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The map label for this gene is cobP [H]

Identifier: 213157201

GI number: 213157201

Start: 1975339

End: 1975857

Strand: Direct

Name: cobP [H]

Synonym: AB57_1884

Alternate gene names: 213157201

Gene position: 1975339-1975857 (Clockwise)

Preceding gene: 213157200

Following gene: 213157202

Centisome position: 48.77

GC content: 39.31

Gene sequence:

>519_bases
ATGTTGCAATTGATTTTAGGTGGTGCCCGTTCTGGCAAAAGCCGATTGGCTGAACAAACGGCCATATCTATGCAATTAGC
TGTCACTTATGTGGCTACGGCACAAGCGCTTGATCCAGAAATGCAAAGCCGAATCGTCCATCATCAAAATCAGCGTCCTG
CTCACTGGTCTTTAGTTGAAGAACCATTATTTTTAGCAAAAACTCTGCAAGAAATTGATCGACCTAACCAAATTATTCTG
GTGGATTGTTTAACACTTTGGCTAACCAATTTGTTACTTTTAGAAGATCAAAATATTCAACAATTTGAGTGTGAGCAGCT
GTTAAGAGTTTTACCTACACTTCAGTCAGAAATTATTTTAGTAAGTAATGAAACGGGTTTAGGCGTTGTGCCACTTGGTG
AAATTAGCCGCCGTTTTGTCGATGAAGCAGGAAGGCTACATCAGGCTTTAGGACAAATTGCAGATAAAGTTGTGTTTTGT
GTGGCTGGTTTTCCAATGATTTTAAAAGGTGAGAAATAA

Upstream 100 bases:

>100_bases
AATTTGATCTTAAAGTTGAGCATTTAAGCTTTGGCTATTATCAAGCTCAAATTTTACAAGGTCAGCTGTATCCGTATCAG
CATTTGTTTTTAGGTGATTC

Downstream 100 bases:

>100_bases
AAATGAACTGGTGGTTACAATCTGTGCAGCAACCTAATTTAGATACAAAACAACAAGCTGAGCAACATCAACTCCAACTT
ACCAAACCTACAGGTGCTTT

Product: bifunctional adenosylcobalamin biosynthesis protein CobP

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MLQLILGGARSGKSRLAEQTAISMQLAVTYVATAQALDPEMQSRIVHHQNQRPAHWSLVEEPLFLAKTLQEIDRPNQIIL
VDCLTLWLTNLLLLEDQNIQQFECEQLLRVLPTLQSEIILVSNETGLGVVPLGEISRRFVDEAGRLHQALGQIADKVVFC
VAGFPMILKGEK

Sequences:

>Translated_172_residues
MLQLILGGARSGKSRLAEQTAISMQLAVTYVATAQALDPEMQSRIVHHQNQRPAHWSLVEEPLFLAKTLQEIDRPNQIIL
VDCLTLWLTNLLLLEDQNIQQFECEQLLRVLPTLQSEIILVSNETGLGVVPLGEISRRFVDEAGRLHQALGQIADKVVFC
VAGFPMILKGEK
>Mature_172_residues
MLQLILGGARSGKSRLAEQTAISMQLAVTYVATAQALDPEMQSRIVHHQNQRPAHWSLVEEPLFLAKTLQEIDRPNQIIL
VDCLTLWLTNLLLLEDQNIQQFECEQLLRVLPTLQSEIILVSNETGLGVVPLGEISRRFVDEAGRLHQALGQIADKVVFC
VAGFPMILKGEK

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=182, Percent_Identity=37.3626373626374, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 19204; Mature: 19204

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLILGGARSGKSRLAEQTAISMQLAVTYVATAQALDPEMQSRIVHHQNQRPAHWSLVE
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHH
EPLFLAKTLQEIDRPNQIILVDCLTLWLTNLLLLEDQNIQQFECEQLLRVLPTLQSEIIL
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEE
VSNETGLGVVPLGEISRRFVDEAGRLHQALGQIADKVVFCVAGFPMILKGEK
EECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
>Mature Secondary Structure
MLQLILGGARSGKSRLAEQTAISMQLAVTYVATAQALDPEMQSRIVHHQNQRPAHWSLVE
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHH
EPLFLAKTLQEIDRPNQIILVDCLTLWLTNLLLLEDQNIQQFECEQLLRVLPTLQSEIIL
HHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEE
VSNETGLGVVPLGEISRRFVDEAGRLHQALGQIADKVVFCVAGFPMILKGEK
EECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]