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The map label for this gene is apaH [H]

Identifier: 213157954

GI number: 213157954

Start: 3559245

End: 3560084

Strand: Reverse

Name: apaH [H]

Synonym: AB57_3448

Alternate gene names: 213157954

Gene position: 3560084-3559245 (Counterclockwise)

Preceding gene: 213157955

Following gene: 213157949

Centisome position: 87.89

GC content: 39.4

Gene sequence:

>840_bases
ATGACTAAGCGCTATAACTATATAATTGGAGATGTGCAAGGTTGTTTTGAGGCACTCAAAGCGCTATTAAAAGAAATACG
TTTTGACCCTGATCAAGATTTTATCTGGTTTGCTGGTGACTTGGTTGCACGTGGTGAAAACTCTATAGGTGCTCTACGTT
TTATTAAAAAACTAGCTGATCGAGGGGCTGCTGCTACCGTATTAGGTAACCATGATTTAACCCTGATTGCCGGTGCTCGT
GGTCTTAAGGAAATTAAAGAAAAAGATCGCACGCAGGATGTTATTGACGCCGTGGATGGTGATGATCTTATCGATTGGTT
ACGTAAACAGCCGTTATGTTTATTTCCAAATGAACAAACAATACTGACGCACGCAGGTGTACCTTGTATTTGGGATGCAC
AAAAAACTGCTGCATTGGCAAAAGAAGTTGAGGCTGTATTGGCGCATGATGATTTATCTGTGTTAGATGCATTTTTAGCT
GAAATGTATGGTTCAAAACCCGATCTTTGGACAGATGATTTGACAGGTAATGAGCGTTTACGTTGTATTACCAATTACTT
AACTCGTATGCGTTTAACTAATGCAGAAGGGGCTTTGGAGTTTAGTTTTAAAGATACTTTAGATGCACCAATGCCAGAAG
GTTATTTACCGTGGTTTGAATTTCCAAGTAAGGCTGCACAAACCCATCAAATATTTTTTGGACATTGGGCTGCTCTAGAG
GGTAGAACTATTAGTGAACACATCCAAAATGTTGATGGTGGTTGTGTATGGGGTAAAAACTTAATTGCTTATCGTCTTGA
AGATCAACAAGCTTTTTCTGTGAGCAACCCTGTTATGTAA

Upstream 100 bases:

>100_bases
AGAGGATGGTTTCGAGAAAGCAGGAGTCGACCCAATGGCTCGTCCAGAAACTTTAACTCTTGCAGAGTTTGTGGCTTTGG
CAGATCAAATGGTGGCATAA

Downstream 100 bases:

>100_bases
TAAAAAAAGCCGCTGAAGCGTCTTTTTTTATTTTTAAGATATTTATTCTAGGCGAATCCAGATCTGATTACGACCTAAAG
CAGATACCCCAAGGTAACCG

Product: diadenosine tetraphosphatase

Products: NA

Alternate protein names: Ap4A hydrolase; Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase; Diadenosine tetraphosphatase [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTKRYNYIIGDVQGCFEALKALLKEIRFDPDQDFIWFAGDLVARGENSIGALRFIKKLADRGAAATVLGNHDLTLIAGAR
GLKEIKEKDRTQDVIDAVDGDDLIDWLRKQPLCLFPNEQTILTHAGVPCIWDAQKTAALAKEVEAVLAHDDLSVLDAFLA
EMYGSKPDLWTDDLTGNERLRCITNYLTRMRLTNAEGALEFSFKDTLDAPMPEGYLPWFEFPSKAAQTHQIFFGHWAALE
GRTISEHIQNVDGGCVWGKNLIAYRLEDQQAFSVSNPVM

Sequences:

>Translated_279_residues
MTKRYNYIIGDVQGCFEALKALLKEIRFDPDQDFIWFAGDLVARGENSIGALRFIKKLADRGAAATVLGNHDLTLIAGAR
GLKEIKEKDRTQDVIDAVDGDDLIDWLRKQPLCLFPNEQTILTHAGVPCIWDAQKTAALAKEVEAVLAHDDLSVLDAFLA
EMYGSKPDLWTDDLTGNERLRCITNYLTRMRLTNAEGALEFSFKDTLDAPMPEGYLPWFEFPSKAAQTHQIFFGHWAALE
GRTISEHIQNVDGGCVWGKNLIAYRLEDQQAFSVSNPVM
>Mature_278_residues
TKRYNYIIGDVQGCFEALKALLKEIRFDPDQDFIWFAGDLVARGENSIGALRFIKKLADRGAAATVLGNHDLTLIAGARG
LKEIKEKDRTQDVIDAVDGDDLIDWLRKQPLCLFPNEQTILTHAGVPCIWDAQKTAALAKEVEAVLAHDDLSVLDAFLAE
MYGSKPDLWTDDLTGNERLRCITNYLTRMRLTNAEGALEFSFKDTLDAPMPEGYLPWFEFPSKAAQTHQIFFGHWAALEG
RTISEHIQNVDGGCVWGKNLIAYRLEDQQAFSVSNPVM

Specific function: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP [H]

COG id: COG0639

COG function: function code T; Diadenosine tetraphosphatase and related serine/threonine protein phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Ap4A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1786234, Length=269, Percent_Identity=43.8661710037175, Blast_Score=223, Evalue=2e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004617
- InterPro:   IPR004843 [H]

Pfam domain/function: PF00149 Metallophos [H]

EC number: =3.6.1.41 [H]

Molecular weight: Translated: 31266; Mature: 31135

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKRYNYIIGDVQGCFEALKALLKEIRFDPDQDFIWFAGDLVARGENSIGALRFIKKLAD
CCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCCCCCHHHHHHHHHHHC
RGAAATVLGNHDLTLIAGARGLKEIKEKDRTQDVIDAVDGDDLIDWLRKQPLCLFPNEQT
CCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCE
ILTHAGVPCIWDAQKTAALAKEVEAVLAHDDLSVLDAFLAEMYGSKPDLWTDDLTGNERL
EEEECCCCEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RCITNYLTRMRLTNAEGALEFSFKDTLDAPMPEGYLPWFEFPSKAAQTHQIFFGHWAALE
HHHHHHHHHHHCCCCCCCEEEEHHHCCCCCCCCCCCCHHHCCCHHHHHHHHEEEEEHHCC
GRTISEHIQNVDGGCVWGKNLIAYRLEDQQAFSVSNPVM
CCCHHHHHCCCCCCEEECCCEEEEEECCCHHHCCCCCCC
>Mature Secondary Structure 
TKRYNYIIGDVQGCFEALKALLKEIRFDPDQDFIWFAGDLVARGENSIGALRFIKKLAD
CCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCCCCCHHHHHHHHHHHC
RGAAATVLGNHDLTLIAGARGLKEIKEKDRTQDVIDAVDGDDLIDWLRKQPLCLFPNEQT
CCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCCCCE
ILTHAGVPCIWDAQKTAALAKEVEAVLAHDDLSVLDAFLAEMYGSKPDLWTDDLTGNERL
EEEECCCCEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RCITNYLTRMRLTNAEGALEFSFKDTLDAPMPEGYLPWFEFPSKAAQTHQIFFGHWAALE
HHHHHHHHHHHCCCCCCCEEEEHHHCCCCCCCCCCCCHHHCCCHHHHHHHHEEEEEHHCC
GRTISEHIQNVDGGCVWGKNLIAYRLEDQQAFSVSNPVM
CCCHHHHHCCCCCCEEECCCEEEEEECCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA