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The map label for this gene is arsR [H]

Identifier: 213157008

GI number: 213157008

Start: 1774443

End: 1774772

Strand: Direct

Name: arsR [H]

Synonym: AB57_1686

Alternate gene names: 213157008

Gene position: 1774443-1774772 (Clockwise)

Preceding gene: 213157006

Following gene: 213157009

Centisome position: 43.81

GC content: 35.15

Gene sequence:

>330_bases
ATGATCAATCAAGTCGATTTCTTTAAATGTCTATCTGACCAAACTCGGTTAAATATTCTTAAATTAGTTCTAAATAAACA
AAATATTTGTGTTTGTGAGCTAACAGAACAGCTTGAGTTGAGCCAACCGAAAATCTCCAGACACTTGGCCTTATTAAGAA
CTCATGGCGTATTACTGGATGAAAGAAAAGGACAGTGGGTTTATTACAGCTTAAATCCGGATTTACCTGTTTGGGCTTTA
GATATTCTAAAGGTGATAGAAAATGACGAGAGTGGGACAAAAGTAAAACAACAAGATCAGTCTTTCATCACGACAACGTG
TTGTGATTAA

Upstream 100 bases:

>100_bases
TCACTAGCTCAGTCATGACAAATTTATCGATGAATTAAGATATTGCATTTATATATGGATATCCGTATATTTGCAATAAC
GAATATATTTTGTTGAAGAT

Downstream 100 bases:

>100_bases
TCTTCCTAGATTTCCGTCTTTAAAATTTAGATTTTCTTAGCATAAGTGCATAAGTCATTTGTGTGTATTGAGCAAAATTA
ATCAATTCTTTCTTCGAGTA

Product: transcriptional regulator, ArsR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MINQVDFFKCLSDQTRLNILKLVLNKQNICVCELTEQLELSQPKISRHLALLRTHGVLLDERKGQWVYYSLNPDLPVWAL
DILKVIENDESGTKVKQQDQSFITTTCCD

Sequences:

>Translated_109_residues
MINQVDFFKCLSDQTRLNILKLVLNKQNICVCELTEQLELSQPKISRHLALLRTHGVLLDERKGQWVYYSLNPDLPVWAL
DILKVIENDESGTKVKQQDQSFITTTCCD
>Mature_109_residues
MINQVDFFKCLSDQTRLNILKLVLNKQNICVCELTEQLELSQPKISRHLALLRTHGVLLDERKGQWVYYSLNPDLPVWAL
DILKVIENDESGTKVKQQDQSFITTTCCD

Specific function: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenat

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=79, Percent_Identity=51.8987341772152, Blast_Score=91, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12607; Mature: 12607

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
4.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINQVDFFKCLSDQTRLNILKLVLNKQNICVCELTEQLELSQPKISRHLALLRTHGVLLD
CCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCHHCCCCCHHHHHHHHHHHCCEEEE
ERKGQWVYYSLNPDLPVWALDILKVIENDESGTKVKQQDQSFITTTCCD
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MINQVDFFKCLSDQTRLNILKLVLNKQNICVCELTEQLELSQPKISRHLALLRTHGVLLD
CCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECCHHCCCCCHHHHHHHHHHHCCEEEE
ERKGQWVYYSLNPDLPVWALDILKVIENDESGTKVKQQDQSFITTTCCD
CCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2408017; 1838573; 8416957 [H]