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The map label for this gene is msrB

Identifier: 213157022

GI number: 213157022

Start: 1793690

End: 1794109

Strand: Direct

Name: msrB

Synonym: AB57_1700

Alternate gene names: 213157022

Gene position: 1793690-1794109 (Clockwise)

Preceding gene: 213157013

Following gene: 213157023

Centisome position: 44.28

GC content: 42.14

Gene sequence:

>420_bases
ATGGGAAAAGTTAATAAAACAGACCGAGAATGGCAAAGAGAGTTATCACCTGAAGAATATCGGATAACGCGACAAAAGGG
CACTGAACCAGCATTTACGGGGCAATACTGGAATACTAAGCAACATGGCACTTATGTTTGTCGTTGTTGTGGCGCGGAAT
TGTTTTCGTCAGATGCAAAATATGATAGTGGTTGTGGTTGGCCAAGTTTCTTTCGCCCTCTGAATGGAAGCGTTATTGAT
GAACATGAAGATTTAACGCATGGTATGGTCAGAACGGAAATTGTTTGTCATGATTGCGAAGCTCATCTTGGGCATGTTTT
TGAAGATGGACCACAGCCGACAGGTTTGCGCTACTGTGTGAACTCGGCATCATTACAACTGAAAACACAAGAAAAAAATG
ATGAGGAAACCTATCCATGA

Upstream 100 bases:

>100_bases
ACAAATTTTACGTTCAGAGACTAGTGTTTTTTTGATGAATGGCGTAAATATAAAATACGATTATCAATTTATGTTTACAT
CAGAATAAAAGGTGCAGGTC

Downstream 100 bases:

>100_bases
GTAACATTTATCAGTTTGAAGCTGAATTGTTAGAGGGAGATATTAAACAATTCGCTGATTACAAAGGTAAAGTTTTATTA
ATTGTAAATACTGCAAGTAA

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MGKVNKTDREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQHGTYVCRCCGAELFSSDAKYDSGCGWPSFFRPLNGSVID
EHEDLTHGMVRTEIVCHDCEAHLGHVFEDGPQPTGLRYCVNSASLQLKTQEKNDEETYP

Sequences:

>Translated_139_residues
MGKVNKTDREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQHGTYVCRCCGAELFSSDAKYDSGCGWPSFFRPLNGSVID
EHEDLTHGMVRTEIVCHDCEAHLGHVFEDGPQPTGLRYCVNSASLQLKTQEKNDEETYP
>Mature_138_residues
GKVNKTDREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQHGTYVCRCCGAELFSSDAKYDSGCGWPSFFRPLNGSVIDE
HEDLTHGMVRTEIVCHDCEAHLGHVFEDGPQPTGLRYCVNSASLQLKTQEKNDEETYP

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family

Homologues:

Organism=Homo sapiens, GI117606353, Length=129, Percent_Identity=51.1627906976744, Blast_Score=138, Evalue=1e-33,
Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=48.8, Blast_Score=135, Evalue=9e-33,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=48.8, Blast_Score=135, Evalue=9e-33,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=48.8, Blast_Score=135, Evalue=9e-33,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=48.8, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI1788077, Length=126, Percent_Identity=53.968253968254, Blast_Score=144, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17553450, Length=124, Percent_Identity=47.5806451612903, Blast_Score=121, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=124, Percent_Identity=47.5806451612903, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319816, Length=127, Percent_Identity=42.5196850393701, Blast_Score=100, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24645799, Length=126, Percent_Identity=46.8253968253968, Blast_Score=125, Evalue=8e-30,
Organism=Drosophila melanogaster, GI221378664, Length=126, Percent_Identity=46.8253968253968, Blast_Score=125, Evalue=9e-30,
Organism=Drosophila melanogaster, GI45553335, Length=126, Percent_Identity=46.8253968253968, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI21356369, Length=126, Percent_Identity=46.8253968253968, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221378662, Length=146, Percent_Identity=43.8356164383562, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24645801, Length=137, Percent_Identity=43.7956204379562, Blast_Score=121, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24645804, Length=137, Percent_Identity=43.7956204379562, Blast_Score=121, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSRB_ACIB3 (B7H3X2)

Other databases:

- EMBL:   CP001172
- RefSeq:   YP_002325920.1
- ProteinModelPortal:   B7H3X2
- SMR:   B7H3X2
- GeneID:   7057983
- GenomeReviews:   CP001172_GR
- KEGG:   abb:ABBFA_002018
- HOGENOM:   HBG715255
- OMA:   EVRCNHC
- ProtClustDB:   CLSK707445
- HAMAP:   MF_01400
- InterPro:   IPR002579
- InterPro:   IPR011057
- Gene3D:   G3DSA:2.170.150.20
- TIGRFAMs:   TIGR00357

Pfam domain/function: PF01641 SelR; SSF51316 Mss4_like

EC number: =1.8.4.12

Molecular weight: Translated: 15909; Mature: 15777

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVNKTDREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQHGTYVCRCCGAELFSSDAK
CCCCCCCHHHHHHCCCCHHEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHCHHHHCCCCC
YDSGCGWPSFFRPLNGSVIDEHEDLTHGMVRTEIVCHDCEAHLGHVFEDGPQPTGLRYCV
CCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHCHHHCCCCCCCCHHEEE
NSASLQLKTQEKNDEETYP
CCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
GKVNKTDREWQRELSPEEYRITRQKGTEPAFTGQYWNTKQHGTYVCRCCGAELFSSDAK
CCCCCCHHHHHHCCCCHHEEEECCCCCCCCCCCCCCCCCCCCCEEHHHHCHHHHCCCCC
YDSGCGWPSFFRPLNGSVIDEHEDLTHGMVRTEIVCHDCEAHLGHVFEDGPQPTGLRYCV
CCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHCHHHCCCCCCCCHHEEE
NSASLQLKTQEKNDEETYP
CCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA