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The map label for this gene is gltK [H]

Identifier: 213157047

GI number: 213157047

Start: 1817477

End: 1818154

Strand: Direct

Name: gltK [H]

Synonym: AB57_1727

Alternate gene names: 213157047

Gene position: 1817477-1818154 (Clockwise)

Preceding gene: 213157046

Following gene: 213157048

Centisome position: 44.87

GC content: 38.94

Gene sequence:

>678_bases
ATGGATTTTTCTCTATTGCATAATCCTGATGTTATTGCGGCATTAAAAGAAGGATTTATTTTTACACTTACCGTAACCGT
GCTTGCAATGATGGGGGGCATCCTCATTGGAACTCCTTTGGCAATGATGCGTTTATCCAACAACGCCCTTGCAAGTAACT
TTGCCAAGTTCTATGTAGATTTATTCCGTGGTATCCCATTAATTCAGGTTATTTTTATTTTTTATTTCTTGTTGCCAAAG
ATATTTGAGTTTCAATCAGATACGTATTGGGGGCCATTATTTTCCAGCGTTGTGACTTTTGCCATTTTTGAAGCTGCGTT
TTTCTCGGAAATTGTACGTTCGGGTATTCAGTCTATTTCAAAAGGGCAAGTCAATGCAGGCTACGCTTTAGGTTTTACCT
ATGGACAATCCATGCGTTATGTGGTGTTACCGCAGGCCTTTCGCAATATGCTTCCGGTATTACTTACTCAAACCATCATT
TTATTTCAGGATGTGTCATTAGTTTATGTCATTAGTGCACCAGACTTCTTAGGTCGTGCAGATACTTTGGCTAATACCTA
TGGTCCTGAAACGAAAGCAACATTCTATTTAATCGTCGCTGTGGTGTATTTCTGTAGCTCGTTTGTGCTATCGCAATTAG
TCAAACGTTTGCAGAAAAAAATTGCCATCATTCGCTAA

Upstream 100 bases:

>100_bases
CACCTGTCTATTTAATCATTACATACACCATTAAATTTATAATGGCATGGATTGAAAAACGCATGGCTGTACCAGGTTTA
GGCTCGGGAGGAAAATAATT

Downstream 100 bases:

>100_bases
TTGGAGATTTTAAATGCCAATGATAGACATCCAACATATCTCTAAATGGTATGGTGATTTTCAGGTTTTAACAGATTGCA
CGACGAGTATTGAAAAAGGT

Product: glutamate/aspartate transport system permease protein GltK

Products: ADP; phosphate; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MDFSLLHNPDVIAALKEGFIFTLTVTVLAMMGGILIGTPLAMMRLSNNALASNFAKFYVDLFRGIPLIQVIFIFYFLLPK
IFEFQSDTYWGPLFSSVVTFAIFEAAFFSEIVRSGIQSISKGQVNAGYALGFTYGQSMRYVVLPQAFRNMLPVLLTQTII
LFQDVSLVYVISAPDFLGRADTLANTYGPETKATFYLIVAVVYFCSSFVLSQLVKRLQKKIAIIR

Sequences:

>Translated_225_residues
MDFSLLHNPDVIAALKEGFIFTLTVTVLAMMGGILIGTPLAMMRLSNNALASNFAKFYVDLFRGIPLIQVIFIFYFLLPK
IFEFQSDTYWGPLFSSVVTFAIFEAAFFSEIVRSGIQSISKGQVNAGYALGFTYGQSMRYVVLPQAFRNMLPVLLTQTII
LFQDVSLVYVISAPDFLGRADTLANTYGPETKATFYLIVAVVYFCSSFVLSQLVKRLQKKIAIIR
>Mature_225_residues
MDFSLLHNPDVIAALKEGFIFTLTVTVLAMMGGILIGTPLAMMRLSNNALASNFAKFYVDLFRGIPLIQVIFIFYFLLPK
IFEFQSDTYWGPLFSSVVTFAIFEAAFFSEIVRSGIQSISKGQVNAGYALGFTYGQSMRYVVLPQAFRNMLPVLLTQTII
LFQDVSLVYVISAPDFLGRADTLANTYGPETKATFYLIVAVVYFCSSFVLSQLVKRLQKKIAIIR

Specific function: Part of the binding-protein-dependent transport system for aspartate/glutamate; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786873, Length=214, Percent_Identity=47.196261682243, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI1787030, Length=214, Percent_Identity=35.5140186915888, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788226, Length=212, Percent_Identity=34.4339622641509, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1786874, Length=219, Percent_Identity=28.310502283105, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI87082239, Length=206, Percent_Identity=29.126213592233, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1788645, Length=209, Percent_Identity=29.1866028708134, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788646, Length=215, Percent_Identity=25.5813953488372, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1787087, Length=181, Percent_Identity=24.3093922651934, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994930, Length=131, Percent_Identity=32.0610687022901, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25161; Mature: 25161

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSLLHNPDVIAALKEGFIFTLTVTVLAMMGGILIGTPLAMMRLSNNALASNFAKFYVD
CCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHH
LFRGIPLIQVIFIFYFLLPKIFEFQSDTYWGPLFSSVVTFAIFEAAFFSEIVRSGIQSIS
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGQVNAGYALGFTYGQSMRYVVLPQAFRNMLPVLLTQTIILFQDVSLVYVISAPDFLGRA
CCCCCCCEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHH
DTLANTYGPETKATFYLIVAVVYFCSSFVLSQLVKRLQKKIAIIR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDFSLLHNPDVIAALKEGFIFTLTVTVLAMMGGILIGTPLAMMRLSNNALASNFAKFYVD
CCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHH
LFRGIPLIQVIFIFYFLLPKIFEFQSDTYWGPLFSSVVTFAIFEAAFFSEIVRSGIQSIS
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KGQVNAGYALGFTYGQSMRYVVLPQAFRNMLPVLLTQTIILFQDVSLVYVISAPDFLGRA
CCCCCCCEEEEEEECCCCEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHH
DTLANTYGPETKATFYLIVAVVYFCSSFVLSQLVKRLQKKIAIIR
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamate [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamate [Periplasm] + H2O = ADP + phosphate + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]