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The map label for this gene is sdhB [H]

Identifier: 213157650

GI number: 213157650

Start: 3252596

End: 3253306

Strand: Reverse

Name: sdhB [H]

Synonym: AB57_3128

Alternate gene names: 213157650

Gene position: 3253306-3252596 (Counterclockwise)

Preceding gene: 213157651

Following gene: 213157649

Centisome position: 80.32

GC content: 39.94

Gene sequence:

>711_bases
ATGAGTAGAGGTACTCGTACATTCGAAATCTACCGCTATGATCCTGATAAGGATAAAGCGCCGTACATGCAAACTTTCAA
GCTTGAATTGACTGATAAGCACCGTATGTTGCTTGATGCATTGCTTGCTTTGAAGGTTCAAGACGAAACATTAACATTCC
GTCGTTCTTGCCGTGAAGGTATTTGTGGTTCTGATGGTGTGAATATCAATGGTAAAAATGGTTTGGCTTGCTTGCAAAAC
CTTAACGATTTACCAGAGAAAATTGTAATTCGTCCATTACCTGGTTTGCCGGTTGTTAAAGATTTGGTTGTTGATATGAA
CCAATTCTATGATCAGTATGACAAAATTCAGCCATTCTTGATCAATAACCAACCTGCTCCACCTAAAGAGCGTTTGCAAT
CTCCTGAAGAGCGTGAACACTTAAATGGTTTGTATGAGTGTATTCTTTGTGCATGTTGTTCAACTTCATGCCCATCATTC
TGGTGGAACCCTGATAAATTCTTGGGTCCTTCAGCGTTGTTGAATGCATATCGTTTTATTATCGACTCTCGTGATACTGC
AACTGCAGAACGTTTGGCTCGTCTTGACGATCCGTTCAGTTTGTTCCGTTGTAAAGGTATTATGAATTGTGTGTCAGTAT
GCCCTAAAGGTTTGAATCCAACAAAAGCAATCGGTCATATCCGTAATATGTTGTTAGATCAAGCGGGTTAA

Upstream 100 bases:

>100_bases
CATCAGATAACCGTTTGGAATATAAGCCAGTGCGCTTCAAGCCGTTAACTGTTGATCCAATTCCACCAGCACCACGTACA
TTCTAATCGGGAGTATAAAG

Downstream 100 bases:

>100_bases
TTCTGCGCAAATAGAGAACGCACATCCTTGATGTGCGTTTTTTTTTAATTTTATAATACGTGTCTTATACTTTAGTCGGT
AAAAGAGGGGTTTTTATATA

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSRGTRTFEIYRYDPDKDKAPYMQTFKLELTDKHRMLLDALLALKVQDETLTFRRSCREGICGSDGVNINGKNGLACLQN
LNDLPEKIVIRPLPGLPVVKDLVVDMNQFYDQYDKIQPFLINNQPAPPKERLQSPEEREHLNGLYECILCACCSTSCPSF
WWNPDKFLGPSALLNAYRFIIDSRDTATAERLARLDDPFSLFRCKGIMNCVSVCPKGLNPTKAIGHIRNMLLDQAG

Sequences:

>Translated_236_residues
MSRGTRTFEIYRYDPDKDKAPYMQTFKLELTDKHRMLLDALLALKVQDETLTFRRSCREGICGSDGVNINGKNGLACLQN
LNDLPEKIVIRPLPGLPVVKDLVVDMNQFYDQYDKIQPFLINNQPAPPKERLQSPEEREHLNGLYECILCACCSTSCPSF
WWNPDKFLGPSALLNAYRFIIDSRDTATAERLARLDDPFSLFRCKGIMNCVSVCPKGLNPTKAIGHIRNMLLDQAG
>Mature_235_residues
SRGTRTFEIYRYDPDKDKAPYMQTFKLELTDKHRMLLDALLALKVQDETLTFRRSCREGICGSDGVNINGKNGLACLQNL
NDLPEKIVIRPLPGLPVVKDLVVDMNQFYDQYDKIQPFLINNQPAPPKERLQSPEEREHLNGLYECILCACCSTSCPSFW
WNPDKFLGPSALLNAYRFIIDSRDTATAERLARLDDPFSLFRCKGIMNCVSVCPKGLNPTKAIGHIRNMLLDQAG

Specific function: Two distinct, membrane-bound, FAD-containing enzymes are responsible for the catalysis of fumarate and succinate interconversion; the fumarate reductase is used in anaerobic growth, and the succinate dehydrogenase is used in aerobic growth [H]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=232, Percent_Identity=57.7586206896552, Blast_Score=269, Evalue=2e-72,
Organism=Escherichia coli, GI1786943, Length=232, Percent_Identity=68.5344827586207, Blast_Score=330, Evalue=5e-92,
Organism=Escherichia coli, GI1790596, Length=219, Percent_Identity=35.6164383561644, Blast_Score=141, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17533915, Length=231, Percent_Identity=55.4112554112554, Blast_Score=257, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6322987, Length=230, Percent_Identity=53.9130434782609, Blast_Score=253, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17137106, Length=233, Percent_Identity=55.3648068669528, Blast_Score=267, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24643156, Length=232, Percent_Identity=53.8793103448276, Blast_Score=249, Evalue=9e-67,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26804; Mature: 26673

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRGTRTFEIYRYDPDKDKAPYMQTFKLELTDKHRMLLDALLALKVQDETLTFRRSCREG
CCCCCEEEEEEEECCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
ICGSDGVNINGKNGLACLQNLNDLPEKIVIRPLPGLPVVKDLVVDMNQFYDQYDKIQPFL
CCCCCCCEECCCCHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
INNQPAPPKERLQSPEEREHLNGLYECILCACCSTSCPSFWWNPDKFLGPSALLNAYRFI
ECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHH
IDSRDTATAERLARLDDPFSLFRCKGIMNCVSVCPKGLNPTKAIGHIRNMLLDQAG
HCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRGTRTFEIYRYDPDKDKAPYMQTFKLELTDKHRMLLDALLALKVQDETLTFRRSCREG
CCCCEEEEEEEECCCCCCCCCEEEEEEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
ICGSDGVNINGKNGLACLQNLNDLPEKIVIRPLPGLPVVKDLVVDMNQFYDQYDKIQPFL
CCCCCCCEECCCCHHHHHHHHHHCCHHHEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEE
INNQPAPPKERLQSPEEREHLNGLYECILCACCSTSCPSFWWNPDKFLGPSALLNAYRFI
ECCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHHHHHHHHHH
IDSRDTATAERLARLDDPFSLFRCKGIMNCVSVCPKGLNPTKAIGHIRNMLLDQAG
HCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6388571; 8905232; 9278503; 6376123; 9298646 [H]