAATCGGTTTACAAA
GTTTTCACAATTATGGCCGATTAGTGGCTGGCGCGTTTGGTTTGTCTTTTTTTGTTTATGTATTTGTAAACGCAGGAATG
GTCAGTGGTATTTTACCTGTAGTGGGTGTTCCCTTACCTTTTATGAGTTATGGCGGTACCGCTATTATTACTTTAATGGC
CACTTTTGGTTTAGTCATGTCTATTCATACACATCGATAA

Upstream 100 bases:

>100_bases
ATGCGCCAAGCACTGATTGACCTTTAGTTAAAGCCGCATGTCTCCTAGTCCACAATATAAATTTTTACGCCAAGCTCCTC
GAGATGGCCTTAGTACTGCC

Downstream 100 bases:

>100_bases
TCTGGAATTTAAAAAAGATATGTTGTCTCAATTTGTTAATAAAACTTTAAAAGTGCTTGCCTTGTGTACAGGCCTTATTA
GCACAAGTCATTTTGCTCAG

Product: rod shape-determining protein RodA (EsvE3)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MQPSRWQQLHIDPWLCLFLFLNALLGLTVLYSASAQDVGLVSKQAMSFGIGFLVMISLAQIPPKVYQAFSPYFYLFGLFS
LIGVMVFGEVRMGAQRWIDIPGFGSVQPSEFMKIGMPMMVAWFLARKPLPPSFSQVILSLMLIGVPFLLIAEQPDLGTSL
LVLASGIFVLFLSGLSWRMIGAAAACAAIVIPIAWEFLLHDYQRQRVLTLLDPEADALGTGWNIIQSKTAIGSGGFSGKG
FLEGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVLILVILYSAIIFRTFQIGLQSFHNYGRLVAGAFGLSFFVYVFVNAGM
VSGILPVVGVPLPFMSYGGTAIITLMATFGLVMSIHTHR

Sequences:

>Translated_359_residues
MQPSRWQQLHIDPWLCLFLFLNALLGLTVLYSASAQDVGLVSKQAMSFGIGFLVMISLAQIPPKVYQAFSPYFYLFGLFS
LIGVMVFGEVRMGAQRWIDIPGFGSVQPSEFMKIGMPMMVAWFLARKPLPPSFSQVILSLMLIGVPFLLIAEQPDLGTSL
LVLASGIFVLFLSGLSWRMIGAAAACAAIVIPIAWEFLLHDYQRQRVLTLLDPEADALGTGWNIIQSKTAIGSGGFSGKG
FLEGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVLILVILYSAIIFRTFQIGLQSFHNYGRLVAGAFGLSFFVYVFVNAGM
VSGILPVVGVPLPFMSYGGTAIITLMATFGLVMSIHTHR
>Mature_359_residues
MQPSRWQQLHIDPWLCLFLFLNALLGLTVLYSASAQDVGLVSKQAMSFGIGFLVMISLAQIPPKVYQAFSPYFYLFGLFS
LIGVMVFGEVRMGAQRWIDIPGFGSVQPSEFMKIGMPMMVAWFLARKPLPPSFSQVILSLMLIGVPFLLIAEQPDLGTSL
LVLASGIFVLFLSGLSWRMIGAAAACAAIVIPIAWEFLLHDYQRQRVLTLLDPEADALGTGWNIIQSKTAIGSGGFSGKG
FLEGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVLILVILYSAIIFRTFQIGLQSFHNYGRLVAGAFGLSFFVYVFVNAGM
VSGILPVVGVPLPFMSYGGTAIITLMATFGLVMSIHTHR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=354, Percent_Identity=55.3672316384181, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1786277, Length=314, Percent_Identity=30.5732484076433, Blast_Score=139, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 39234; Mature: 39234

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPSRWQQLHIDPWLCLFLFLNALLGLTVLYSASAQDVGLVSKQAMSFGIGFLVMISLAQ
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPPKVYQAFSPYFYLFGLFSLIGVMVFGEVRMGAQRWIDIPGFGSVQPSEFMKIGMPMMV
CCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHEECCCCCCCCCHHHHHHHCHHHHH
AWFLARKPLPPSFSQVILSLMLIGVPFLLIAEQPDLGTSLLVLASGIFVLFLSGLSWRMI
HHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHH
GAAAACAAIVIPIAWEFLLHDYQRQRVLTLLDPEADALGTGWNIIQSKTAIGSGGFSGKG
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCC
FLEGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVLILVILYSAIIFRTFQIGLQSFHNYGR
CCCCCHHHHEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAGAFGLSFFVYVFVNAGMVSGILPVVGVPLPFMSYGGTAIITLMATFGLVMSIHTHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQPSRWQQLHIDPWLCLFLFLNALLGLTVLYSASAQDVGLVSKQAMSFGIGFLVMISLAQ
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPPKVYQAFSPYFYLFGLFSLIGVMVFGEVRMGAQRWIDIPGFGSVQPSEFMKIGMPMMV
CCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHEECCCCCCCCCHHHHHHHCHHHHH
AWFLARKPLPPSFSQVILSLMLIGVPFLLIAEQPDLGTSLLVLASGIFVLFLSGLSWRMI
HHHHHCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHH
GAAAACAAIVIPIAWEFLLHDYQRQRVLTLLDPEADALGTGWNIIQSKTAIGSGGFSGKG
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCC
FLEGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVLILVILYSAIIFRTFQIGLQSFHNYGR
CCCCCHHHHEECCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVAGAFGLSFFVYVFVNAGMVSGILPVVGVPLPFMSYGGTAIITLMATFGLVMSIHTHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]