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The map label for this gene is ilvA [H]

Identifier: 213157809

GI number: 213157809

Start: 3391207

End: 3392442

Strand: Reverse

Name: ilvA [H]

Synonym: AB57_3292

Alternate gene names: 213157809

Gene position: 3392442-3391207 (Counterclockwise)

Preceding gene: 213157810

Following gene: 213157808

Centisome position: 83.75

GC content: 42.48

Gene sequence:

>1236_bases
ATGATTCAGCAACAGGTAAAAAATGAGTTTCCAACATTAGAAGATATACATGCCGCTGCAGAGCGTTTAGATGGTTTAGT
TGTTAAAACACCTTTTGTTTTTTCAGAAACCATTTCTAAAACCTTAGGGGCTGAAATGTGGCTGAAATTTGAGAATCTAC
AGTTTACGGCTTCGTTTAAAGAAAGGGGCGCACTAAATAAACTTTTGAGCTTATCTGAACAAGAAAAACAACATGGTGTA
ATTGCAGCTTCAGCTGGTAATCATGCGCAAGGGGTCGCTTATCATGCACAGCGCACAGGAGTCACGGCAACTATTGTTAT
GCCAAAATCGACACCCAATGTGAAGGTGCAACGAGTACGTGAATACGGTGCGCGTGTTATTTTGCATGGCCAAGACTTTT
CGGAAGCTGCTGCTGAAATGCACCGTGTGGCACAAGAAGAATCTTTAACCATTATTCATCCATTTGATGACGCTGAAATT
ATTGCGGGTCAAGGTACTATCGCGCTCGAAATGCTGGAAGCTGTTCCTGATTTAGATATCTTGGTCGTACCTATTGGAGG
TGGTGGTCTCATTTCTGGTATTGCGATTGCTGCAAAATCAATAAATCCTAAAATCAAGATTATTGGAGTTCAGTCGGTTG
TTTATCCAAGTATGGCGAAACTGCTTTGTAACTATCAACTCGCGGTTTCAATGGGTTCAACGGTAGCTGAAGGTATTGCT
GTTAAAACTCCGGGCGAGCTGACCACACAAATTGCTAAGCATTTTGTAGATGATATTGTGGTAGTCACTGAAGATATGAT
TGAAGAAGCGATTGCGCTATTACTCAACATTGAAAAAACAGTATGTGAAGGGGCTGGCGCGACTGGAATTGCTGCAATTA
TGTCTCGTCCCGATCTATTTTTAGGCCATAAAGTTGGTGTGGTGTTATCTGGTGGCAATATTGATACACGCGTAATGGTT
TCAGTATTACAGCGTCACTTAACGCGTACTGGCCGTATGGTTCGTATTCGCGTTGAATTACCAGATAATCCGGGTGCCTT
GGCGCGTCTAACAGCAATTATTGCGGAGCAGGGCGGTAATATTTACGAACTTCGACATGAACGCTTTGCCGCAACAAGCC
GTGCTAAAGAAAGTGCGGTGAGTGTCGATATTGAACTAAAAAGCGCTCCAGATCTGGAACCATTAATTCAGGCTATGCAA
CTTGAAGGCTATATTGTTCGTAAAGAAGAGATTTAA

Upstream 100 bases:

>100_bases
AGTGGAGCTATGCTGAAAACTACTCATGACACATATGAGATATTCATGCTATTTTTCAAAAAAATAATTGATTTGTAACA
TATTGAGGCCAGCTACTTAG

Downstream 100 bases:

>100_bases
ACGTACATATGGCTGTGATATAAAAACTGTATATGGCTCTTAGGGGAGCCATATACAAAGCAATTTAAACGGATTAAATT
GCATAAAGGGATGAATTTAC

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MIQQQVKNEFPTLEDIHAAAERLDGLVVKTPFVFSETISKTLGAEMWLKFENLQFTASFKERGALNKLLSLSEQEKQHGV
IAASAGNHAQGVAYHAQRTGVTATIVMPKSTPNVKVQRVREYGARVILHGQDFSEAAAEMHRVAQEESLTIIHPFDDAEI
IAGQGTIALEMLEAVPDLDILVVPIGGGGLISGIAIAAKSINPKIKIIGVQSVVYPSMAKLLCNYQLAVSMGSTVAEGIA
VKTPGELTTQIAKHFVDDIVVVTEDMIEEAIALLLNIEKTVCEGAGATGIAAIMSRPDLFLGHKVGVVLSGGNIDTRVMV
SVLQRHLTRTGRMVRIRVELPDNPGALARLTAIIAEQGGNIYELRHERFAATSRAKESAVSVDIELKSAPDLEPLIQAMQ
LEGYIVRKEEI

Sequences:

>Translated_411_residues
MIQQQVKNEFPTLEDIHAAAERLDGLVVKTPFVFSETISKTLGAEMWLKFENLQFTASFKERGALNKLLSLSEQEKQHGV
IAASAGNHAQGVAYHAQRTGVTATIVMPKSTPNVKVQRVREYGARVILHGQDFSEAAAEMHRVAQEESLTIIHPFDDAEI
IAGQGTIALEMLEAVPDLDILVVPIGGGGLISGIAIAAKSINPKIKIIGVQSVVYPSMAKLLCNYQLAVSMGSTVAEGIA
VKTPGELTTQIAKHFVDDIVVVTEDMIEEAIALLLNIEKTVCEGAGATGIAAIMSRPDLFLGHKVGVVLSGGNIDTRVMV
SVLQRHLTRTGRMVRIRVELPDNPGALARLTAIIAEQGGNIYELRHERFAATSRAKESAVSVDIELKSAPDLEPLIQAMQ
LEGYIVRKEEI
>Mature_411_residues
MIQQQVKNEFPTLEDIHAAAERLDGLVVKTPFVFSETISKTLGAEMWLKFENLQFTASFKERGALNKLLSLSEQEKQHGV
IAASAGNHAQGVAYHAQRTGVTATIVMPKSTPNVKVQRVREYGARVILHGQDFSEAAAEMHRVAQEESLTIIHPFDDAEI
IAGQGTIALEMLEAVPDLDILVVPIGGGGLISGIAIAAKSINPKIKIIGVQSVVYPSMAKLLCNYQLAVSMGSTVAEGIA
VKTPGELTTQIAKHFVDDIVVVTEDMIEEAIALLLNIEKTVCEGAGATGIAAIMSRPDLFLGHKVGVVLSGGNIDTRVMV
SVLQRHLTRTGRMVRIRVELPDNPGALARLTAIIAEQGGNIYELRHERFAATSRAKESAVSVDIELKSAPDLEPLIQAMQ
LEGYIVRKEEI

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=301, Percent_Identity=35.2159468438538, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI19923959, Length=144, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33469958, Length=151, Percent_Identity=35.0993377483444, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1789505, Length=306, Percent_Identity=43.4640522875817, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1790207, Length=381, Percent_Identity=35.1706036745407, Blast_Score=188, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI71991565, Length=395, Percent_Identity=41.5189873417722, Blast_Score=247, Evalue=9e-66,
Organism=Caenorhabditis elegans, GI17537387, Length=377, Percent_Identity=37.6657824933687, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17508781, Length=319, Percent_Identity=30.4075235109718, Blast_Score=148, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6320930, Length=353, Percent_Identity=37.3937677053824, Blast_Score=189, Evalue=9e-49,
Organism=Saccharomyces cerevisiae, GI6322631, Length=315, Percent_Identity=37.4603174603175, Blast_Score=181, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6319788, Length=189, Percent_Identity=29.6296296296296, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI21355833, Length=359, Percent_Identity=44.8467966573816, Blast_Score=233, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24645328, Length=264, Percent_Identity=42.8030303030303, Blast_Score=153, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 44363; Mature: 44363

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQQQVKNEFPTLEDIHAAAERLDGLVVKTPFVFSETISKTLGAEMWLKFENLQFTASFK
CCCHHHHHCCCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHCHHHEEEEECEEEEECHH
ERGALNKLLSLSEQEKQHGVIAASAGNHAQGVAYHAQRTGVTATIVMPKSTPNVKVQRVR
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHH
EYGARVILHGQDFSEAAAEMHRVAQEESLTIIHPFDDAEIIAGQGTIALEMLEAVPDLDI
HHCCEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHCCCCCE
LVVPIGGGGLISGIAIAAKSINPKIKIIGVQSVVYPSMAKLLCNYQLAVSMGSTVAEGIA
EEEEECCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCHHHEEECCCHHHCCEE
VKTPGELTTQIAKHFVDDIVVVTEDMIEEAIALLLNIEKTVCEGAGATGIAAIMSRPDLF
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEE
LGHKVGVVLSGGNIDTRVMVSVLQRHLTRTGRMVRIRVELPDNPGALARLTAIIAEQGGN
ECCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCC
IYELRHERFAATSRAKESAVSVDIELKSAPDLEPLIQAMQLEGYIVRKEEI
EEEEHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHCCCEEEEECCC
>Mature Secondary Structure
MIQQQVKNEFPTLEDIHAAAERLDGLVVKTPFVFSETISKTLGAEMWLKFENLQFTASFK
CCCHHHHHCCCCHHHHHHHHHHHCCEEEECCHHHHHHHHHHHCHHHEEEEECEEEEECHH
ERGALNKLLSLSEQEKQHGVIAASAGNHAQGVAYHAQRTGVTATIVMPKSTPNVKVQRVR
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHHHHH
EYGARVILHGQDFSEAAAEMHRVAQEESLTIIHPFDDAEIIAGQGTIALEMLEAVPDLDI
HHCCEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHCCCCCE
LVVPIGGGGLISGIAIAAKSINPKIKIIGVQSVVYPSMAKLLCNYQLAVSMGSTVAEGIA
EEEEECCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHCHHHEEECCCHHHCCEE
VKTPGELTTQIAKHFVDDIVVVTEDMIEEAIALLLNIEKTVCEGAGATGIAAIMSRPDLF
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEE
LGHKVGVVLSGGNIDTRVMVSVLQRHLTRTGRMVRIRVELPDNPGALARLTAIIAEQGGN
ECCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCC
IYELRHERFAATSRAKESAVSVDIELKSAPDLEPLIQAMQLEGYIVRKEEI
EEEEHHHHHHHHHHHHHCEEEEEEEECCCCCHHHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA