Click here to switch to the map view.

The map label for this gene is gpo [H]

Identifier: 213157023

GI number: 213157023

Start: 1794106

End: 1794591

Strand: Direct

Name: gpo [H]

Synonym: AB57_1701

Alternate gene names: 213157023

Gene position: 1794106-1794591 (Clockwise)

Preceding gene: 213157022

Following gene: 213157024

Centisome position: 44.29

GC content: 36.21

Gene sequence:

>486_bases
ATGAGTAACATTTATCAGTTTGAAGCTGAATTGTTAGAGGGAGATATTAAACAATTCGCTGATTACAAAGGTAAAGTTTT
ATTAATTGTAAATACTGCAAGTAAATGTGGTTTTACTCCACAGTTTGCGGGCCTCGAAAAACTTTATGAAAAGTATAAAG
ACCAAGGTTTAGAAGTTTTAGGTTTTCCCTGCAATCAGTTTGGTGGGCAAGATCCCGGAAGCAATAAAGAGATAGGTACA
TTCTGCCAGCGTAACTATGGAGTGAAATTCCCTATGTTTGCCAAAGTAGATGTAAAAGGTCCTGAAGCTCATGTGATCTT
TAGATATTTAACCCGTGAAGCAAAAGGAATTTTAGGAAGCAGTACTATTAAATGGAACTTTACCAAGTTTTTAGTTGGTA
AAGATGGTTCGGTTTTAAATCGTTATGCGCCAACAACCAAGCCTGAAGCATTGGAAGCTGATATTGAAAAAGCATTAGCG
AGTTAA

Upstream 100 bases:

>100_bases
TTTTTGAAGATGGACCACAGCCGACAGGTTTGCGCTACTGTGTGAACTCGGCATCATTACAACTGAAAACACAAGAAAAA
AATGATGAGGAAACCTATCC

Downstream 100 bases:

>100_bases
TGGGTTCAATGAACGCTATTCCTCAAACTTTCGAGTTTTGGCAAGATCGGCGAATGCCTTATGTGGAAACCCGAAGGTCT
TGTTTTGGCAGAACATGTTA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSNIYQFEAELLEGDIKQFADYKGKVLLIVNTASKCGFTPQFAGLEKLYEKYKDQGLEVLGFPCNQFGGQDPGSNKEIGT
FCQRNYGVKFPMFAKVDVKGPEAHVIFRYLTREAKGILGSSTIKWNFTKFLVGKDGSVLNRYAPTTKPEALEADIEKALA
S

Sequences:

>Translated_161_residues
MSNIYQFEAELLEGDIKQFADYKGKVLLIVNTASKCGFTPQFAGLEKLYEKYKDQGLEVLGFPCNQFGGQDPGSNKEIGT
FCQRNYGVKFPMFAKVDVKGPEAHVIFRYLTREAKGILGSSTIKWNFTKFLVGKDGSVLNRYAPTTKPEALEADIEKALA
S
>Mature_160_residues
SNIYQFEAELLEGDIKQFADYKGKVLLIVNTASKCGFTPQFAGLEKLYEKYKDQGLEVLGFPCNQFGGQDPGSNKEIGTF
CQRNYGVKFPMFAKVDVKGPEAHVIFRYLTREAKGILGSSTIKWNFTKFLVGKDGSVLNRYAPTTKPEALEADIEKALAS

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=42.3076923076923, Blast_Score=130, Evalue=4e-31,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=42.3076923076923, Blast_Score=130, Evalue=6e-31,
Organism=Homo sapiens, GI15618997, Length=154, Percent_Identity=41.5584415584416, Blast_Score=126, Evalue=9e-30,
Organism=Homo sapiens, GI192455698, Length=156, Percent_Identity=37.1794871794872, Blast_Score=115, Evalue=1e-26,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=42.7480916030534, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI4557629, Length=173, Percent_Identity=39.3063583815029, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI33186887, Length=176, Percent_Identity=35.2272727272727, Blast_Score=91, Evalue=6e-19,
Organism=Homo sapiens, GI6006001, Length=173, Percent_Identity=35.2601156069364, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI41406084, Length=184, Percent_Identity=35.8695652173913, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI32967607, Length=181, Percent_Identity=32.5966850828729, Blast_Score=80, Evalue=7e-16,
Organism=Escherichia coli, GI1788003, Length=157, Percent_Identity=42.0382165605096, Blast_Score=138, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17506887, Length=160, Percent_Identity=45.625, Blast_Score=149, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17535473, Length=162, Percent_Identity=41.9753086419753, Blast_Score=141, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71993584, Length=159, Percent_Identity=37.1069182389937, Blast_Score=118, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI193210707, Length=161, Percent_Identity=39.1304347826087, Blast_Score=113, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI193209493, Length=181, Percent_Identity=30.939226519337, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17550320, Length=181, Percent_Identity=30.3867403314917, Blast_Score=99, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=40.7894736842105, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71993573, Length=94, Percent_Identity=36.1702127659575, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=159, Percent_Identity=50.314465408805, Blast_Score=176, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322228, Length=159, Percent_Identity=51.5723270440252, Blast_Score=171, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6322826, Length=159, Percent_Identity=42.7672955974843, Blast_Score=137, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24656772, Length=160, Percent_Identity=47.5, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24656767, Length=160, Percent_Identity=47.5, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24656777, Length=160, Percent_Identity=47.5, Blast_Score=137, Evalue=4e-33,
Organism=Drosophila melanogaster, GI85726443, Length=149, Percent_Identity=45.6375838926174, Blast_Score=123, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17922; Mature: 17791

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNIYQFEAELLEGDIKQFADYKGKVLLIVNTASKCGFTPQFAGLEKLYEKYKDQGLEVL
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEE
GFPCNQFGGQDPGSNKEIGTFCQRNYGVKFPMFAKVDVKGPEAHVIFRYLTREAKGILGS
ECCHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCC
STIKWNFTKFLVGKDGSVLNRYAPTTKPEALEADIEKALAS
CEEEEEEEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SNIYQFEAELLEGDIKQFADYKGKVLLIVNTASKCGFTPQFAGLEKLYEKYKDQGLEVL
CCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEE
GFPCNQFGGQDPGSNKEIGTFCQRNYGVKFPMFAKVDVKGPEAHVIFRYLTREAKGILGS
ECCHHHCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCC
STIKWNFTKFLVGKDGSVLNRYAPTTKPEALEADIEKALAS
CEEEEEEEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]