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The map label for this gene is tadA [H]

Identifier: 213157131

GI number: 213157131

Start: 1898012

End: 1898488

Strand: Direct

Name: tadA [H]

Synonym: AB57_1814

Alternate gene names: 213157131

Gene position: 1898012-1898488 (Clockwise)

Preceding gene: 213157130

Following gene: 213157132

Centisome position: 46.86

GC content: 38.57

Gene sequence:

>477_bases
ATGCAGCTTGCTTACGAGCAAGCTGAATTAGCAGCCAAGCAGGGGGAAATTCCTGTAGGAGCTGTAATCGTGAGCCAAAA
TAAGTTAATTGGAGCTGGTTTTAATGCTCCAATTGGTTTATCTGATCCTACGGCTCATGCAGAAATTCAAGCTATTCGTG
CGGCTTGTGAGTCATTGAAAAATTATCGTTTACCTGAAGATGCGACTTTGTACGTTACGCTTGAGCCGTGCACAATGTGT
GTGGGAGCATTAGTACATGCAAGAATTAAACATGTCGTATTTGGAACAACAGAACCTAAAGCTGGCTCACTCGTGAGTGC
ACGTCAATTATTAGAAAATGGTTATTACAACCATAAATTTACTTTTGAGCATGGATGTTTACATGAAAAATGTGCTCAAC
AGTTAAGTCTTTTTTTTAAGCAAAGACGTGAACAAAAGAAACAAGAGAAACAACAAAAAACGTCCTTAAATGATTAA

Upstream 100 bases:

>100_bases
TGATCCACCGATCACGACGATTGATAGCTGGAATGCATTACTTAGACAATATGGTGTAGTGTCATAATCAATAATGTCTA
AATTTAGTGATGAGTATTGG

Downstream 100 bases:

>100_bases
AAAATGTCATGACGTTATGGCACACTAACGCCGTTTCATTGACATGATTTATTTAAATAAGGAACTTTCATGCGTAATGT
AATTACTATACAAAAAGAAT

Product: tRNA-specific adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MQLAYEQAELAAKQGEIPVGAVIVSQNKLIGAGFNAPIGLSDPTAHAEIQAIRAACESLKNYRLPEDATLYVTLEPCTMC
VGALVHARIKHVVFGTTEPKAGSLVSARQLLENGYYNHKFTFEHGCLHEKCAQQLSLFFKQRREQKKQEKQQKTSLND

Sequences:

>Translated_158_residues
MQLAYEQAELAAKQGEIPVGAVIVSQNKLIGAGFNAPIGLSDPTAHAEIQAIRAACESLKNYRLPEDATLYVTLEPCTMC
VGALVHARIKHVVFGTTEPKAGSLVSARQLLENGYYNHKFTFEHGCLHEKCAQQLSLFFKQRREQKKQEKQQKTSLND
>Mature_158_residues
MQLAYEQAELAAKQGEIPVGAVIVSQNKLIGAGFNAPIGLSDPTAHAEIQAIRAACESLKNYRLPEDATLYVTLEPCTMC
VGALVHARIKHVVFGTTEPKAGSLVSARQLLENGYYNHKFTFEHGCLHEKCAQQLSLFFKQRREQKKQEKQQKTSLND

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=160, Percent_Identity=29.375, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI145693172, Length=157, Percent_Identity=47.1337579617834, Blast_Score=150, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17554608, Length=121, Percent_Identity=37.1900826446281, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17541138, Length=113, Percent_Identity=36.283185840708, Blast_Score=71, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17555996, Length=104, Percent_Identity=35.5769230769231, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325319, Length=97, Percent_Identity=35.0515463917526, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17513; Mature: 17513

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLAYEQAELAAKQGEIPVGAVIVSQNKLIGAGFNAPIGLSDPTAHAEIQAIRAACESLK
CCCCHHHHHHHHHCCCCCEEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NYRLPEDATLYVTLEPCTMCVGALVHARIKHVVFGTTEPKAGSLVSARQLLENGYYNHKF
HCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEE
TFEHGCLHEKCAQQLSLFFKQRREQKKQEKQQKTSLND
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQLAYEQAELAAKQGEIPVGAVIVSQNKLIGAGFNAPIGLSDPTAHAEIQAIRAACESLK
CCCCHHHHHHHHHCCCCCEEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHH
NYRLPEDATLYVTLEPCTMCVGALVHARIKHVVFGTTEPKAGSLVSARQLLENGYYNHKF
HCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEE
TFEHGCLHEKCAQQLSLFFKQRREQKKQEKQQKTSLND
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]